Search Results - "Del ZOPPO, G. J."

The neurovascular unit in the setting of stroke by Del Zoppo, G. J.

“…del Zoppo GJ (University of Washington, Seattle, WA, USA). The neurovascular unit in the setting of stroke (Review). J Intern Med 2010; 267: 156–171. . …”
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Ischaemic damage of brain microvessels: inherent risks for thrombolytic treatment in stroke by DEL ZOPPO, GREGORY J, VON KUMMER, RÜDIGER, HAMANN, GERHARD F

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Inflammation and the neurovascular unit in the setting of focal cerebral ischemia by del Zoppo, G.J

“…Abstract Responses to focal cerebral ischemia by neurons and adjacent microvessels are rapid, simultaneous, and topographically related. Recent observations…”
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Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat) by Garcia, JH, Liu, KF, Yoshida, Y, Lian, J, Chen, S, del Zoppo, GJ

“…The results of several experimental studies of focal ischemia and anecdotal observations suggest that leukocytes may contribute to the injury initiated by an…”
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Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons by DEL ZOPPO, G. J, SCHMID-SCHÖNBEIN, G. W, MORI, E, COPELAND, B. R, CHENG-MING CHANG

“…Microvascular perfusion defects may accompany sustained occlusion and subsequent reperfusion of the middle cerebral artery; however, the nature of such…”
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Hemorrhagic transformation within 36 hours of a cerebral infarct : Relationships with early clinical deterioration and 3-month outcome in the European Cooperative Acute Stroke Study I (ECASS I) Cohort by FIORELLI, M, BASTIANELLO, S, VON KUMMER, R, DEL ZOPPO, G. J, LARRUE, V, LESAFFRE, E, RINGLEB, A. P, LORENZANO, S, MANELFE, C, BOZZAO, L

“…The clinical correlates of the varying degrees of early hemorrhagic transformation of a cerebral infarct are unclear. We investigated the cohort of a…”
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Matrix Metalloproteinases Increase Very Early During Experimental Focal Cerebral Ischemia by Heo, Ji Hoe, Lucero, Jacinta, Abumiya, Takeo, Koziol, James A., Copeland, Brian R., del Zoppo, Gregory J.

“…Microvascular integrity is lost during focal cerebral ischemia. The degradation of the basal lamina and extracellular matrix are, in part, responsible for the…”
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Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association by Goldstein, L B, Adams, R, Becker, K, Furberg, C D, Gorelick, P B, Hademenos, G, Hill, M, Howard, G, Howard, V J, Jacobs, B, Levine, S R, Mosca, L, Sacco, R L, Sherman, D G, Wolf, P A, del Zoppo, G J

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Primary prevention of ischemic stroke: A Statement for Healthcare Professionals from the Stroke Council of the American Heart Association by GOLDSTEIN, Larry B, ADAMS, Robert, LEVINE, Steven R, MOSCA, Lori, SACCO, Ralph L, SHERMAN, David G, WOLF, Philip A, DEL ZOPPO, Gregory J, BECKER, Kyra, FURBERG, Curt D, GORELICK, Philip B, HADEMENOS, George, HILL, Martha, HOWARD, George, HOWARD, Virginia J, JACOBS, Bradley

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Vascular matrix adhesion and the blood-brain barrier by Del Zoppo, G J, Milner, R, Mabuchi, T, Hung, S, Wang, X, Koziol, J A

“…The integrity of the cerebral microvasculature depends on the interaction between its component cells and the extracellular matrix, as well as reorganized…”
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Localization of tissue plasminogen activator in the endothelium of a limited number of vessels by Levin, EG, del Zoppo, GJ

“…The immunolocalization of tissue plasminogen activator (tPA) was assessed in vessels of various sizes from baboons. Femoral artery and vein, carotid artery,…”
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Advances in the Vascular Pathophysiology of Ischemic Stroke by del Zoppo, Gregory J, Hallenbeck, John M

“…The cerebral vascular supply is constructed to protect the cerebral hemispheres and brainstem from the consequences of blood flow cessation. Reversal of blood…”
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Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion by Hamann, G F, Okada, Y, del Zoppo, G J

“…Hemorrhagic transformation after cerebral ischemia is a well known clinical concern. The frequency of intact basal lamina (BL), identified by laminin antigen,…”
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Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody : A bedside-to-bench study by FURUYA, Kazuhide, TAKEDA, Hidetaka, DEL ZOPPO, Gregory J, HALLENBECK, John M, AZHAR, Salman, MCCARRON, Richard M, YONG CHEN, RUETZLER, Christl A, WOLCOTT, Karen M, DEGRABA, Thomas J, ROTHLEIN, Robert, HUGLI, Tony E

“…Enlimomab, a murine monoclonal anti-human intercellular adhesion molecule (ICAM)-1 antibody, had a negative outcome in a multicenter acute-stroke trial. We did…”
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Local intra-arterial fibrinolytic therapy in acute carotid territory stroke: a pilot study by DEL ZOPPO, G. J, FERBERT, A, OTIS, S, BRÜCKMANN, H, HACKE, W, ZYROFF, J, HARKER, L. A, ZEUMER, H

“…The possibility that intra-arterial local infusion of fibrinolytic agents may achieve recanalization of previously occluded carotid territory arteries in acute…”
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Thrombolysis for acute ischaemic stroke by Wardlaw, Joanna M, Murray, Veronica, Berge, Eivind, del Zoppo, Gregory J

“…Most strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain…”
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Models of Focal Cerebral Ischemia in the Nonhuman Primate by Fukuda, Shunichi, del Zoppo, Gregory J.

“…Ischemic stroke is a uniquely human disease syndrome. Models of focal cerebral ischemia developed in nonhuman primates provide clinically relevant platforms…”
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P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion by Okada, Y, Copeland, B R, Mori, E, Tung, M M, Thomas, W S, del Zoppo, G J

“…Polymorphonuclear leukocytes have been implicated in the development of the "no-reflow" phenomenon after focal cerebral ischemia and reperfusion. To further…”
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Focal cerebral ischemia and hemostasis: a PAI‐1 conundrum by DEL ZOPPO, G. J.

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Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons by MORI, E, DEL ZOPPO, G. J, CHAMBERS, J. D, COPELAND, B. R, ARFORS, K. E

“…While polymorphonuclear leukocytes may contribute to the "no-reflow" phenomenon after focal cardiac and skeletal muscle ischemia/reperfusion, their…”
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