Search Results - "Del Rosso, M."

Type II CRISPR/Cas9 approach in the oncological therapy by Biagioni, A, Chillà, A, Andreucci, E, Laurenzana, A, Margheri, F, Peppicelli, S, Del Rosso, M, Fibbi, G

“…CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a prokaryotic adaptable immune mechanism used by many bacteria and archaea to protect…”
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Endothelial Progenitor Cells in Sprouting Angiogenesis: Proteases Pave the Way by Laurenzana, A, Fibbi, G, Margheri, F, Biagioni, A, Luciani, C, Del Rosso, M, Chillà, A

“…Sprouting angiogenesis consists of the expansion and remodelling of existing vessels, where the vascular sprouts connect each other to form new vascular loops…”
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u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression by Ciavarella, S, Laurenzana, A, De Summa, S, Pilato, B, Chillà, A, Lacalamita, R, Minoia, C, Margheri, F, Iacobazzi, A, Rana, A, Merchionne, F, Fibbi, G, Del Rosso, M, Guarini, A, Tommasi, S, Serratì, S

“…Multiple Myeloma (MM) is a B-cell malignancy in which clonal plasma cells progressively expand within the bone marrow (BM) as effect of complex interactions…”
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Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases by MARGHERI, F, D'ALESSIO, S, RUCCI, N, BOLOGNA, M, TETI, A, MONIA, B, FIBBI, G, DEL ROSSO, M, SERRATI, S, PUCCI, M, ANNUNZIATO, F, COSMI, L, LIOTTA, F, ANGELI, R, ANGELUCCI, A, GRAVINA, G. L

“…An important factor implicated in tumor cell predisposition for invasion and metastasis is the malignancy-related upregulation of urokinase plasminogen…”
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Systemic sclerosis fibroblasts inhibit in vitro angiogenesis by MMP-12-dependent cleavage of the endothelial cell urokinase receptor by Serratì, S, Cinelli, M, Margheri, F, Guiducci, S, Del Rosso, A, Pucci, M, Fibbi, G, Bazzichi, L, Bombardieri, S, Matucci-Cerinic, M, Del Rosso, M

“…Failure of endothelial cells to develop new vessels in response to hypoxia is a distinctive feature of systemic sclerosis (SSc) in the avascular phase. We have…”
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Deflazacort modulates the fibrinolytic pattern and reduces uPA-dependent chemioinvasion and proliferation in rheumatoid arthritis synoviocytes by Del Rosso, A., Cinelli, M., Guiducci, S., Pignone, A., Fibbi, G., Margheri, F., Gabrielli, A., Giacomelli, R., Coppini, A., Del Rosso, M., Matucci Cerinic, M.

“…Objective. Extracellular fibrinolysis, controlled by the cell-associated fibrinolytic system (urokinase plasminogen activator, uPA; uPA receptor, uPAR;…”
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The β-Subunit of Cholera Toxin has a High Affinity for Ganglioside GM1 Embedded into Solid Supported Lipid Membranes with a Lipid Raft-Like Composition by Margheri, G., D’Agostino, R., Trigari, S., Sottini, S., Del Rosso, M.

“…In this communication, we report on the fabrication of GM1-rich solid-supported bilayer lipid membranes (ssBLM) made of sphingomyelin and cholesterol, the main…”
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Fabrication of GM3-Enriched Sphingomyelin/Cholesterol Solid-Supported Lipid Membranes on Au/SiO2 Plasmonic Substrates by Margheri, G., D’Agostino, R., Del Rosso, M., Trigari, S.

“…The fabrication of solid-supported artificial lipid bilayers enriched with biological agents is an important step for acquiring more insights into their…”
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Piascledine modulates the production of VEGF and TIMP-1 and reduces the invasiveness of rheumatoid arthritis synoviocytes by Cinelli, M., Guiducci, S., Del Rosso, A., Pignone, A., Del Rosso, M., Fibbi, G., Serratì, S., Gabrielli, A., Giacomelli, R., Piccardi, N., Matucci Cerinic, M.

“…Background: In rheumatoid arthritis (RA), hypertrophy of the synovial membrane generates a tumour-like pannus that invades the joint cavity and erodes…”
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TNF-alpha-converting enzyme cleaves the macrophage colony-stimulating factor receptor in macrophages undergoing activation by Rovida, E, Paccagnini, A, Del Rosso, M, Peschon, J, Dello Sbarba, P

“…We previously reported that macrophage activators such as LPS, IL-2, and IL-4 down-modulate the M-CSFR via a mechanism involving protein kinase C and…”
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Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression by Serratì, S, Margheri, F, Fibbi, G, Di Cara, G, Minafra, L, Pucci-Minafra, I, Liotta, F, Annunziato, F, Pucci, M, Del Rosso, M

“…Here we show the increase of invasion of three breast cancer cell lines (8701-BC, MDA-MB-231 and SKBR3) upon long-term co-incubation with culture medium of…”
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Multiple pathways of cell invasion are regulated by multiple families of serine proteases by Del Rosso, Mario, Fibbi, Gabriella, Pucci, Marco, D'Alessio, Silvia, Del Rosso, Angela, Magnelli, Lucia, Chiarugi, Vincenzo

“…The complex process of tumor invasion requires the coordinated expression and activity of cell-substratum adhesive interactions and of cell-associated protease…”
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Genetic diseases with impaired central respiratory control by Rosso Lourdes M. Del, Ferri Raffaele

“…Respiration is controlled by the complex orchestration of central nervous system centers, peripheral chemoreceptors and muscles of respiration and is shaped by…”
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The urokinase-type plasminogen activator system and inflammatory joint diseases by DEL ROSSO, M, FIBBI, G, CERINIC, M. M

“…Much evidence indicates that the urokinase plasminogen activator (u-PA), the urokinase receptor (u-PAR) and the serpin inhibitors are critical in cell invasion…”
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Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis by Guiducci, S, Del Rosso, A, Cinelli, M, Perfetto, F, Livi, R, Rossi, A, Gabrielli, A, Giacomelli, R, Iori, N, Fibbi, G, Del Rosso, M, Cerinic, M Matucci

“…Extracellular fibrinolysis, controlled by the membrane-bound fibrinolytic system, is involved in cartilage damage and rheumatoid arthritis (RA) synovitis…”
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In vitro anti-proliferative and anti-invasive role of amino-terminal fragment of urokinase-type plasminogen activator on 8701-BC breast cancer cells by LUPARELLO, C, DEL ROSSO, M

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In Vitro anti-proliferative and anti-invasive role of aminoterminal fragment of urokinase-type plasminogen activator on 8701-BC breast cancer cells by Luparello, C., Del Rosso, M.

“…8701-BC cells, derived from a primary carcinoma of the breast, constitutively express mRNA for urokinase-type plasminogen activator (uPA). In this paper, we…”
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Transforming Growth Factor Beta-1 Stimulates Invasivity of Hepatic Stellate Cells by Engagement of the Cell-associated Fibrinolytic System by Fibbi, Gabriella, Pucci, Marco, D'alessio, Silvia, Grappone, Cecilia, Pellegrini, Giulia, Salzano, Renata, Casini, Alessandro, Milani, Stefano, Rosso, Mario Del

“…The activation of hepatic stellate cells (HSC) during liver fibrogenesis has been shown to be mediated by paracrine and autocrine loops involving transforming…”
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Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells by Fibbi, G, Ziche, M, Morbidelli, L, Magnelli, L, Del Rosso, M

“…On the basis of 125I-labeled plasminogen activator binding analysis we have found that bovine adrenal capillary endothelial cells have specific receptors for…”
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Antisense oligonucleotides against the urokinase receptor: a therapeutic strategy for the control of cell invasion in rheumatoid arthritis and cancer by Del Rosso, M, Fibbi, G, Pucci, M, Cerinic, M M

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