Search Results - "Del Rosso, James Q."

The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management by Del Rosso, James Q, Kircik, Leon

“…Sebum physiology and its contributions to acne vulgaris (AV) pathophysiology have been long debated. Within the pilosebaceous unit, androgens drive sebocyte…”
Get full text

The cutaneous effects of androgens and androgen-mediated sebum production and their pathophysiologic and therapeutic importance in acne vulgaris by Del Rosso, James Q, Kircik, Leon

“…The recognition of an association between the development of acne vulgaris (AV) and pubertal hormonal changes during adolescence dates back almost 100 years…”
Get full text

Management of facial erythema of rosacea: What is the role of topical α- adrenergic receptor agonist therapy? by Del Rosso, James Q., DO, FAOCD

“…Several more recent advances have led to a better understanding of the pathophysiologic mechanisms involved in rosacea and therapeutic modalities used for…”
Get full text

Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel by Coda, Alvin B., MD, Hata, Tissa, MD, Miller, Jeremiah, MD, Audish, David, BS, Kotol, Paul, BS, Two, Aimee, MD, Shafiq, Faiza, MBBS, Yamasaki, Kenshi, MD, PhD, Harper, Julie C., MD, Del Rosso, James Q., DO, Gallo, Richard L., MD, PhD

“…Background Excess cathelicidin and kallikrein 5 (KLK5) have been hypothesized to play a role in the pathophysiology of rosacea. Objective We sought to evaluate…”
Get full text

Topical clindamycin for acne vulgaris: analysis of gastrointestinal events by Pelet Del Toro, Natalia M, Strunk, Andrew, Wu, Jashin J, Stein Gold, Linda, Del Rosso, James Q, Brodell, Robert T, Han, George

“…Topical clindamycin, a lincosamide antibiotic, is commonly combined with benzoyl peroxide or a retinoid for acne vulgaris (AV) treatment. While oral and…”
Get full text

Evidence-based recommendations for the management of acne fulminans and its variants by Greywal, Tanya, MD, Zaenglein, Andrea L., MD (co-chair), Baldwin, Hilary E., MD, Bhatia, Neal, MD, Chernoff, Karen A., MD, Del Rosso, James Q., DO, Eichenfield, Lawrence F., MD, Levin, Marc H., MD, PhD, Leyden, James J., MD, Thiboutot, Diane M., MD, Webster, Guy F., MD, PhD, Friedlander, Sheila Fallon, MD (co-chair)

“…Background Acne fulminans (AF) is a severe variant of inflammatory acne. It typically manifests as an explosive worsening and ulceration of skin lesions, and…”
Get full text

Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin by Tanghetti, Emil A., Zeichner, Joshua A., Gold, Michael, Sadick, Neil, Cook-Bolden, Fran E., Kircik, Leon H., Stein Gold, Linda, Weiss, Jonathan, Tyring, Stephen K., Del Rosso, James Q., Guenin, Eric

“…Excessive sebum production is a factor in acne development. Tazarotene 0.045% lotion has demonstrated reductions in acne lesions and acne-induced sequelae…”
Get full text

Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for treatment of rosacea by Del Rosso, James Q., DO, Webster, Guy F., MD, PhD, Jackson, Mark, MD, Rendon, Marta, MD, Rich, Phoebe, MD, Torok, Helen, MD, Bradshaw, Mark, PhD

“…Background Doxycycline monotherapy at antimicrobial doses has been shown to be effective for the treatment of rosacea. Objective To evaluate the efficacy and…”
Get full text

Wound care in the dermatology office: Where are we in 2011? by Del Rosso, James Q., DO

“…Dermatologists perform several minor surgical procedures in their offices on a daily basis that result in superficial cutaneous wounds. Conventionally, the…”
Get full text

Reply to “Allergic contact dermatitis to topical brimonidine tartrate gel 0.33% for treatment of rosacea” by Del Rosso, James Q., DO

Get full text

What Is PFE? It May Just Be Time You Found Out by Del Rosso, James Q.

“…With all the literature and research we have on acne and rosacea, there are still many unanswered questions. Over time, as we uncover more information on both…”
Get more information

Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease by Armillei, Maria K, Lomakin, Ivan B, Del Rosso, James Q, Grada, Ayman, Bunick, Christopher G

“…Clindamycin is a highly effective antibiotic of the lincosamide class. It has been widely used for decades to treat a range of skin and soft tissue infections…”
Get full text

Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 Analysis by Kircik, Leon H., Stein Gold, Linda, Gold, Michael, Weiss, Jonathan S., Harper, Julie C., Del Rosso, James Q., Bunick, Christopher G., Bhatia, Neal, Tanghetti, Emil A., Eichenfield, Lawrence F., Baldwin, Hilary, Draelos, Zoe D., Callender, Valerie D., Han, George, Gooderham, Melinda J., Sadick, Neil, Lupo, Mary P., Lain, Edward (Ted), Werschler, William Philip

“…Introduction A three-pronged approach to acne treatment combining an antibiotic, antimicrobial, and retinoid may be more efficacious than single/double…”
Get full text

Sarecycline Demonstrated Reduced Activity Compared to Minocycline against Microbial Species Representing Human Gastrointestinal Microbiota by Ghannoum, Mahmoud A, Long, Lisa, Bunick, Christopher G, Del Rosso, James Q, Gamal, Ahmed, Tyring, Stephen K, McCormick, Thomas S, Grada, Ayman

“…Prolonged use of broad-spectrum tetracycline antibiotics such as minocycline and doxycycline may significantly alter the gut and skin microbiome leading to…”
Get full text

Reduced blood-brain barrier penetration of acne vulgaris antibiotic sarecycline compared to minocycline corresponds with lower lipophilicity by Grada, Ayman, Del Rosso, James Q, Moore, Angela Y, Stein Gold, Linda, Harper, Julie, Damiani, Giovanni, Shaw, Katharina, Obagi, Sabine, Salem, Raidah J, Tanaka, S Ken, Bunick, Christopher G

“…Vestibular side effects such as dizziness and vertigo can be a limitation for some antibiotics commonly used to treat acne, rosacea, and other dermatology…”
Get full text

Acne and the Internet by Zeichner, Joshua A., MD, Del Rosso, James Q., DO

“…The Internet provides both education and miseducation for acne patients. Although some sites provide disease background information and objective treatment…”
Get full text

Anti-Inflammatory Activity of Tetracyclines by Webster, Guy, MD, PhD, Del Rosso, James Q., DO, FAOCD

“…Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity,…”
Get full text

When Acne is Not Acne by Del Rosso, James Q., DO, Silverberg, Nanette, MD, Zeichner, Joshua A., MD

“…Acne vulgaris (AV) is considered a straightforward diagnosis made clinically without specific diagnostic testing. However, certain disorders may simulate AV,…”
Get full text

Psychosocial judgements and perceptions of adolescents with acne vulgaris: A blinded, controlled comparison of adult and peer evaluations by Ritvo, Eva, Del Rosso, James Q, Stillman, Mark A, La Riche, Christopher

“…The purpose of the current survey was to evaluate how teenagers and adults view teens with acne as compared to those with smooth, clear skin. We also surveyed…”
Get full text

Optimizing Use of Oral Antibiotics in Acne Vulgaris by Del Rosso, James Q., DO, FAOCD, Kim, Grace, DO

“…Oral antibiotics are commonly used to treat acne vulgaris, primarily in patients presenting with moderate to severe facial or truncal disease severity. These…”
Get full text