Search Results - "Del Re, Marzia"

Updates on liquid biopsy: current trends and future perspectives for clinical application in solid tumors by Pinzani, Pamela, D'Argenio, Valeria, Del Re, Marzia, Pellegrini, Cristina, Cucchiara, Federico, Salvianti, Francesca, Galbiati, Silvia

“…Despite advances in screening and therapeutics cancer continues to be one of the major causes of morbidity and mortality worldwide. The molecular profile of…”
Get more information

EGFR-TKIs in non-small-cell lung cancer: focus on clinical pharmacology and mechanisms of resistance by Fogli, Stefano, Polini, Beatrice, Re, Marzia Del, Petrini, Iacopo, Passaro, Antonio, Crucitta, Stefania, Rofi, Eleonora, Danesi, Romano

“…The clinical introduction of EGFR-TKIs within the oncologic armamentarium has changed the therapeutic landscape of non-small-cell lung cancer (NSCLC) creating…”
Get full text

Are anti-PD1 and anti-PD-L1 alike? The non-small-cell lung cancer paradigm by Banna, Giuseppe Luigi, Cantale, Ornella, Bersanelli, Melissa, Del Re, Marzia, Friedlaender, Alex, Cortellini, Alessio, Addeo, Alfredo

“…Anti-PD1 and anti-PD-L1 agents may have intrinsic and clinically relevant differences in the treatment of non-small cell lung cancer (NSCLC) patients. By…”
Get full text

Comprehensive pharmacogenetic analysis of DPYD, UGT, CDA, and ABCB1 polymorphisms in pancreatic cancer patients receiving mFOLFIRINOX or gemcitabine plus nab-paclitaxel by Vivaldi, Caterina, Crucitta, Stefania, Catanese, Silvia, Cucchiara, Federico, Arrigoni, Elena, Pecora, Irene, Rofi, Eleonora, Fornaro, Lorenzo, Salani, Francesca, Massa, Valentina, Vasile, Enrico, Morganti, Riccardo, Danesi, Romano, Del Re, Marzia

“…Modified FOLFIRINOX (mFOLFIRINOX) and gemcitabine + nab-paclitaxel (GemNab) regimens represent a standard treatment in advanced pancreatic cancer (aPC). DPYD…”
Get full text

Pharmacological Basis of Breast Cancer Resistance to Therapies - An Overview by Crucitta, Stefania, Cucchiara, Federico, Sciandra, Francesca, Cerbioni, Annalisa, Diodati, Lucrezia, Rafaniello, Concetta, Capuano, Annalisa, Fontana, Andrea, Fogli, Stefano, Danesi, Romano, Re, Marzia Del

“…Breast Cancer (BC) is a molecular heterogeneous disease and patients with similar clinico-pathological characteristics often display different response to…”
Get more information

Circulating biomarkers of response to immunotherapy in cancer treatment by Del Re, Marzia, Gianfilippo, Giulia, Crucitta, Stefania, Addeo, Alfredo, van Schaik, Ron Hn, Danesi, Romano

“…Recently, it has been demonstrated that high TMB correlates with high response rates to checkpoint inhibitors, probably due to the immunogenic neoantigens…”
Get full text

Clinical pharmacology of intravitreal anti-VEGF drugs by Fogli, Stefano, Del Re, Marzia, Rofi, Eleonora, Posarelli, Chiara, Figus, Michele, Danesi, Romano

“…Clinical efficacy of intravitreal anti-VEGF drugs has been widely demonstrated in several angiogenesis-driven eye diseases including diabetic macular edema and…”
Get full text

Exploring the epigenetic susceptibility mechanisms of lung cancer through DNA methylation markers by Rolfo, Christian, Del Re, Marzia, Russo, Alessandro

“…During lung carcinogenesis, different epigenetic changes occur and, among these, DNA methylation aberrations play a critical role, representing an appealing…”
Get full text

EGFR signaling pathway as therapeutic target in human cancers by Levantini, Elena, Maroni, Giorgia, Del Re, Marzia, Tenen, Daniel G.

“…Epidermal Growth Factor Receptor (EGFR) enacts major roles in the maintenance of epithelial tissues. However, when EGFR signaling is altered, it becomes the…”
Get full text

4th ESPT Conference: pharmacogenomics and personalized medicine – research progress and clinical implementation by Sipeky, Csilla, Llerena, Adrián, Manolopoulos, Vangelis G, Pearson, Ewan, Mlakar, Vid, Gozzo, Lucia, Simmaco, Maurizio, Marchetti, Paolo, Re, Marzia Del, Stankovic, Sanja, Meyer, Urs, Cascorbi, Ingolf, Ingelman-Sundberg, Magnus, Suarez-Kurtz, Guilherme, Marc, Janja, Katsila, Theodora, Paulmichl, Markus, Nofziger, Charity, Ansari, Marc, Drago, Filippo, van Schaik, Ron Hn

“…The Fourth European Society of Pharmacogenomics and Personalized Therapy biennial conference was organized in collaboration with the Italian Society of…”
Get full text

ANKRD44 Gene Silencing: A Putative Role in Trastuzumab Resistance in Her2-Like Breast Cancer by La Ferla, Marco, Lessi, Francesca, Aretini, Paolo, Pellegrini, Davide, Franceschi, Sara, Tantillo, Elena, Menicagli, Michele, Marchetti, Ivo, Scopelliti, Claudia, Civita, Prospero, De Angelis, Claudia, Diodati, Lucrezia, Bertolini, Ilaria, Roncella, Manuela, McDonnell, Liam A, Hochman, Jacob, Del Re, Marzia, Scatena, Cristian, Naccarato, Antonio G, Fontana, Andrea, Mazzanti, Chiara M

“…Trastuzumab is an effective therapeutic treatment for Her2-like breast cancer; despite this most of these tumors develop resistance to therapy due to specific…”
Get full text

The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients by Del Re, Marzia, Biasco, Elisa, Crucitta, Stefania, Derosa, Lisa, Rofi, Eleonora, Orlandini, Cinzia, Miccoli, Mario, Galli, Luca, Falcone, Alfredo, Jenster, Guido W, van Schaik, Ron H, Danesi, Romano

“…Abstract Background The androgen receptor splice variant 7 (AR-V7) is associated with resistance to hormonal therapy in castration-resistant prostate cancer…”
Get full text

Recurrent USP6 rearrangement in a subset of atypical myofibroblastic tumours of the soft tissues: low‐grade myofibroblastic sarcoma or atypical/malignant nodular fasciitis? by Arcovito, Giorgia, Crucitta, Stefania, Del Re, Marzia, Caporalini, Chiara, Palomba, Annarita, Nozzoli, Filippo, Franchi, Alessandro

“…Aims Low‐grade myofibroblastic sarcoma (LGMS) is a rarely metastasizing myofibroblastic tumour mostly affecting extremities and the head and neck of adults…”
Get full text

Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients by Del Re, Marzia, Bertolini, Ilaria, Crucitta, Stefania, Fontanelli, Lorenzo, Rofi, Eleonora, De Angelis, Claudia, Diodati, Lucrezia, Cavallero, Diletta, Gianfilippo, Giulia, Salvadori, Barbara, Fogli, Stefano, Falcone, Alfredo, Scatena, Cristian, Naccarato, Antonio Giuseppe, Roncella, Manuela, Ghilli, Matteo, Morganti, Riccardo, Fontana, Andrea, Danesi, Romano

“…Purpose Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) improve progression-free survival (PFS) in patients with hormone receptor-positive (HR+) advanced…”
Get full text

Clinical pharmacology and drug-drug interactions of lenvatinib in thyroid cancer by Fogli, Stefano, Gianfilippo, Giulia, Cucchiara, Federico, Del Re, Marzia, Valerio, Laura, Elisei, Rossella, Danesi, Romano

“…[Display omitted] •Lenvatinib is the first therapeutic option in patients with radioiodine-refractory differentiated thyroid cancer.•Common adverse drug…”
Get full text

Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer by Casanova-Salas, Irene, Athie, Alejandro, Boutros, Paul C., Del Re, Marzia, Miyamoto, David T., Pienta, Kenneth J., Posadas, Edwin M., Sowalsky, Adam G., Stenzl, Arnulf, Wyatt, Alexander W., Mateo, Joaquin

“…Genomic stratification can impact prostate cancer (PC) care through diagnostic, prognostic, and predictive biomarkers that aid in clinical decision-making. The…”
Get full text

Comparative evaluation of molecular methods for the quantitative measure of torquetenovirus viremia, the new surrogate marker of immune competence by Macera, Lisa, Spezia, Pietro Giorgio, Medici, Chiara, Rofi, Eleonora, Del Re, Marzia, Focosi, Daniele, Mazzetti, Paola, Navarro, David, Antonelli, Guido, Danesi, Romano, Pistello, Mauro, Maggi, Fabrizio

“…Background Torquetenovirus (TTV) viremia is emerging as a promising tool to assess functional immune competence, to predict posttransplant immune‐related…”
Get full text

Understanding the Mechanisms of Resistance in EGFR -Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy by Del Re, Marzia, Crucitta, Stefania, Gianfilippo, Giulia, Passaro, Antonio, Petrini, Iacopo, Restante, Giuliana, Michelucci, Angela, Fogli, Stefano, de Marinis, Filippo, Porta, Camillo, Chella, Antonio, Danesi, Romano

“…Liquid biopsy has emerged as an alternative source of nucleic acids for the management of Epidermal Growth Factor Receptor ( )-mutant non-Small Cell Lung…”
Get full text

Androgen receptor (AR) splice variant 7 and full‐length AR expression is associated with clinical outcome: a translational study in patients with castrate‐resistant prostate cancer by Del Re, Marzia, Crucitta, Stefania, Sbrana, Andrea, Rofi, Eleonora, Paolieri, Federico, Gianfilippo, Giulia, Galli, Luca, Falcone, Alfredo, Morganti, Riccardo, Porta, Camillo, Efstathiou, Eleni, Schaik, Ron, Jenster, Guido, Danesi, Romano

“…Objectives To investigate if full‐length androgen receptor (AR‐FL) is associated with resistance to androgen receptor (AR)‐directed therapy independently…”
Get full text

The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide by Del Re, Marzia, Fogli, Stefano, Derosa, Lisa, Massari, Francesco, De Souza, Paul, Crucitta, Stefania, Bracarda, Sergio, Santini, Daniele, Danesi, Romano

“…Graphical abstract…”
Get full text