Search Results - "Del Giudice, Simona"
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Changes in gene expression in human skeletal stem cells transduced with constitutively active Gsα correlates with hallmark histopathological changes seen in fibrous dysplastic bone
Published in PloS one (01-01-2020)“…Fibrous dysplasia (FD) of bone is a complex disease of the skeleton caused by dominant activating mutations of the GNAS locus encoding for the α subunit of the…”
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Journal Article -
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AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody
Published in PLoS genetics (27-08-2021)“…To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for…”
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Mice with reduced expression of the telomere‐associated protein Ft1 develop p53‐sensitive progeroid traits
Published in Aging cell (01-08-2018)“…Summary Human AKTIP and mouse Ft1 are orthologous ubiquitin E2 variant proteins involved in telomere maintenance and DNA replication. AKTIP also interacts with…”
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Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer
Published in Frontiers in cell and developmental biology (23-03-2022)“…The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of…”
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p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice
Published in Frontiers in genetics (27-11-2018)“…Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. Seizures have been linked to multiple drivers including DNA damage…”
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Changes in gene expression in human skeletal stem cells transduced with constitutively active Gs[alpha] correlates with hallmark histopathological changes seen in fibrous dysplastic bone
Published in PloS one (30-01-2020)“…Fibrous dysplasia (FD) of bone is a complex disease of the skeleton caused by dominant activating mutations of the GNAS locus encoding for the [alpha] subunit…”
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Journal Article