Search Results - "Del Batlle, A M"

ALA and ALA hexyl ester in free and liposomal formulations for the photosensitisation of tumour organ cultures by CASAS, A, PEROTTI, C, SACCOLITI, M, SACCA, P, FUKUDA, H, DEL C BATTLE, A. M

“…In spite of the wide range of tumours successfully treated with 5-aminolevulinic acid mediated photodynamic therapy, the fact that 5-aminolevulinic acid has…”
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Functional associations of genetic variants involved in the clinical manifestation of erythropoietic protoporphyria in the Argentinean population by Colombo, F.P., Rossetti, M.V., Méndez, M., Martínez, J.E., Enríquez de Salamanca, R., del C. Batlle, A.M., Parera, V.E.

“…Background  Combined inheritance of genetic variants in ferrochelatase gene (FECH) are implicated in clinical manifestation of Erythropoietic Protoporphyria…”
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Comparative effect of ALA derivatives on protoporphyrin IX production in human and rat skin organ cultures by CASAS, A, DEL C. BATLLE, A. M, BUTLER, A. R, ROBERTSON, D, BROWN, E. H, MACROBERT, A, RILEY, P. A

“…Samples of human and rat skin in short-term organ culture exposed to ALA or a range of hydrophobic derivatives were examined for their effect on the…”
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Tissue distribution and kinetics of endogenous porphyrins synthesized after topical application of ALA in different vehicles by CASAS, A, FUKUDA, H, BATLLE, A. M. Del C

“…The use of 5-aminolaevulinic acid (ALA) is gaining increasing attention for photosensitization in photodynamic therapy of superficially localized tumours. The…”
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The very first description of a patient with hepatoerythropoietic porphyria in Argentina. Biochemical and molecular studies by Granata, B X, Parera, V E, Melito, V A, Teijo, M J, Batlle, A M del C, Rossetti, M V

“…Hepatoerythropoietic Porphyria (HEP) is the rare homozygous form of Porphyria Cutanea Tarda (PCT). It is characterized clinically by the early onset of severe…”
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Induction of hepatic aminolevulinate acid synthetase activity by isoflurane in a genetic model for erythropoietic protoporphyria by Buzaleh, A M, Morán-Jiménez, M J, Garcia-Bravo, M, Sampedro, A, Batlle, A M Del C, Enriquez de Salamanca, R, Fontanellas, A

“…Erythropoietic Protoporphyria (EPP) is an inherited deficiency of ferrochelatase, the last enzyme of the heme pathway. Under general anaesthesia, some patients…”
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Purification and properties of coproporphyrinogenase by del Batlle, A M, Benson, A, Rimington, C

“…1. Coproporphyrinogenase has been prepared from rat-liver mitochondria and its properties have been studied. The isoelectric point was found to be around pH5.0…”
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beta-Carotene partially prevents the damage induced by 1,4-dimethylaminoazobenzene in mice by Gerez, E, Vazquez, E, Caballero, F, Batlle, A M

“…Hepatocarcinogenesis (HC) induced by various carcinogens such as 1,4-dimethylaminoazobenzene (DAB) is a multistep and complex process. The anticancer efficacy…”
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Regulatory role of ALA-S and ALA-D in a haem-deficient mutant of Saccharomyces cerevisiae by Araujo, L S, Lombardo, M E, Del C Batlle, A M

“…The biochemical characteristics of a haem-deficient mutant strain B231 of Saccharomyces cerevisiae isolated from D273-10B strain are described. B231 strain…”
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Porphyrins, porphyrias, cancer and photodynamic therapy--a model for carcinogenesis by Batlle, A M

“…Porphyrins are the only and most powerful photosensitizers synthesized internally. To understand better the involvement of porphyrins in photosensitization…”
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Familial Porphyria Cutanea Tarda: Characterization of Seven Novel Uroporphyrinogen Decarboxylase Mutations and Frequency of Common Hemochromatosis Alleles by Mendez, Manuel, Sorkin, Lonnie, Rossetti, Maria Victoria, Astrin, Kenneth H., Batlle, Alcira M. del C., Parera, Victoria E., Aizencang, Gerardo, Desnick, Robert J.

“…Familial porphyria cutanea tarda (f-PCT) results from the half-normal activity of uroporphyrinogen decarboxylase (URO-D). Heterozygotes for this autosomal…”
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Acute intermittent porphyria: Biochemical and clinical analysis in the Argentinean population by De Siervi, Adriana, Rossetti, Marı́a V, Parera, Victoria E, Mendez, Manuel, Varela, Laura S, del C. Batlle, Alcira M

“…Acute intermittent porphyria (AIP) is the most common type of hepatic acute porphyria. In this work, we have analyzed the biochemical data of all Argentinean…”
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Enhancement of aminolevulinic acid based photodynamic therapy by adriamycin by Casas, Adriana, Fukuda, Haydee, Riley, Patrick, del C. Batlle, Alcira M

“…This paper reports on studies that evaluate the interaction between δ-aminolevulinic acid (ALA)-based photodynamic therapy (PDT) and adriamycin (ADM) in an…”
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Identification and characterization of two novel mutations that produce acute intermittent porphyria: A 3-base deletion (841-843delGGA) and a missense mutation (T35M) by Siervi, Adriana De, Cádiz, Débora E. Weiss, Parera, Victoria E., del C. Batlle, Alcira M., Rossetti, Maria Victoria

“…A partial deficiency of Porphobilinogen deaminase (PBGD) is responsible for acute intermittent porphyria (AIP). AIP is inherited in an autosomal dominant…”
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Two new mutations (H106P and L178V) in the protoporphyrinogen oxidase gene in Argentinean patients with variegate porphyria by De Siervi, Adriana, Parera, Victoria E., del C. Batlle, Alcira M., Rossetti, María V.

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Hepatic enzymatic metabolism alterations and oxidative stress during the onset of carcinogenesis: protective role of alpha-tocopherol by Gerez, E, Caballero, F, Vazquez, E, Polo, C, Batlle, A M

“…Oxidants play a role in several stages of carcinogenesis. A high antioxidant capacity is expected to protect 'initiated' cells from excessive oxidant toxicity…”
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Metabolic changes in the heme pathway driven by cyclophosphamide treatment in mice by Casas, A, Fukuda, H, Del C Batlle, A M

“…In previous work we found a 30% increase in the effectiveness of the photodynamic treatment of cancer when combined with the administration of cyclophosphamide…”
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The role of ALA-S and ALA-D in regulating porphyrin biosynthesis in a normal and a HEM R+ mutant strain of Saccharomyces cerevisiae by Correa García, S, Bermúdez Moretti, M, Cardalda, C, Rossetti, M V, Batlle, A M

“…Catabolite repression and derepression on delta-aminolevulinate synthase (ALA-S) and delta-aminolevulinate dehydratase (ALA-D) in a normal yeast strain, D27,…”
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STZ-induced diabetes in mice and heme pathway enzymes. Effect of allylisopropylacetamide and α-tocopherol by Polo, César F., Vázquez, Elba S., Gerez, Esther N., Caballero, Fabiana A., del C. Batlle, Alcira M.

“…A frequent coexistence of diabetes and porphyria disease has been reported. Under normal conditions, porphyrin biosynthesis is well regulated to only form the…”
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Identification and characterization of hydroxymethylbilane synthase mutations causing acute intermittent porphyria: Evidence for an ancestral founder of the common G111R mutation by De Siervi, A., Rossetti, M. V., Parera, V. E., Astrin, K. H., Aizencang, G. I., Glass, I. A., del C. Batlle, A. M., Desnick, R. J.

“…Acute intermittent porphyria (AIP), the most common hepatic porphyria, results from the half‐normal activity of hydroxymethylbilane synthase (HMB‐synthase; EC…”
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