Search Results - "Dekkers, P P"
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Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2012)“…The functional relevance of brain-derived neurotrophic factor (BDNF) is beginning to be well appreciated not only in mice, but also in humans. Because reduced…”
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What Do They Know? Investigating Students' Ability to Analyse Experimental Data in Secondary Physics Education
Published in International journal of science education (22-01-2021)“…This paper explores students' ability to analyse and interpret empirical data as inadequate data analysis skills and understandings may contribute to the…”
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Incidence and causes of colonoscopic perforations: a single-center case series
Published in Endoscopy (01-03-2011)“…Perforations are known to occur after colonoscopy. In a consecutive study the localization of the perforation was determined, and the etiology of the…”
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Redesigning a first year physics lab course on the basis of the procedural and conceptual knowledge in science model
Published in Physical review. Physics education research (22-03-2024)“…[This paper is part of the Focused Collection on Instructional labs: Improving traditions and new directions.] Acknowledgement of the limited learning outcomes…”
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The yield of colonoscopy in relation to the applicant
Published in International journal of colorectal disease (06-03-2019)Get full text
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Integrating argumentation in physics inquiry: A design and evaluation study
Published in Physical review. Physics education research (01-12-2023)“…This small-scale, qualitative study uses educational design research to explore how focusing on argumentation may contribute to students’ learning to engage in…”
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The first results of the “bevolkingsonderzoek” in the Zaanstreek region in The Netherlands
Published in International journal of colorectal disease (01-10-2018)“…This short communication describes the results with respect to stage of colorectal cancer in people detected via screening and patients with clinical…”
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Factors associated with long-term sick leave in sick-listed employees: a systematic review
Published in Occupational and environmental medicine (London, England) (01-03-2008)“…Objective: The objective of this systematic review was to investigate which factors are associated with continued sick leave among workers on sick leave for at…”
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Defining and Assessing Understandings of Evidence with the Assessment Rubric for Physics Inquiry: Towards Integration of Argumentation and Inquiry
Published in Physical review. Physics education research (01-02-2022)“…Physics inquiry can be interpreted as the construction of a cogent argument in which students apply inquiry knowledge and knowledge of physics to the…”
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Programmed Cell Death in Neuronal Development
Published in Science (American Association for the Advancement of Science) (05-04-2013)“…Life or death decisions in cortical interneurons during development are made independently of external cues, challenging current theory. Programmed cell death,…”
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'Would You Dare to Jump?' Fostering a Scientific Approach to Secondary Physics Inquiry
Published in International journal of science education (13-06-2022)“…Secondary school students often only use the rules for doing scientific inquiry when prompted, as if they fail to see the point of doing so. This qualitative…”
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Individual polyp detection rate in routine daily endoscopy practice depends on case-mix
Published in International journal of colorectal disease (01-07-2015)“…Introduction The adenoma detection rate (ADR), a marker of endoscopic quality, is confounded by selection bias. It is not known what the ADR is in normal daily…”
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Results of the 'bevolkingsonderzoek' in the Zaanstreek region in the Netherlands. Part 2
Published in Scandinavian journal of gastroenterology (03-06-2019)Get full text
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Plasticity in gustatory and nociceptive neurons controls decision making in C. elegans salt navigation
Published in Communications biology (09-09-2021)“…A conventional understanding of perception assigns sensory organs the role of capturing the environment. Better sensors result in more accurate encoding of…”
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Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (24-04-2007)“…In the cilia of the nematode Caenorhabditis elegans, anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3…”
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PACRG, a protein linked to ciliary motility, mediates cellular signaling
Published in Molecular biology of the cell (01-07-2016)“…Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia…”
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The changing prevalence of upper gastrointestinal endoscopic diagnoses: a single-centre study
Published in Netherlands journal of medicine (01-06-2012)“…Upper gastrointestinal (GI) endoscopy is increasingly applied in daily practice. Not many data are available on yearly changes in diagnostic yield, nor on…”
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Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia
Published in Blood (15-02-2000)“…Inhibition of the tissue factor pathway has been shown to attenuate the activation of coagulation and to prevent death in a gram-negative bacteremia primate…”
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Blood pressure variability, nocturnal heart rate variability and endothelial function predict recurrent cerebro-cardiovascular events following ischemic stroke
Published in Frontiers in cardiovascular medicine (16-11-2023)“…IntroductionCardiovascular parameters characterizing blood pressure (BP), heart rate (HR), endothelial function and arterial stiffness predict…”
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