Search Results - "Dekkers, Martijn P.J"

Death of developing neurons: New insights and implications for connectivity by Dekkers, Martijn PJ, Nikoletopoulou, Vassiliki, Barde, Yves-Alain

“…The concept that target tissues determine the survival of neurons has inspired much of the thinking on neuronal development in vertebrates, not least because…”
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Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans by Burghoorn, Jan, Dekkers, Martijn P.J, Rademakers, Suzanne, de Jong, Ton, Willemsen, Rob, Jansen, Gert

“…In the cilia of the nematode Caenorhabditis elegans, anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3…”
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Dauer pheromone and G-protein signaling modulate the coordination of intraflagellar transport kinesin motor proteins in C. elegans by Burghoorn, Jan, Dekkers, Martijn P.J, Rademakers, Suzanne, de Jong, Ton, Willemsen, Rob, Swoboda, Peter, Jansen, Gert

“…Cilia length and function are dynamically regulated by modulation of intraflagellar transport (IFT). The cilia of C. elegans amphid channel neurons provide an…”
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Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome by Deogracias, Rubén, Yazdani, Morteza, Dekkers, Martijn P. J, Guy, Jacky, Ionescu, Mihai Constantin S, Vogt, Kaspar E, Barde, Yves-Alain

“…The functional relevance of brain-derived neurotrophic factor (BDNF) is beginning to be well appreciated not only in mice, but also in humans. Because reduced…”
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Frequency and evolution of sleep-wake disturbances after ischemic stroke: A 2-year prospective study of 437 patients by Duss, Simone B., Bauer-Gambelli, Stefan A., Bernasconi, Corrado, Dekkers, Martijn P.J., Gorban-Peric, Corina, Kuen, Doris, Seiler, Andrea, Oberholzer, Michael, Alexiev, Filip, Lippert, Julian, Brill, Anne-Kathrin, Ott, Sebastian R., Zubler, Frédéric, Horvath, Thomas, Schmidt, Markus H., Manconi, Mauro, Bassetti, Claudio L.A.

“…In the absence of systematic and longitudinal data, this study prospectively assessed both frequency and evolution of sleep-wake disturbances (SWD) after…”
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Programmed Cell Death in Neuronal Development by Dekkers, Martijn P. J., Barde, Yves-Alain

“…Life or death decisions in cortical interneurons during development are made independently of external cues, challenging current theory. Programmed cell death,…”
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Measuring Sleep, Wakefulness, and Circadian Functions in Neurologic Disorders by Schmidt, Markus H., Dekkers, Martijn P.J., Baillieul, Sébastien, Jendoubi, Jasmine, Wulf, Marie-Angela, Wenz, Elena, Fregolente, Livia, Vorster, Albrecht, Gnarra, Oriella, Bassetti, Claudio L.A.

“…Neurologic disorders impact the ability of the brain to regulate sleep, wake, and circadian functions, including state generation, components of state (such as…”
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PACRG, a protein linked to ciliary motility, mediates cellular signaling by Loucks, Catrina M, Bialas, Nathan J, Dekkers, Martijn P J, Walker, Denise S, Grundy, Laura J, Li, Chunmei, Inglis, P Nick, Kida, Katarzyna, Schafer, William R, Blacque, Oliver E, Jansen, Gert, Leroux, Michel R

“…Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia…”
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Plasticity in gustatory and nociceptive neurons controls decision making in C. elegans salt navigation by Dekkers, Martijn P. J., Salfelder, Felix, Sanders, Tom, Umuerri, Oluwatoroti, Cohen, Netta, Jansen, Gert

“…A conventional understanding of perception assigns sensory organs the role of capturing the environment. Better sensors result in more accurate encoding of…”
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Blood pressure variability, nocturnal heart rate variability and endothelial function predict recurrent cerebro-cardiovascular events following ischemic stroke by Filchenko, Irina, Mürner, Nicolas, Dekkers, Martijn P. J., Baillieul, Sebastien, Duss, Simone B., Brill, Anne-Kathrin, Horvath, Thomas, Heldner, Mirjam R., Rexhaj, Emrush, Bernasconi, Corrado, Bassetti, Claudio L. A., Schmidt, Markus H.

“…IntroductionCardiovascular parameters characterizing blood pressure (BP), heart rate (HR), endothelial function and arterial stiffness predict…”
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Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans by Hukema, Renate K, Rademakers, Suzanne, Dekkers, Martijn PJ, Burghoorn, Jan, Jansen, Gert

“…Caenorhabditis elegans shows chemoattraction to 0.1–200 mM NaCl, avoidance of higher NaCl concentrations, and avoidance of otherwise attractive NaCl…”
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Signaling Proteins that Regulate NaCL Chemotaxis Responses Modulate Longevity in C. elegans by Lans, Hannes, Dekkers, Martijn P. J., Hukema, Renate K., Bialas, Nathan J., Leroux, Michel R., Jansen, Gert

“…The lifespan of the nematode Caenorhabditis elegans is regulated by sensory signals detected by the amphid neurons. In these neurons, C. elegans expresses at…”
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Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands by Teng, Michelle S, Dekkers, Martijn P J, Ng, Bee Ling, Rademakers, Suzanne, Jansen, Gert, Fraser, Andrew G, McCafferty, John

“…G-protein-coupled receptors (GPCRs) play a crucial role in many biological processes and represent a major class of drug targets. However, purification of…”
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