Search Results - "Dekant, W."

Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients by Api, A.M., Belsito, D., Bruze, M., Cadby, P., Calow, P., Dagli, M.L., Dekant, W., Ellis, G., Fryer, A.D., Fukayama, M., Griem, P., Hickey, C., Kromidas, L., Lalko, J.F., Liebler, D.C., Miyachi, Y., Politano, V.T., Renskers, K., Ritacco, G., Salvito, D., Schultz, T.W., Sipes, I.G., Smith, B., Vitale, D., Wilcox, D.K.

“…•This publication is designed to update the RIFM safety assessment process, which follows a series of decision trees.•This process incorporates advances in…”
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Correction: Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123) by Dekant, R., Bertermann, R., Serban, J., Sharma, S., Shinohara, M., Morizawa, Y., Okamoto, H., Brock, W., Dekant, W., Mally, A.

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RIFM fragrance ingredient safety assessment, acetyl cedrene, CAS Registry Number 32388-55-9 by Api, A.M., Belsito, D., Botelho, D., Bruze, M., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Date, M., Dekant, W., Deodhar, C., Fryer, A.D., Jones, L., Joshi, K., Kumar, M., Lapczynski, A., Lavelle, M., Lee, I., Liebler, D.C., Moustakas, H., Na, M., Penning, T.M., Ritacco, G., Romine, J., Sadekar, N., Schultz, T.W., Selechnik, D., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Acetyl cedrene; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123) by Dekant, R., Bertermann, R., Serban, J., Sharma, S., Shinohara, M., Morizawa, Y., Okamoto, H., Brock, W., Dekant, W., Mally, A.

“…1,1,2-Trifluoroethene (HFO-1123) is anticipated for use as a refrigerant with low global warming potential. Inhalation studies on HFO-1123 in rats indicated a…”
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Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH) by Lilienblum, W., Dekant, W., Foth, H., Gebel, T., Hengstler, J. G., Kahl, R., Kramer, P.-J., Schweinfurth, H., Wollin, K.-M.

“…During the last two decades, substantial efforts have been made towards the development and international acceptance of alternative methods to safety studies…”
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RIFM fragrance ingredient safety assessment, 4-methyl-2-pentanol, CAS registry number 108-11-2 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•4-Methyl-2-pentanol; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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Update to RIFM fragrance ingredient safety assessment, ethyl isobutyrate, CAS registry number 97-62-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Ethyl isobutyrate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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RIFM fragrance ingredient safety assessment, benzyl salicylate, CAS registry number 118-58-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Benzyl salicylate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, isoamyl salicylate, CAS Registry Number 87-20-7 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Isoamyl salicylate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•2-Butyl-4,4,6-trimethyl-1,3-dioxane; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus…”
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Update to RIFM fragrance ingredient safety assessment, isobutyl benzoate, CAS registry number 120-50-3 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Isobutyl benzoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-(1-methylethyl)-, trans-, CAS Registry Number 4625-90-5 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•1-Oxaspiro [4.5]decan-2-one, 8-(1-methylethyl)-, trans-; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints…”
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RIFM fragrance ingredient safety assessment, amyl salicylate, CAS Registry Number 2050-08-0 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Amyl salicylate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, 1-methyl-2-(1-methylpropyl)cyclohexyl acetate, CAS Registry number 72183-75-6 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•1-Methyl-2-(1-methylpropyl)cyclohexyl acetate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus…”
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RIFM fragrance ingredient safety assessment, cis-3-hexenyl benzoate, CAS Registry Number 25152-85-6 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•cis-3-Hexenyl benzoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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RIFM fragrance ingredient safety assessment, 6,8-dimethylnonan-2-ol, CAS registry number 70214-77-6 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•6,8-Dimethylnonan-2-ol; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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Update to RIFM fragrance ingredient safety assessment, methyl isovalerate, CAS Registry Number 556-24-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Methyl isovalerate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, methyl isobutyrate, CAS registry number 547-63-7 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Methyl isobutyrate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, ethyl 2-methylbutyrate, CAS Registry Number 7452-79-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Ethyl 2-methylbutyrate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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Update to RIFM fragrance ingredient safety assessment, 3-(4-methylcyclohex-3-enyl)-3-butenyl acetate, CAS registry number 6819-19-8 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•3-(4-Methylcyclohex-3-enyl)-3-butenyl acetate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus…”
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