Search Results - "Dejardin, E"
-
1
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
Published in Cell death and differentiation (01-10-2013)“…Receptor-interacting protein kinase (RIPK) 1 and RIPK3 have emerged as essential kinases mediating a regulated form of necrosis, known as necroptosis, that can…”
Get full text
Journal Article Web Resource -
2
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis
Published in Cell death and differentiation (01-12-2015)“…NF- κ B-inducing kinase (NIK) is well-known for its role in promoting p100/NF- κ B2 processing into p52, a process defined as the alternative, or…”
Get full text
Journal Article -
3
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-[kappa]B2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
Published in Oncogene (02-04-2009)“…Constitutive nuclear factor (NF)-kappaB activation in haematological malignancies is caused in several cases by loss of function mutations within the coding…”
Get full text
Journal Article -
4
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
Published in Oncogene (02-04-2009)“…Constitutive nuclear factor (NF)-κB activation in haematological malignancies is caused in several cases by loss of function mutations within the coding…”
Get full text
Journal Article Web Resource -
5
Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1
Published in Molecular cell (17-03-2006)“…We investigated the role of glycogen synthase kinase-3 (GSK-3), which is inactivated by AKT, for its role in the regulation of apoptosis. Upon IL-3 withdrawal,…”
Get full text
Journal Article Web Resource -
6
The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
Published in Immunity (Cambridge, Mass.) (01-10-2002)“…The lymphotoxin-β receptor (LTβR) plays critical roles in inflammation and lymphoid organogenesis through activation of NF-κB. In addition to activation of the…”
Get full text
Journal Article -
7
NIK promotes tissue destruction independently of the alternative NF-[kappa]B pathway through TNFR1/RIP1-induced apoptosis
Published in Cell death and differentiation (01-12-2015)“…NF-κB-inducing kinase (NIK) is well-known for its role in promoting p100/NF-κB2 processing into p52, a process defined as the alternative, or non-canonical,…”
Get full text
Journal Article -
8
RelB/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: critical roles for p100
Published in The Journal of biological chemistry (27-06-2003)“…Tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin-beta receptor (LTbetaR) signaling both play important roles in inflammatory and immune responses…”
Get full text
Journal Article Web Resource -
9
GSK3-Mediated BCL-3 Phosphorylation Modulates Its Degradation and Its Oncogenicity
Published in Molecular cell (08-10-2004)“…The oncoprotein BCL-3 is a nuclear transcription factor that activates NF-κB target genes through formation of heterocomplexes with p50 or p52. BCL-3 is…”
Get full text
Journal Article Web Resource -
10
Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines
Published in Oncogene (17-05-2001)“…The NF-kappa B transcription factor has been shown to inhibit apoptosis in several experimental systems. We therefore investigated whether the expression of…”
Get full text
Journal Article Web Resource -
11
Egr Family Members Regulate Nonlymphoid Expression of Fas Ligand, TRAIL, and Tumor Necrosis Factor during Immune Responses
Published in Molecular and Cellular Biology (01-11-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article Web Resource -
12
Further Insights in the Mechanisms of lnterleukin-1^b Stimulation of Osteoprotegerin in Osteoblast-Like Cells
Published in Journal of bone and mineral research (01-09-2007)“…The mechanisms of IL-1^b stimulation of OPG were studied in more detail. Whereas p38 and ERK activation was confirmed to be needed, NF-^KB was not necessary…”
Get full text
Journal Article -
13
The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP
Published in Haematologica (Roma) (01-08-2008)“…Department of Pathology and Groupe Interdisciplinaire de Génoprotéomique Appliqué (GIGA)- Research, CHU Sart Tilman, University of Liege, Liege, Belgium…”
Get full text
Journal Article Web Resource -
14
-
15
Regulation of NF-κB activity by IκB-related proteins in adenocarcinoma cells
Published in Oncogene (22-04-1999)“…Constitutive NF-κB activity varies widely among cancer cell lines. In this report, we studied the expression and the role of different IκB inhibitors in…”
Get full text
Journal Article -
16
The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines
Published in Biochemical pharmacology (13-01-1994)“…NF-kappa B is a pleiotropic transcription factor which controls the expression of many genes and viruses. To date, there is good evidence, but no definitive…”
Get more information
Journal Article -
17
Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells
Published in Oncogene (02-11-1995)“…Several observations have suggested that NF-kappa B transcription factors could be involved in carcinogenesis. To investigate the possibility that members of…”
Get more information
Journal Article -
18
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
Published in Oncogene (02-04-2009)“…Constitutive nuclear factor (NF)-kappaB activation in haematological malignancies is caused in several cases by loss of function mutations within the coding…”
Get full text
Journal Article -
19
Regulation of major histocompatibility complex class I expression by NF-κB-related proteins in breast cancer cells
Published in Oncogene (25-06-1998)“…Downregulation of MHC Class I antigens has been observed in many cancers and usually results from a decreased gene transcription. A reporter CAT gene dependent…”
Get full text
Journal Article -
20
Regulation of major histocompatibility complex class I expression by NF-kappaB-related proteins in breast cancer cells
Published in Oncogene (25-06-1998)“…Downregulation of MHC Class I antigens has been observed in many cancers and usually results from a decreased gene transcription. A reporter CAT gene dependent…”
Get full text
Journal Article