Search Results - "Dejam, Andrè"

Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers by Heiss, Christian, Kleinbongard, Petra, Dejam, Andrè, Perré, Sandra, Schroeter, Hagen, Sies, Helmut, Kelm, Malte

“…This study was designed to assess the effect of flavanol-rich food on the circulating pool of bioactive nitric oxide (NO) and endothelial dysfunction in…”
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Nitrite infusion in humans and nonhuman primates : Endocrine effects, pharmacokinetics, and tolerance formation by DEJAM, André, HUNTER, Christian J, SCHECHTER, Alan N, GLADWIN, Mark T, TREMONTI, Carole, PLUTA, Ryszard M, YUEN YI HON, GRIMES, George, PARTOVI, Kristine, PELLETIER, Mildred M, OLDFIELD, Edward H, CANNON, Richard O

“…The recent discovery that nitrite is an intrinsic vasodilator and signaling molecule at near-physiological concentrations has raised the possibility that…”
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Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver by Duranski, Mark R, Greer, James J M, Dejam, Andre, Jaganmohan, Sathya, Hogg, Neil, Langston, William, Patel, Rakesh P, Yet, Shaw-Fang, Wang, Xunde, Kevil, Christopher G, Gladwin, Mark T, Lefer, David J

“…Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase, nonenzymatic…”
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Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver by Duranski, Mark R., Greer, James J.M., Dejam, Andre, Jaganmohan, Sathya, Hogg, Neil, Langston, William, Patel, Rakesh P., Yet, Shaw-Fang, Wang, Xunde, Kevil, Christopher G., Gladwin, Mark T., Lefer, David J.

“…Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase, nonenzymatic…”
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Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans by Kleinbongard, Petra, Dejam, André, Lauer, Thomas, Jax, Thomas, Kerber, Stefan, Gharini, Putrika, Balzer, Jan, Zotz, Rainer B., Scharf, Rüdiger E., Willers, Reinhart, Schechter, Alan N., Feelisch, Martin, Kelm, Malte

“…A reduced nitric oxide availability is a hallmark of endothelial dysfunction occurring early in atherosclerosis. Recently, we have shown that plasma nitrite…”
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PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation by Nath, Anjali K., Ryu, Justine H., Jin, Youngnam N., Roberts, Lee D., Dejam, Andre, Gerszten, Robert E., Peterson, Randall T.

“…Virtually all organisms seek to maximize fitness by matching fuel availability with energy expenditure. In vertebrates, glucose homeostasis is central to this…”
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Role of endothelial progenitor cells and inflammatory cytokines in healing of diabetic foot ulcers by Tecilazich, Francesco, Dinh, Thanh, Pradhan-Nabzdyk, Leena, Leal, Ermelindo, Tellechea, Ana, Kafanas, Antonios, Gnardellis, Charalambos, Magargee, Mary L, Dejam, Andre, Toxavidis, Vasilis, Tigges, John C, Carvalho, Eugenia, Lyons, Thomas E, Veves, Aristidis

“…To evaluate changes in endothelial progenitor cells (EPCs) and cytokines in patients with diabetic foot ulceration (DFU) in association with wound healing. We…”
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Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals by Kleinbongard, Petra, Dejam, André, Lauer, Thomas, Rassaf, Tienush, Schindler, Achim, Picker, Olaf, Scheeren, Thomas, Gödecke, Axel, Schrader, Jürgen, Schulz, Rainer, Heusch, Gerd, Schaub, Günter A, Bryan, Nathan S, Feelisch, Martin, Kelm, Malte

“…Changes in plasma nitrite concentration in the human forearm circulation have recently been shown to reflect acute changes in endothelial nitric oxide synthase…”
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Recent methodological advances in the analysis of nitrite in the human circulation: Nitrite as a biochemical parameter of the l-arginine/NO pathway by Grau, Marijke, Hendgen-Cotta, Ulrike B., Brouzos, Paris, Drexhage, Christine, Rassaf, Tienush, Lauer, Thomas, Dejam, André, Kelm, Malte, Kleinbongard, Petra

“…Nitric oxide (NO) plays a pivotal role in the modulation of multiple physiological processes. It acts as a messenger molecule within the cardiovascular system…”
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The measurement of blood and plasma nitrite by chemiluminescence: Pitfalls and solutions by Pelletier, Mildred M., Kleinbongard, Petra, Ringwood, Lorna, Hito, Rania, Hunter, Christian J., Schechter, Alan N., Gladwin, Mark T., Dejam, André

“…There are a number of difficulties involved in the quantification of nitrite in biological systems. These difficulties result from oxidation of nitrite (within…”
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Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator by Power, Gordon G, Gladwin, Mark T, Hunter, Christian J, Dejam, André, Blood, Arlin B, Shields, Howard, Kim-Shapiro, Daniel B, Machado, Roberto F, Tarekegn, Selamawit, Mulla, Neda, Hopper, Andrew O, Schechter, Alan N

“…The blood anion nitrite contributes to hypoxic vasodilation through a heme-based, nitric oxide (NO)-generating reaction with deoxyhemoglobin and potentially…”
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Plasma Nitroso Compounds Are Decreased in Patients With Endothelial Dysfunction by Heiss, Christian, Lauer, Thomas, Dejam, André, Kleinbongard, Petra, Hamada, Sandra, Rassaf, Tienush, Matern, Simone, Feelisch, Martin, Kelm, Malte

“…Plasma Nitroso Compounds Are Decreased in Patients With Endothelial Dysfunction Christian Heiss, Thomas Lauer, André Dejam, Petra Kleinbongard, Sandra Hamada,…”
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Characterization of Erythrocytic Uptake and Release and Disposition Pathways of Nitrite, Nitrate, Methemoglobin, and Iron-Nitrosyl Hemoglobin in the Human Circulation by YUEN YI HON, HE SUN, DEJAM, André, GLADWIN, Mark T

“…Nitrite-hemoglobin reactions have been studied extensively in vitro, but there is a lack of information on the kinetics of nitrite and its metabolites in…”
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Plasma Nitrosothiols Contribute to the Systemic Vasodilator Effects of Intravenously Applied NO: Experimental and Clinical Study on the Fate of NO in Human Blood by Rassaf, Tienush, Kleinbongard, Petra, Preik, Michael, Dejam, André, Gharini, Putrika, Lauer, Thomas, Erckenbrecht, Julia, Duschin, Alexej, Schulz, Rainer, Heusch, Gerd, Feelisch, Martin, Kelm, Malte

“…ABSTRACT—Higher doses of inhaled NO exert effects beyond the pulmonary circulation. How such extrapulmonary effects can be reconciled with the presumed short…”
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Biological Activity of Nitric Oxide in the Plasmatic Compartment by Wang, Xunde, Tanus-Santos, Jose E., Reiter, Christopher D., Dejam, Andre, Shiva, Sruti, Smith, Reginald D., Hogg, Neil, Gladwin, Mark T., Ignarro, Louis J.

“…There exist reaction products of nitric oxide (NO) with blood that conserve its bioactivity and transduce an endocrine vasomotor function under certain…”
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Effects of Dietary Nitrate on Blood Pressure by Dejam, André, Hunter, Christian J, Gladwin, Mark T

“…To the Editor: Larsen and colleagues (Dec. 28 issue) 1 report that oral nitrate (NO 3 - ) can lower mean arterial blood pressure and is associated with an…”
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Fuzzy Modeling to Predict Severely Depressed Left Ventricular Ejection Fraction following Admission to the Intensive Care Unit Using Clinical Physiology by Finkelstein, Stan N., Sousa, João M. C., Vieira, Susana M., Reti, Shane R., Dejam, Andre, Salgado, Cátia M., Pereira, Rúben Duarte M. A., Celi, Leo A.

“…Left ventricular ejection fraction (LVEF) constitutes an important physiological parameter for the assessment of cardiac function, particularly in the settings…”
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Endothelial Progenitor Cell Mobilization and Increased Intravascular Nitric Oxide in Patients Undergoing Cardiac Rehabilitation by Paul, Jonathan D, Powell, Tiffany M, Thompson, Michael, Benjamin, Moshe, Rodrigo, Maria, Carlow, Andrea, Annavajjhala, Vidhya, Shiva, Sruti, Dejam, Andre, Gladwin, Mark T, McCoy, J Philip, Zalos, Gloria, Press, Beverly, Murphy, Mandy, Hill, Jonathan M, Csako, Gyorgy, Waclawiw, Myron A, Cannon, Richard O

“…PURPOSE:We investigated whether cardiac rehabilitation participation increases circulating endothelial progenitor cells (EPCs) and benefits vasculature in…”
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2-Aminoadipic acid is a biomarker for diabetes risk by Wang, Thomas J, Ngo, Debby, Psychogios, Nikolaos, Dejam, Andre, Larson, Martin G, Vasan, Ramachandran S, Ghorbani, Anahita, O'Sullivan, John, Cheng, Susan, Rhee, Eugene P, Sinha, Sumita, McCabe, Elizabeth, Fox, Caroline S, O'Donnell, Christopher J, Ho, Jennifer E, Florez, Jose C, Magnusson, Martin, Pierce, Kerry A, Souza, Amanda L, Yu, Yi, Carter, Christian, Light, Peter E, Melander, Olle, Clish, Clary B, Gerszten, Robert E

“…Improvements in metabolite-profiling techniques are providing increased breadth of coverage of the human metabolome and may highlight biomarkers and pathways…”
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Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans by SUSAN CHENG, RHEE, Eugene P, DEIK, Amy A, MAGNUSSON, Martin, FOX, Caroline S, O'DONNELL, Chistopher J, VASAN, Ramachandran S, MELANDER, Olle, CLISH, Clary B, GERSZTEN, Robert E, WANG, Thomas J, LARSON, Martin G, LEWIS, Gregory D, MCCABE, Elizabeth L, DONGXIAO SHEN, PALMA, Melinda J, ROBERTS, Lee D, DEJAM, Andre, SOUZA, Amanda L

“…Although metabolic risk factors are known to cluster in individuals who are prone to developing diabetes mellitus and cardiovascular disease, the underlying…”
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