Search Results - "Dejager, L"

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation by Dejager, L, Dendoncker, K, Eggermont, M, Souffriau, J, Van Hauwermeiren, F, Willart, M, Van Wonterghem, E, Naessens, T, Ballegeer, M, Vandevyver, S, Hammad, H, Lambrecht, B, De Bosscher, K, Grooten, J, Libert, C

“…Asthma is a heterogeneous disorder, evidenced by distinct types of inflammation resulting in different responsiveness to therapy with glucocorticoids (GCs)…”
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A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice by Yue, Zhenyu, Horton, Antony, Bravin, Monica, DeJager, Philip L, Selimi, Fekrije, Heintz, Nathaniel

“…Autophagy is a pathway for bulk degradation of subcellular constituents that is hyperactivated in many neurodegenerative conditions. It has been considered a…”
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P092 A combined role for TNFR1 and IFNAR1 in psoriasis? by Grine, L., Vandenbroucke, R., Dejager, L., Libert, C.

“…Psoriasis is a chronic inflammatory skin disease affecting 2–3 percent of the world population. The disease is mainly characterized by epidermal hyperplasia,…”
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Determining differentially expressed miRNAs and validating miRNA—target relationships using the SPRET/Ei mouse strain by Timmermans, S, Van Hauwermeiren, F, Puimège, L, Dejager, L, Van Wonterghem, E, Vanhooren, V, Mestdagh, P, Libert, C, Vandenbroucke, R. E

“…Micro RNAs (miRs) are involved in many biological processes. The challenge of identifying genes influenced by miRs is evidenced by the relatively few validated…”
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A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility by Bush, W S, McCauley, J L, DeJager, P L, Dudek, S M, Hafler, D A, Gibson, R A, Matthews, P M, Kappos, L, Naegelin, Y, Polman, C H, Hauser, S L, Oksenberg, J, Haines, J L, Ritchie, M D

“…Gene–gene interactions are proposed as an important component of the genetic architecture of complex diseases, and are just beginning to be evaluated in the…”
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O044 Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation by Vandevyver, S., Dejager, L., Bogaert, T. Van, Kleyman, A., Liu, Y., Tuckermann, J., Libert, C.

“…Glucocorticoids acting through the glucocorticoid receptor (GR) inhibit TNF-induced lethal inflammation. We demonstrate the increased TNF sensitivity of mice…”
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Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast by Treusch, Sebastian, Hamamichi, Shusei, Goodman, Jessica L., Matlack, Kent E. S., Chung, Chee Yeun, Baru, Valeriya, Shulman, Joshua M., Parrado, Antonio, Bevis, Brooke J., Valastyan, Julie S., Han, Haesun, Lindhagen-Persson, Malin, Reiman, Eric M., Evans, Denis A., Bennett, David A., Olofsson, Anders, Dejager, Philip L., Tanzi, Rudolph E., Caldwell, Kim A., Caldwell, Guy A., Lindquist, Susan

“…Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory…”
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Determining the migration of nadic acid, terephthalic acid, isophthalic acid and two oligomers from polyester food cans into food in the U.S. market by Paseiro-Cerrato, R., DeJager, L., Begley, T.H.

“…Concentrations of three monomers used in the manufacture of polyester resins for food cans, isophthalic acid (IPA), terephthalic acid (TA) and nadic acid (NA),…”
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Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation by Vandevyver, Sofie, Dejager, Lien, Van Bogaert, Tom, Kleyman, Anna, Liu, Yusen, Tuckermann, Jan, Libert, Claude

“…Glucocorticoids acting through the glucocorticoid receptor (GR) inhibit TNF-induced lethal inflammation. Here, we demonstrate that GR dimerization plays a role…”
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GWAS for executive function and processing speed suggests involvement of the CADM2 gene by Ibrahim-Verbaas, C A, Bressler, J, Schuur, M, Davies, G, Trompet, S, Smith, J A, Liu, Y, Vitart, V, Petrovic, K, Polasek, O, Zgaga, L, Fawns-Ritchie, C, Hoffmann, P, Karjalainen, J, Lahti, J, Llewellyn, D J, Schmidt, C O, Mather, K A, Chouraki, V, Resnick, S M, Rose, L M, Oldmeadow, C, Stewart, M, deJager, P L, Harris, T B, Liewald, D C, Amin, N, Coker, L H, Stegle, O, Lopez, O L, Teumer, A, Ford, I, Karbalai, N, Becker, J T, Jonsdottir, M K, Au, R, Fehrmann, R S N, Herms, S, Nalls, M, Yaffe, K, Lohman, K, van Swieten, J C, Kardia, S L R, Knopman, D S, Meeks, W M, Heiss, G, Holliday, E G, Tanaka, T, Stott, D J, Wang, J, Ridker, P, Pattie, A, Starr, J M, Hocking, L J, Armstrong, N J, McLachlan, S, Shulman, J M, Eiriksdottir, G, Scott, R J, Kochan, N A, Palotie, A, Hsieh, Y-C, Penman, A, Gottesman, R F, Yu, L, Beiser, A, Garcia, M, Rotter, J I, Slagboom, P E, Westendorp, R G J, Buckley, B M, Wolf, P A, Uitterlinden, A G, Grabe, H J, Bandinelli, S, Chasman, D I, Grodstein, F, Räikkönen, K, Porteous, D J, Price, J F, Sachdev, P S, Ferrucci, L, Attia, J R, Rudan, I, Hayward, C, Wright, A F, Wilson, J F, Cichon, S, Schmidt, H, Ding, J, de Craen, A J M, Fornage, M, Bennett, D A, Deary, I J, Ikram, M A, Launer, L J, Fitzpatrick, A L, Seshadri, S, van Duijn, C M, Mosley, T H

“…To identify common variants contributing to normal variation in two specific domains of cognitive functioning, we conducted a genome-wide association study…”
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The CD33 Alzheimer's disease locus: Correcting the functional consequences of the risk allele using small molecules by Ryan, Katie J, Boyd, Justin D, Laversenne, Vanessa, Chan, Gail, Winn, Phoebe, Frangieh, Michael, Cimpean, Maria, Mchenry, Alison, Chibnik, Lori B, Glicksman, Marcie A, Dejager, Philip L, Bradshaw, Elizabeth M

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Thirty years of Mus spretus : a promising future by Dejager, Lien, Libert, Claude, Montagutelli, Xavier

“…Extensive genetic polymorphisms in Mus spretus have ensured its widespread use in many areas of genetics. With the recent increase in the number of single…”
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Pharmacological Inhibition of Type I Interferon Signaling Protects Mice Against Lethal Sepsis by Dejager, Lien, Vandevyver, Sofie, Ballegeer, Marlies, Van Wonterghem, Elien, An, Ling-Ling, Riggs, Jeffrey, Kolbeck, Roland, Libert, Claude

“…Current research on new therapeutic strategies for sepsis uses different animal models, such as the lipopolysaccharide-induced endotoxemia model and the cecal…”
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In vitro characterization of the ADAMTS-5 specific nanobody® M6495 by Werkmann, D., Buyse, M.-A., Dejager, L., Cornelis, S., Thudium, C.S., Karsdal, M.A., Ladel, C., Guehring, H., Michaelis, M., Lindemann, S.

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A Novel Protein Complex Linking the δ2 Glutamate Receptor and Autophagy by Yue, Zhenyu, Horton, Antony, Bravin, Monica, DeJager, Philip L., Selimi, Fekrije, Heintz, Nathaniel

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Electric field exposure and evidence of stress in mice by de Bruyn, L, de Jager, L

“…The effect of stress induced by an electric field on the adrenal gland cortex of mice was examined by means of corticosterone serum assay and evaluation of the…”
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Antiidiotype antibodies in cancer patients receiving monoclonal antibody to carcinoembryonic antigen by TRAUB, U. C, DEJAGER, R. L, PRIMUS, F. J, LOSMAN, M, GOLDENBERG, D. M

“…The initial 10 patients of a Phase I clinical trial involving multiple injections of murine monoclonal anti-carcinoembryonic antigen (CEA) antibody, NP-2, were…”
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A phase I randomized study of subcutaneous adjuvant IL-2 in combination with an autologous tumor vaccine in patients with advanced renal cell carcinoma by Fenton, R G, Steis, R G, Madara, K, Zea, A H, Ochoa, A C, Janik, J E, Smith, 2nd, J W, Gause, B L, Sharfman, W H, Urba, W J, Hanna, M G, DeJager, R L, Coyne, M X, Crouch, R D, Gray, P, Beveridge, J, Creekmore, S P, Holmlund, J, Curti, B D, Sznol, M, Longo, D L

“…We performed a prospective, randomized study to determine whether subcutaneous administration of interleukin-2 (IL-2) in combination with an autologous renal…”
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Neutralizing TNF[alpha] restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation by Dejager, L, Dendoncker, K, Eggermont, M, Souffriau, J, Van Hauwermeiren, F, Willart, M, Van Wonterghem, E, Naessens, T, Ballegeer, M, Vandevyver, S, Hammad, H, Lambrecht, B, De Bosscher, K, Grooten, J, Libert, C

“…Asthma is a heterogeneous disorder, evidenced by distinct types of inflammation resulting in different responsiveness to therapy with glucocorticoids (GCs)…”
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Preoperative Scintigraphy and Operative Probe Scintimetry of Colorectal Carcinoma Using Technetium-99m-88BV59 by Moffat, Frederick L., Jr, Vargas-Cuba, Ruben D, Serafini, Aldo N, Jabir, A.M, Sfakianakis, George N, Sittler, Scott Y, Robinson, David S, Crichton, Virginia Z, Subramanian, Ramaswamy, Murray, James H, Klein, Jerry L, Hanna, Michael G., Jr, DeJager, Robert L

“…We report a pilot study of radioimmunoscintigraphy (RIS) and operative gamma probe scintimetry (OPS) using a 99mTc-labeled anti-cytokeratin human monoclonal…”
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