Search Results - "Deiter, Fred"
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Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction
Published in Frontiers in immunology (07-10-2021)“…Advanced donor age is a risk factor for poor survival following lung transplantation. However, recent work identifying epigenetic determinants of aging has…”
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Human galectin-9 potently enhances SARS-CoV-2 replication and inflammation in airway epithelial cells
Published in Journal of molecular cell biology (03-08-2023)“…Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused a global economic and health crisis. Recently, plasma levels of…”
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A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells
Published in Communications biology (22-04-2024)“…The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need for innovative therapies with high genetic barriers to resistance…”
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Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature
Published in American journal of transplantation (01-01-2021)“…Chronic lung allograft dysfunction (CLAD) is the major barrier to long‐term survival following lung transplantation, and new mechanistic biomarkers are needed…”
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Rapid molecular detection of airway pathogens in lung transplant recipients
Published in Transplant infectious disease (01-08-2021)“…Background Airway infections are difficult to distinguish from acute rejection in lung transplant recipients. Traditional culture techniques take time that may…”
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Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction‐free survival
Published in Clinical transplantation (01-06-2022)“…Background Lung transplant recipients undergo bronchoalveolar lavage (BAL) to detect antecedents of chronic lung allograft dysfunction (CLAD), but routine…”
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Biofire pneumonia panel in lung donors: faster detection but limited pathogens
Published in Transplant infectious disease (01-08-2023)“…Background Culture of bronchoalveolar lavage (BAL) specimens takes time to report. We tested whether a molecular diagnostic test could accelerate donor lung…”
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