Search Results - "Deist, Timo M"
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TESS3: fast inference of spatial population structure and genome scans for selection
Published in Molecular ecology resources (01-03-2016)“…Geography and landscape are important determinants of genetic variation in natural populations, and several ancestry estimation methods have been proposed to…”
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Radiomics: the bridge between medical imaging and personalized medicine
Published in Nature reviews. Clinical oncology (01-12-2017)“…Key Points Radiomics is becoming increasingly more important in medical imaging The explosion of medical imaging data creates an environment ideal for…”
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Distributed learning: Developing a predictive model based on data from multiple hospitals without data leaving the hospital – A real life proof of concept
Published in Radiotherapy and oncology (01-12-2016)“…Abstract Purpose One of the major hurdles in enabling personalized medicine is obtaining sufficient patient data to feed into predictive models. Combining data…”
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Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers
Published in Medical physics (Lancaster) (01-07-2018)“…Purpose Machine learning classification algorithms (classifiers) for prediction of treatment response are becoming more popular in radiotherapy literature…”
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Infrastructure and distributed learning methodology for privacy-preserving multi-centric rapid learning health care: euroCAT
Published in Clinical and translational radiation oncology (01-06-2017)“…[Display omitted] •Developed and implemented IT infrastructure in 5 radiation clinics across 3 countries.•Proof-of-principle for ‘big data’ infrastructure and…”
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Simulation-assisted machine learning
Published in Bioinformatics (15-10-2019)“…Abstract Motivation In a predictive modeling setting, if sufficient details of the system behavior are known, one can build and use a simulation for making…”
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Developing and Validating a Survival Prediction Model for NSCLC Patients Through Distributed Learning Across 3 Countries
Published in International journal of radiation oncology, biology, physics (01-10-2017)“…Tools for survival prediction for non-small cell lung cancer (NSCLC) patients treated with chemoradiation or radiation therapy are of limited quality. In this…”
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Distributed learning on 20 000+ lung cancer patients – The Personal Health Train
Published in Radiotherapy and oncology (01-03-2020)“…•Machine learning without sharing patient data, quickly and at scale.•Connecting 8 oncology institutes from 5 countries.•Survival prediction modelling on…”
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Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer
Published in Scientific reports (11-03-2020)“…A major challenge in radiomics is assembling data from multiple centers. Sharing data between hospitals is restricted by legal and ethical regulations…”
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Decision support systems for personalized and participative radiation oncology
Published in Advanced drug delivery reviews (15-01-2017)“…A paradigm shift from current population based medicine to personalized and participative medicine is underway. This transition is being supported by the…”
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Distributed radiomics as a signature validation study using the Personal Health Train infrastructure
Published in Scientific data (22-10-2019)“…Prediction modelling with radiomics is a rapidly developing research topic that requires access to vast amounts of imaging data. Methods that work on…”
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Modern clinical research: How rapid learning health care and cohort multiple randomised clinical trials complement traditional evidence based medicine
Published in Acta oncologica (21-10-2015)“…Trials are vital in informing routine clinical care; however, current designs have major deficiencies. An overview of the various challenges that face modern…”
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Developing and validating a survival prediction model for NSCLC patients through distributed learning across three countries
Published in International journal of radiation oncology, biology, physics (2017)“…Abstract Purpose Tools for survival prediction for non-small cell lung cancer (NSCLC) patients treated with (chemo)radiotherapy are of limited quality. In this…”
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Multi-objective Optimization by Uncrowded Hypervolume Gradient Ascent
Published 22-02-2021“…B\"ack T. et al. (eds) Parallel Problem Solving from Nature - PPSN XVI. PPSN 2020. Lecture Notes in Computer Science, vol 12270. Springer, Cham Evolutionary…”
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Multi-Objective Learning to Predict Pareto Fronts Using Hypervolume Maximization
Published 08-02-2021“…Real-world problems are often multi-objective with decision-makers unable to specify a priori which trade-off between the conflicting objectives is preferable…”
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High-dose-rate prostate brachytherapy inverse planning on dose-volume criteria by simulated annealing
Published 28-03-2017“…Physics in Medicine and Biology, 61(3), 1155-1170, 2016 High-dose-rate brachytherapy is a tumor treatment method where a highly radioactive source is brought…”
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Identifying Properties of Real-World Optimisation Problems through a Questionnaire
Published 11-11-2020“…Optimisation algorithms are commonly compared on benchmarks to get insight into performance differences. However, it is not clear how closely benchmarks match…”
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Simulation assisted machine learning
Published 12-08-2019“…Motivation: In a predictive modeling setting, if sufficient details of the system behavior are known, one can build and use a simulation for making…”
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Towards Realistic Optimization Benchmarks: A Questionnaire on the Properties of Real-World Problems
Published 14-04-2020“…Benchmarks are a useful tool for empirical performance comparisons. However, one of the main shortcomings of existing benchmarks is that it remains largely…”
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