Search Results - "Dehouck, Lucie"

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells by Cecchelli, Romeo, Aday, Sezin, Sevin, Emmanuel, Almeida, Catarina, Culot, Maxime, Dehouck, Lucie, Coisne, Caroline, Engelhardt, Britta, Dehouck, Marie-Pierre, Ferreira, Lino

“…The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal…”
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A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow by Mossu, Adrien, Rosito, Maria, Khire, Tejas, Li Chung, Hung, Nishihara, Hideaki, Gruber, Isabelle, Luke, Emma, Dehouck, Lucie, Sallusto, Federica, Gosselet, Fabien, McGrath, James L, Engelhardt, Britta

“…Here we report on the development of a breakthrough microfluidic human in vitro cerebrovascular barrier (CVB) model featuring stem cell-derived brain-like…”
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A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters by Sevin, Emmanuel, Dehouck, Lucie, Versele, Romain, Culot, Maxime, Gosselet, Fabien

“…Characterizing interaction of newly synthetized molecules with efflux pumps remains essential to improve their efficacy and safety. Caco-2 cell line cultivated…”
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Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier by Clé, Marion, Desmetz, Caroline, Barthelemy, Jonathan, Martin, Marie-France, Constant, Orianne, Maarifi, Ghizlane, Foulongne, Vincent, Bolloré, Karine, Glasson, Yaël, De Bock, Frédéric, Blaquiere, Marine, Dehouck, Lucie, Pirot, Nelly, Tuaillon, Edouard, Nisole, Sébastien, Najioullah, Fatiha, Van de Perre, Philippe, Cabié, André, Marchi, Nicola, Gosselet, Fabien, Simonin, Yannick, Salinas, Sara

“…Zika virus (ZIKV) can be associated with neurological impairment in children and adults. To reach the central nervous system, viruses have to cross the…”
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Contribution of brain pericytes in blood-brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells by Heymans, Marjolein, Figueiredo, Ricardo, Dehouck, Lucie, Francisco, David, Sano, Yasuteru, Shimizu, Fumitaka, Kanda, Takashi, Bruggmann, Rémy, Engelhardt, Britta, Winter, Peter, Gosselet, Fabien, Culot, Maxime

“…Formation, maintenance, and repair of the blood-brain barrier (BBB) are critical for central nervous system homeostasis. The interaction of endothelial cells…”
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Transient blood-brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity by Sharabi, Shirley, Bresler, Yael, Ravid, Orly, Shemesh, Chen, Atrakchi, Dana, Schnaider-Beeri, Michal, Gosselet, Fabien, Dehouck, Lucie, Last, David, Guez, David, Daniels, Dianne, Mardor, Yael, Cooper, Itzik

“…The blood-brain barrier (BBB) is limiting transcellular and paracellular movement of molecules and cells, controls molecular traffic, and keeps out toxins…”
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Time-Dependent Internalization of Polymer-Coated Silica Nanoparticles in Brain Endothelial Cells and Morphological and Functional Effects on the Blood-Brain Barrier by Bittner, Aniela, Gosselet, Fabien, Sevin, Emmanuel, Dehouck, Lucie, Ducray, Angélique D, Gaschen, Véronique, Stoffel, Michael H, Cho, Hansang, Mevissen, Meike

“…Nanoparticle (NP)-assisted procedures including laser tissue soldering (LTS) offer advantages compared to conventional microsuturing, especially in the brain…”
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Enterovirus A71 crosses a human blood-brain barrier model through infected immune cells by Gaume, Léa, Chabrolles, Hélène, Bisseux, Maxime, Lopez-Coqueiro, Igor, Dehouck, Lucie, Mirand, Audrey, Henquell, Cécile, Gosselet, Fabien, Archimbaud, Christine, Bailly, Jean-Luc

“…Enterovirus A71 (EV-A71) is associated with neurological conditions such as acute meningitis and encephalitis. The virus is detected in the bloodstream, and…”
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Erratum for Gaume et al., "Enterovirus A71 crosses a human blood-brain barrier model through infected immune cells" by Gaume, Léa, Chabrolles, Hélène, Bisseux, Maxime, Coqueiro, Igor Lopes, Dehouck, Lucie, Mirand, Audrey, Henquell, Cécile, Gosselet, Fabien, Archimbaud, Christine, Bailly, Jean-Luc

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Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties by Ravid, Orly, Elhaik Goldman, Shirin, Macheto, David, Bresler, Yael, De Oliveira, Raquel Ines, Liraz-Zaltsman, Sigal, Gosselet, Fabien, Dehouck, Lucie, Beeri, Michal Schnaider, Cooper, Itzik

“…Organophosphorus compounds (OPs) are highly toxic chemicals widely used as pesticides (e.g., paraoxon (PX)- the active metabolite of the insecticide parathion)…”
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Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells by Dehouck, Marie-Pierre, Tachikawa, Masanori, Hoshi, Yutaro, Omori, Kotaro, Maurage, Claude-Alain, Strecker, Guillaume, Dehouck, Lucie, Boucau, Marie-Christine, Uchida, Yasuo, Gosselet, Fabien, Terasaki, Tetsuya, Karamanos, Yannis

“…We previously developed an in vitro model of the human blood-brain barrier (BBB) based on the use of endothelial cells derived from CD34 -hematopoietic stem…”
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Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes by Vandenhaute, Elodie, Dehouck, Lucie, Boucau, Marie-Christine, Sevin, Emmanuel, Uzbekov, Rustem, Tardivel, Meryem, Gosselet, Fabien, Fenart, Laurence, Cecchelli, Romeo, Dehouck, Marie-Pierre

“…The blood-brain barrier (BBB) is a dynamic cellular complex that is responsible for the maintenance of brain homeostasis. To understand the BBB's key cellular…”
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Mouse syngenic in vitro blood-brain barrier model : a new tool to examine inflammatory events in cerebral endothelium by COISNE, Caroline, DEHOUCK, Lucie, DEHOUCK, Bénédicte, FAVEEUW, Christelle, DELPLACE, Yannick, MILLER, Florence, LANDRY, Christophe, MORISSETTE, Céline, FENART, Laurence, CECCHELLI, Romeo, TREMBLAY, Patrick

“…Although cerebral endothelium disturbance is commonly observed in central nervous system (CNS) inflammatory pathologies, neither the cause of this phenomenon…”
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ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells by Cicero, Julien, Trouvilliez, Sarah, Palma, Martine, Ternier, Gaetan, Decoster, Laurine, Happernegg, Eloise, Barois, Nicolas, Van Outryve, Alexandre, Dehouck, Lucie, Bourette, Roland P, Adriaenssens, Eric, Lagadec, Chann, Tarhan, Cagatay Mehmet, Collard, Dominique, Souguir, Zied, Vandenhaute, Elodie, Maubon, Grégory, Sipieter, François, Borghi, Nicolas, Shimizu, Fumitaka, Kanda, Takashi, Giacobini, Paolo, Gosselet, Fabien, Maubon, Nathalie, Le Bourhis, Xuefen, Van Seuningen, Isabelle, Mysiorek, Caroline, Toillon, Robert-Alain

“…Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life,…”
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Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier by Mysiorek, Caroline, Culot, Maxime, Dehouck, Lucie, Derudas, Bruno, Staels, Bart, Bordet, Régis, Cecchelli, Roméo, Fenart, Laurence, Berezowski, Vincent

“…That promising neuroprotectants failed to demonstrate benefit against stroke highlights the great difficulties to translate preclinical pharmacological effects…”
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Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro by Vandenhaute, Elodie, Culot, Maxime, Gosselet, Fabien, Dehouck, Lucie, Godfraind, Catherine, Franck, Michel, Plouët, Jean, Cecchelli, Roméo, Dehouck, Marie-Pierre, Ruchoux, Marie-Magdeleine

“…The function of pericytes remains questionable but with improved cultured technique and the use of genetically modified animals, it has become increasingly…”
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Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli by Coisne, Caroline, Faveeuw, Christelle, Delplace, Yannick, Dehouck, Lucie, Miller, Florence, Cecchelli, Roméo, Dehouck, Bénédicte

“…Increased lymphocyte trafficking across blood–brain barrier (BBB) is a prominent and early event in inflammatory and immune-mediated CNS diseases. The adhesion…”
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25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro by Loiola, Rodrigo Azevedo, Nguyen, Cindy, Dib, Shiraz, Saint-Pol, Julien, Dehouck, Lucie, Sevin, Emmanuel, Naudot, Marie, Landry, Christophe, Pahnke, Jens, Pot, Caroline, Gosselet, Fabien

“…Intracellular cholesterol metabolism is regulated by the SREBP-2 and LXR signaling pathways. The effects of inflammation on these molecular mechanisms remain…”
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25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro by Loiola, Rodrigo Azevedo, Nguyen, Cindy, Dib, Shiraz, Saint-Pol, Julien, Dehouck, Lucie, Sevin, Emmanuel, Naudot, Marie, Landry, Christophe, Pahnke, Jens, Pot, Caroline, Gosselet, Fabien

“…Intracellular cholesterol metabolism is regulated by the SREBP-2 and LXR signaling pathways. The effects of inflammation on these molecular mechanisms remain…”
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Maternal exposure to pesticides induces perturbations in the gut microbiota and blood–brain barrier of dams and the progeny, prevented by a prebiotic by Abou Diwan, Maria, Djekkoun, Narimane, Boucau, Marie-Christine, Corona, Aurélie, Dehouck, Lucie, Biendo, Maurice, Gosselet, Fabien, Bach, Véronique, Candela, Pietra, Khorsi-Cauet, Hafida

“…Exposure to pesticide residues during the first 1000 days of life can disrupt body homeostasis and contribute to chronic metabolic diseases. Perinatal…”
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