Search Results - "Dehigaspitiya, Dilani Chathurika"
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1
Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors
Published in Bioorganic & medicinal chemistry (01-09-2013)“…Probes for use in time-resolved fluorescence competitive binding assays at melanocortin receptors based on the parental ligands MSH(4), MSH(7), and NDP-α-MSH…”
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Journal Article -
2
Synthesis and bioactivity of MSH4 oligomers prepared by an A 2 + B 2 strategy
Published in Tetrahedron letters (03-06-2015)“…Oligomers incorporating the tetrapeptide MSH4, the minimum active sequence of melanocyte stimulating hormone, were synthesized by an A + B strategy involving…”
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Journal Article -
3
Synthesis and bioactivity of MSH4 oligomers prepared by an A2+B2 strategy
Published in Tetrahedron letters (03-06-2015)“…[Display omitted] Oligomers incorporating the tetrapeptide MSH4, the minimum active sequence of melanocyte stimulating hormone, were synthesized by an A2+B2…”
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Journal Article -
4
Linear scaffolds for multivalent targeting of melanocortin receptors
Published in Organic & biomolecular chemistry (01-01-2015)“…Molecules bearing one, two, three, or four copies of the tetrapeptide His-dPhe-Arg-Trp were attached to scaffolds based on ethylene glycol, glycerol, and…”
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Journal Article -
5
Design, synthesis, and testing of multivalent compounds targeted to melanocortin receptors
Published 01-01-2014“…Our focus is on developing non-invasive molecular imaging reagents, which target human cancers that presently are difficult to detect, such as melanoma. We…”
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Dissertation -
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Design, synthesis, and testing of multivalent compounds targeted to melanocortin receptors
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Dissertation