Search Results - "Deharvengt, Sophie J."

The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition by Stan, Radu V., Tse, Dan, Deharvengt, Sophie J., Smits, Nicole C., Xu, Yan, Luciano, Marcus R., McGarry, Caitlin L., Buitendijk, Maarten, Nemani, Krishnamurthy V., Elgueta, Raul, Kobayashi, Takashi, Shipman, Samantha L., Moodie, Karen L., Daghlian, Charles P., Ernst, Patricia A., Lee, Hong-Kee, Suriawinata, Arief A., Schned, Alan R., Longnecker, Daniel S., Fiering, Steven N., Noelle, Randolph J., Gimi, Barjor, Shworak, Nicholas W., Carrière, Catherine

“…Fenestral and stomatal diaphragms are endothelial subcellular structures of unknown function that form on organelles implicated in vascular permeability:…”
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Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo by Davis, Scott C., Samkoe, Kimberley S., Tichauer, Kenneth M., Sexton, Kristian J., Gunn, Jason R., Deharvengt, Sophie J., Hasan, Tayyaba, Pogue, Brian W.

“…The up-regulation of cell surface receptors has become a central focus in personalized cancer treatment; however, because of the complex nature of contrast…”
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Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge by Al-Turkmani, M. Rabie, Suriawinata, Michael A., Deharvengt, Sophie J., Green, Donald C., Black, Candice C., Shirai, Keisuke, Dragnev, Konstantin H., Tsongalis, Gregory J.

“…Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC) patients predicts…”
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Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells by Tkachenko, Eugene, Tse, Dan, Sideleva, Olga, Deharvengt, Sophie J, Luciano, Marcus R, Xu, Yan, McGarry, Caitlin L, Chidlow, John, Pilch, Paul F, Sessa, William C, Toomre, Derek K, Stan, Radu V

“…PV1 protein is an essential component of stomatal and fenestral diaphragms, which are formed at the plasma membrane of endothelial cells (ECs), on structures…”
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Internal Standards for Limit Controls and Absolute Abundance Measurement of Oncogenic Fusions and Mutations by Morrison, Tom, Lo, Bryan, Deharvengt, Sophie J, Lazaridis, Nick, Tsongalis, Gregory J

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CD10 and p63 expression in a sarcomatoid undifferentiated melanoma: A cautionary (and molecularly annotated) tale by Lefferts, Joel A, Loehrer, Andrew P., Yan, Shaofeng, Green, Donald C., Deharvengt, Sophie J., LeBlanc, Robert E.

“…Undifferentiated melanoma should be considered in the differential diagnosis of sarcomatoid cutaneous malignancies to ensure that patients receive the correct…”
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Utility of Retrospective Molecular Analysis in Diagnostically Challenging Mesenchymal Neoplasms by Mindiola Romero, Andres E., Tafe, Laura J., Green, Donald C., Deharvengt, Sophie J., Winnick, Kimberly N., Tsongalis, Gregory J., Baker, Michael L., Linos, Konstantinos, Levy, Joshua J., Kerr, Darcy A.

“…Introduction: Molecular analysis plays a growing role in the diagnosis of mesenchymal neoplasms. The aim of this study was to retrospectively apply broad,…”
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Endothelial Plasmalemma Vesicle-Associated Protein Regulates the Homeostasis of Splenic Immature B Cells and B-1 B Cells by Elgueta, Raul, Tse, Dan, Deharvengt, Sophie J, Luciano, Marcus R, Carriere, Catherine, Noelle, Randolph J, Stan, Radu V

“…Plasmalemma vesicle-associated protein (Plvap) is an endothelial protein with roles in endothelial diaphragm formation and maintenance of basal vascular…”
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Primary Cutaneous Adenomyoepithelioma Ex Spiradenoma With Malignant Histologic Features, Epithelial-Myoepithelial Carcinoma Type: A First Case Report With Molecular Studies by Tran, Tien Anh N., Bridge, Julia A., Deharvengt, Sophie J., Green, Donald C., Linos, Konstantinos

“…Adenomyoepithelioma is an extremely rare primary cutaneous neoplasm. Although there is ample evidence on the existence of malignant adenomyoepithelioma in the…”
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Implementation of a pharmacist-guided pharmacogenomics dosing service at a rural NCI-designated comprehensive cancer center by Green, Jenna K, Hackett, Laura J, Green, Donald C, Deharvengt, Sophie J, Brooks, Gabriel A, Khan, Wahab A, Tsongalis, Gregory J, Lewis, Lionel D, Shah, Parth S

“…The goal of pharmacogenetic testing is to identify genetic variants with significant implications on drug safety and efficacy. Several professional…”
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Variant allele frequencies do not correlate well with myeloblast counts in a clinically validated gene sequencing panel for routine acute myeloid leukemia workup by Toth, Laura N., Green, Donald, Peterson, Jason, Deharvengt, Sophie J., de Abreu, Francine B., Loo, Eric Y.

“…Next generation sequencing (NGS) has introduced new types of data, such as variant allele frequencies (VAFs), into the workup of acute myeloid leukemias (AML)…”
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Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma by Shee, Kevin, Chambers, Meagan, Hughes, Edward G., Almiron, Damian A., Deharvengt, Sophie J., Green, Donald, Lefferts, Joel A., Andrew, Angeline S., Hickey, William F., Tsongalis, Gregory J.

“…Introduction Recent molecular characterization of gliomas has uncovered somatic gene variation and DNA methylation changes that are associated with etiology,…”
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Identifying Associations between Somatic Mutations and Clinicopathologic Findings in Lung Cancer Pathology Reports by Kumar, Nishant, Tafe, Laura J, Higgins, John H, Peterson, Jason D, de Abreu, Francise Blumental, Deharvengt, Sophie J, Tsongalis, Gregory J, Amos, Christopher I, Hassanpour, Saeed

“…We aim to build an informatics methodology capable of identifying statistically significant associations between the clinical findings of non-small cell lung…”
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Mutations in Plasmalemma Vesicle Associated Protein Result in Sieving Protein-Losing Enteropathy Characterized by Hypoproteinemia, Hypoalbuminemia, and Hypertriglyceridemia by Elkadri, Abdul, Thoeni, Cornelia, Deharvengt, Sophie J, Murchie, Ryan, Guo, Conghui, Stavropoulos, James D, Marshall, Christian R, Wales, Paul, Bandsma, Robert H.J, Cutz, Ernest, Roifman, Chaim M, Chitayat, David, Avitzur, Yaron, Stan, Radu V, Muise, Aleixo M

“…Background & Aims Severe intestinal diseases observed in very young children are often the result of monogenic defects. We used whole-exome sequencing (WES) to…”
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Tumor Endothelial Marker Imaging in Melanomas Using Dual-Tracer Fluorescence Molecular Imaging by Tichauer, Kenneth M., Deharvengt, Sophie J., Samkoe, Kimberley S., Gunn, Jason R., Bosenberg, Marcus W., Turk, Mary-Jo, Hasan, Tayyaba, Stan, Radu V., Pogue, Brian W.

“…Purpose Cancer-specific endothelial markers available for intravascular binding are promising targets for new molecular therapies. In this study, a molecular…”
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PV1 down‐regulation via shRNA inhibits the growth of pancreatic adenocarcinoma xenografts by Deharvengt, Sophie J., Tse, Dan, Sideleva, Olga, McGarry, Caitlin, Gunn, Jason R., Longnecker, Daniel S., Carriere, Catherine, Stan, Radu V.

“…PV1 is an endothelial‐specific protein with structural roles in the formation of diaphragms in endothelial cells of normal vessels. PV1 is also highly…”
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Implementation of Multicolor Melt Curve Analysis for High-Risk Human Papilloma Virus Detection in Low- and Middle-Income Countries: A Pilot Study for Expanded Cervical Cancer Screening in Honduras by Turner, Scott A, Deharvengt, Sophie J, Lyons, Kathleen Doyle, Espinal, Jorge Arturo Plata, LaRochelle, Ethan P M, Bejarano, Suyapa, Kennedy, Linda, Tsongalis, Gregory J

“…Cervical cancer is a leading cause of cancer-related mortality in low- and middle-income countries (LMICs) and screening in LMICs is extremely limited. We…”
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Use of Biosynthetic Controls as Performance Standards for Next-Generation Sequencing Assays of Somatic Tumors: A Multilaboratory Study by De Abreu, Francine B, Peterson, Jason D, Deharvengt, Sophie J, Daber, Robert, Sarsani, Vishal K, Spotlow, Vanessa, Harrington, Robin D, Lih, Chih-Jian, Williams, P Mickey, Bouk, Courtney H, Konigshofer, Yves, Huang, Catherine, Anekella, Bharathi, Davis, Lorn, Garlick, Russell K, Ferreira-Gonzalez, Andrea, Dumur, Catherine I, Fernandes, Helen, Haralampu, Stephen, Tsongalis, Gregory J

“…BACKGROUNDNext-generation sequencing (NGS) assays are highly complex tests that can vary substantially in both their design and intended application. Despite…”
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Association of plasma uracil concentration with 5-FU pharmacokinetics, dose-limiting toxicity, and DPYD genotype in patients with gastrointestinal cancer by Brooks, Gabriel A., Ness, Dylan B., Hourdequin, Kathryn Cunningham, Ripple, Gregory H., Amin, Manik A., Lord-Halvorson, Sierra, Khan, Wahab A., Deharvengt, Sophie J., Dragnev, Konstantin H., Tsongalis, Gregory J., Zhao, Wenyan, Tosteson, Tor D., Lewis, Lionel D

“…751 Background: Plasma uracil concentration >16 ng/mL is used in some countries as a screening test for DPD deficiency. We conducted this exploratory study to…”
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Use of Anchored Multiplex PCR Enrichment for Detection of Gene Fusions in Solid Tumors by Next Generation Sequencing by Green, Donald C, Deharvengt, Sophie J, de Abreu, Francine B, Steinmetz, Heather B, Peterson, Jason D, Tsongalis, Gregory J

“…Abstract only…”
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