Search Results - "Dehaen, W"

QSAR-derived affinity fingerprints (part 1): fingerprint construction and modeling performance for similarity searching, bioactivity classification and scaffold hopping by Škuta, C., Cortés-Ciriano, I., Dehaen, W., Kříž, P., van Westen, G. J. P., Tetko, I. V., Bender, A., Svozil, D.

“…An affinity fingerprint is the vector consisting of compound’s affinity or potency against the reference panel of protein targets. Here, we present the QAFFP…”
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Exploring of protein – protein interactions at the solid – aqueous interface by means of contact angle measurements by Grabowska, I., Dehaen, W., Radecka, H., Radecki, J.

“…[Display omitted] •His6-VC1-RAGE domain was bond to Cu(II) or Ni(II) complexes with dipyrromethene.•The contact angle method was suitable for study of…”
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Indolo[3,2- b]carbazole-based functional derivatives as materials for light emitting diodes by Lengvinaite, S., Grazulevicius, J.V., Grigalevicius, S., Gu, R., Dehaen, W., Jankauskas, V., Zhang, B., Xie, Z.

“…Derivatives of indolo[3,2- b]carbazole containing reactive oxetanyl groups were characterized using 1H NMR, IR spectroscopy and mass spectrometry. The…”
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Enhanced Performance of an Affinity Biosensor Interface Based on Mixed Self-Assembled Monolayers of Thiols on Gold by Frederix, F., Bonroy, K., Laureyn, W., Reekmans, G., Campitelli, A., Dehaen, W., Maes, G.

“…An affinity biosensor interface of a biosensor is the interface between the sample and the transducer surface and is therefore of the utmost importance for the…”
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Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo by Arckens, L., Dehaen, W., Moons, Lieve, Van Wonterghem, E., Balusu, S., Dera, R., Vandenbroucke, Roosmarijn E., Aerts, J., Libert, Claude

“…A hydroxypyrone-based matrix metalloproteinase (MMP) inhibitor was synthesized and assayed for its inhibitory capacity towards a panel of ten different MMPs…”
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2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents by Balzarini, J., Thomas, J., Liekens, S., Noppen, S., Dehaen, W., Romagnoli, R.

“…Summary Cytostatic agents often do not discriminate in their cytostatic potential between different tumor cell types in vitro. In this study, several…”
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Hole-transporting glass-forming indolo[3,2- b]carbazole-based diepoxy monomer and polymers by Kirkus, M., Grazulevicius, J.V., Grigalevicius, S., Gu, R., Dehaen, W., Jankauskas, V.

“…Hole-transporting indolo[3,2- b]carbazole-based diepoxy monomer and polymers are reported. The polymers were prepared by polyaddition reaction of indolo[3,2-…”
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Indolyl-substituted carbazole derivatives: Electrochemical and photophysical properties and computational studies by Keruckiene, R., Peckus, D., Tamulevicius, T., Tamulevicius, S., Daniels, M., Dehaen, W., Simokaitiene, J., Grazulevicius, J. V.

“…A series of new indolyl-substituted carbazole derivatives were synthesized and their properties were studied. All the final compounds form molecular glasses…”
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Systematic study of interaction of the neutral form of anilines with undecylcalix[4]resorcinarene derivatives by means of potentiometry by Poduval, R., Kurzątkowska, K., Stobiecka, M., Dehaen, W.F.A., Dehaen, W., Radecka, H., Radecki, J.

“…The elucidation of the mechanism of potentiometric signals generation by liquid membrane electrodes incorporating undecylcalix[4]resorcinarene derivatives upon…”
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Sterically encumbered triarylcorroles from aryldipyrromethanes and aromatic aldehydes by Asokan, C.V, Smeets, S, Dehaen, W

“…A two-step synthesis of corroles from dipyrromethanes and aromatic aldehydes has been achieved. Acid-catalyzed [2+2] condensation of…”
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Antihyperglycemic Activity of Extracts from Boldoa purpurascens Leaves in Alloxan-Induced Diabetic Rats by González Mosquera, D. M., Hernandez Ortega, Y., By, B., Vicet Muro, L., Saucedo Hernandez, Y., Grau Ábalos, R., Dehaen, W., Pieters, L., Apers, S.

“…In order to investigate the potential use of Boldoa purpurascens against diabetes, the antihyperglycemic effect of an ethanol extract obtained from its leaves…”
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Alternative convergent and accelerated double-stage convergent approaches towards functionalized dendritic polyethers by Forier, B., Dehaen, W.

“…Alternative convergent synthesis strategies for the preparation of dendritic macromolecules, using either mesylate activation or the Mitsunobu reaction, are…”
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Effect of Core Structure on Photophysical and Hydrodynamic Properties of Porphyrin Dendrimers by Matos, M. S, Hofkens, J, Verheijen, W, De Schryver, F. C, Hecht, S, Pollak, K. W, Fréchet, J. M. J, Forier, B, Dehaen, W

“…The photophysical and hydrodynamic properties of dendrimers (GnPZn and GnTPPH2) with zinc porphyrin (PZn) and tetraphenylporphyrin (TPP) cores are studied in…”
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Synthesis of Dendrimers Containing 1,3,4-Oxadiazoles by Verheyde, Bert, Dehaen, Wim

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Convergent synthesis of dendrimers based on 1,3,3-trisubstituted 2-oxindoles by Vandendriessche, A., Thomas, J., Van Oosterwijck, C., Huybrechts, J., Dervaux, B., D’hollander, S., Du Prez, F., Dehaen, W., Smet, M.

“…Dendrons and dendrimers were convergently prepared using an isatin as AB 2 monomer by superelectrophilic arylation in trifluoromethanesulfonic acid. This…”
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Nucleophilic Intramolecular Cyclization Reactions of Alkynechalcogenolates by Abramov, M.A., Dehaen, W., D'hooge, B., Petrov, M.L., Smeets, S., Toppet, S., Voets, M.

“…2-( ortho-Hydroxyphenyl)-alkynethiolates and -selenolates, obtained through base catalyzed ring cleavage of 4-( ortho-hydroxyphenyl)-1,2,3-thiadiazoles and…”
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Detection of a Single Dendrimer Macromolecule with a Fluorescent Dihydropyrrolopyrroledione (DPP) Core Embedded in a Thin Polystyrene Polymer Film by Hofkens, J, Verheijen, W, Shukla, R, Dehaen, W, De Schryver, F. C

“…Three generations of dendrimers with a fluorescent core were synthesized by attaching dendrons of the Fréchet type to a dihydropyrrolopyrroledione (DPP)…”
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Flavonoids from Senecio viscosus by Suleimenov, E. M, Jose, R. A, Rakhmadieva, S. B, De Borggraeve, W, Dehaen, W

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Pharmacology of inositol trisphosphate receptors by Bultynck, G, Sienaert, I, Parys, J B, Callewaert, G, De Smedt, H, Boens, N, Dehaen, W, Missiaen, L

“…In almost all cells, cytosolic Ca(2+) is a crucial intracellular messenger, regulating many cellular processes. In non-excitable as well as in some excitable…”
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Singlet oxygen generation using PDMS occluded dyes by van Laar, F.M.P.R., Holsteyns, F., Vankelecom, I.F.J., Smeets, S., Dehaen, W., Jacobs, P.A.

“…Several dyes that generate singlet molecular oxygen (1O2) were occluded in polydimethylsiloxane (PDMS). For the homogeneous dyes, this occlusion forms an easy…”
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