Search Results - "Degryse, Amber"
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Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress
Published in The Journal of biological chemistry (02-09-2011)“…Expression of mutant surfactant protein C (SFTPC) results in endoplasmic reticulum (ER) stress in type II alveolar epithelial cells (AECs). AECs have been…”
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Journal Article -
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Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2011)“…Evidence of endoplasmic reticulum (ER) stress has been found in lungs of patients with familial and sporadic idiopathic pulmonary fibrosis. We tested whether…”
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3
Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis
Published in American journal of respiratory and critical care medicine (01-10-2009)“…Lung fibroblasts are key mediators of fibrosis resulting in accumulation of excessive interstitial collagen and extracellular matrix, but their origins are not…”
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4
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis
Published in American journal of physiology. Lung cellular and molecular physiology (01-10-2010)“…Single-dose intratracheal bleomycin has been instrumental for understanding fibrotic lung remodeling, but fails to recapitulate several features of idiopathic…”
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5
A critical role for macrophages in promotion of urethane-induced lung carcinogenesis
Published in The Journal of immunology (1950) (01-12-2011)“…Macrophages have established roles in tumor growth and metastasis, but information about their role in lung tumor promotion is limited. To assess the role of…”
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6
β-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin
Published in American journal of respiratory and critical care medicine (15-03-2013)“…Alveolar epithelial cells (AECs) play central roles in the response to lung injury and the pathogenesis of pulmonary fibrosis. We aimed to determine the role…”
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7
Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress
Published in The Journal of biological chemistry (06-02-2015)Get full text
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8
TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment
Published in American journal of physiology. Lung cellular and molecular physiology (01-06-2011)“…The response of alveolar epithelial cells (AECs) to lung injury plays a central role in the pathogenesis of pulmonary fibrosis, but the mechanisms by which…”
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Progress Toward Improving Animal Models for Idiopathic Pulmonary Fibrosis
Published in The American journal of the medical sciences (01-06-2011)“…Abstract Idiopathic pulmonary fibrosis (IPF) remains a disease with an unknown cause and a poor prognosis. Among attempts to define disease pathogenesis,…”
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Journal Article Conference Proceeding -
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Genetics in Pulmonary Fibrosis—Familial Cases Provide Clues to the Pathogenesis of Idiopathic Pulmonary Fibrosis
Published in The American journal of the medical sciences (01-06-2011)“…Abstract Idiopathic pulmonary fibrosis (IPF) is the most common form of the idiopathic interstitial pneumonias and remains a disease with a poor prognosis…”
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Journal Article Conference Proceeding -
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Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease
Published in American journal of respiratory and critical care medicine (15-02-2015)“…Asymptomatic relatives of patients with familial interstitial pneumonia (FIP), the inherited form of idiopathic interstitial pneumonia, carry increased risk…”
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12
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice
Published in Experimental lung research (01-04-2012)“…ABSTRACT Idiopathic pulmonary fibrosis (IPF) is characterized by interstitial lung infiltrates, dyspnea, and progressive respiratory failure. Reports linking…”
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13
Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice
Published in Experimental lung research (01-04-2012)“…ABSTRACT In addition to parenchymal fibrosis, fibrotic remodeling of the distal airways has been reported in interstitial lung diseases. Mechanisms of airway…”
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Journal Article -
14
PROGRESS TOWARD IMPROVING ANIMAL MODELS FOR IPF
Published in The American journal of the medical sciences (01-06-2011)“…Idiopathic pulmonary fibrosis (IPF) remains a disease with an unknown cause and a poor prognosis. Among attempts to define disease pathogenesis, animal models…”
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Journal Article -
15
GENETICS IN PULMONARY FIBROSIS – FAMILIAL CASES PROVIDE CLUES TO THE PATHOGENESIS OF IPF
Published in The American journal of the medical sciences (01-06-2011)“…Idiopathic pulmonary fibrosis (IPF) is the most common form of the idiopathic interstitial pneumonias (IIP) and remains a disease with a poor prognosis…”
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Journal Article -
16
[Beta]-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin
Published in American journal of respiratory and critical care medicine (15-03-2013)“…Alveolar epithelial cells (AECs) play central roles in the response to lung injury and the pathogenesis of pulmonary fibrosis. We aimed to determine the role…”
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Journal Article -
17
Wolf in sheep's clothing : Advanced kaposi sarcoma mimicking vulvar abscess
Published in Southern medical journal (Birmingham, Ala.) (01-04-2005)“…Kaposi sarcoma is a vascular neoplastic disorder that is associated with the acquired immunodeficiency syndrome (AIDS). The causative factor in Kaposi sarcoma…”
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Blastoschizomyces capitatus pneumonia in an immunocompetent male
Published in Southern medical journal (Birmingham, Ala.) (01-07-2004)“…Blastoschizomyces capitatus is an emerging fungal pathogen. It has been well characterized as a cause of local and disseminated disease in immunocompromised…”
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19
West Nile viruses: Clinical and diagnostic considerations
Published in Clinical microbiology newsletter (01-10-2003)“…The outbreaks in North America since 1999 have captured public attention, and West Nile viral encephalitis has been added to the designated nationally…”
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Journal Article -
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The Last Dance: Encountering Death and Dying
Published in JAMA (08-01-2003)“…"The Last Dance: Encountering Death and Dying" by Lynne Ann DeSpelder and Albert Lee Strickland is reviewed…”
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Book Review