Search Results - "Degroot, Clotilde"
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Transcranial magnetic stimulation improves cognition over time in Parkinson's disease
Published in Parkinsonism & related disorders (01-09-2019)“…Cognitive impairment can occur in the early phase of Parkinson's disease and increases the risk of developing dementia. Cognitive deficits were shown to be…”
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Aberrant neurophysiological signaling associated with speech impairments in Parkinson’s disease
Published in NPJ Parkinson's Disease (14-04-2023)“…Difficulty producing intelligible speech is a debilitating symptom of Parkinson’s disease (PD). Yet, both the robust evaluation of speech impairments and the…”
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Why Is Aging a Risk Factor for Cognitive Impairment in Parkinson's Disease?-A Resting State fMRI Study
Published in Frontiers in neurology (22-03-2019)“…Using resting-state functional MRI (rsfMRI) data of younger and older healthy volunteers and patients with Parkinson's disease (PD) with and without mild…”
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Regional brain stem atrophy in idiopathic Parkinson's disease detected by anatomical MRI
Published in PloS one (10-12-2009)“…Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder characterized by the dysfunction of dopaminergic dependent cortico-basal ganglia loops and…”
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Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease
Published in Frontiers in aging neuroscience (23-11-2016)“…Mild cognitive impairment in Parkinson's disease (PD) has been linked with functional brain changes. Previously, using functional magnetic resonance imaging…”
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Adverse and compensatory neurophysiological slowing in Parkinson’s disease
Published in Progress in neurobiology (01-12-2023)“…Patients with Parkinson’s disease (PD) exhibit multifaceted changes in neurophysiological brain activity, hypothesized to represent a global cortical slowing…”
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Mild cognitive impairment is linked with faster rate of cortical thinning in patients with Parkinson's disease longitudinally
Published in Brain (London, England : 1878) (01-04-2014)“…Previous studies have shown greater atrophy in grey and white matter of various brain regions in patients with Parkinson's disease with mild cognitive…”
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The neuro genomics partnership: A new consortium dedicated to a fully open patient to patient (P2P) integrative R&D approach
Published in Journal of the neurological sciences (01-12-2023)Get full text
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Mild cognitive impairment in patients with Parkinson's disease is associated with increased cortical degeneration
Published in Movement disorders (01-09-2013)“…ABSTRACT Mild cognitive impairment (MCI) can occur early in the course of Parkinson's disease (PD), and its presence increases the risk of developing dementia…”
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Effect of mild cognitive impairment on the patterns of neural activity in early Parkinson's disease
Published in Neurobiology of aging (2014)“…Abstract We have previously observed decreased activation of corticostriatal loops involved in planning (cognitive loop) and execution (motor loop) of a set…”
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Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience
Published in Parkinsonism & related disorders (01-10-2021)“…The COVID-19 pandemic has necessitated the social isolation of the population and the rapid implementation of remote care for patients with neurodegenerative…”
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Depressive symptoms in Parkinson’s disease correlate with cortical atrophy over time
Published in Brain and cognition (01-02-2017)“…•Early presence of depressive symptoms in PD is a marker of faster neurodegeneration.•Depressive symptoms in PD correlate with a higher neurodegeneration rate…”
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White matter degeneration profile in the cognitive cortico‐subcortical tracts in Parkinson's disease
Published in Movement disorders (01-07-2018)“…Background: In Parkinson's disease cognitive impairment is an early nonmotor feature, but it is still unclear why some patients are able to maintain their…”
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Dopamine transporter SLC6A3 genotype affects cortico-striatal activity of set-shifts in Parkinson's disease
Published in Brain (London, England : 1878) (01-11-2014)“…Parkinson's disease is a neurodegenerative condition that affects motor function along with a wide range of cognitive domains, including executive function…”
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The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository
Published in Journal of Parkinson's disease (01-01-2020)“…Genetic, biologic and clinical data suggest that Parkinson's disease (PD) is an umbrella for multiple disorders with clinical and pathological overlap, yet…”
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Advancing Parkinson’s Disease Research in Canada: The Canadian Open Parkinson Network (C-OPN) Cohort
Published in Journal of Parkinson's disease (15-10-2024)“…Background: Enhancing the interactions between study participants, clinicians, and investigators is imperative for advancing Parkinson’s disease (PD) research…”
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The C-BIG Repository: an Institution-Level Open Science Platform
Published in Neuroinformatics (Totowa, N.J.) (2022)“…In January 2016, the Montreal Neurological Institute-Hospital (The Neuro) declared itself an Open Science organization. This vision extends beyond efforts by…”
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The neurophysiological brain-fingerprint of Parkinson’s disease
Published in EBioMedicine (01-07-2024)“…Research in healthy young adults shows that characteristic patterns of brain activity define individual “brain-fingerprints” that are unique to each person…”
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Neuroimaging studies of different cognitive profiles in Parkinson's disease
Published in Parkinsonism & related disorders (2012)“…Summary It is now clear that cognitive deficits exist even early in Parkinson's disease, having a significant impact on daily activities. However, the nature…”
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