Search Results - "Degroot, Andre"
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Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
Published in Nature communications (08-10-2018)“…The ability of proteins to sense membrane curvature is essential to cellular function. All known sensing mechanisms rely on protein domains with specific…”
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2
Molecular thermodynamics of receptor competition for endocytic uptake
Published in Soft matter (25-09-2019)“…Endocytic uptake of receptors from the cell surface plays an important role in diverse processes from cell signaling to nutrient internalization. Understanding…”
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Weakly Internalized Receptors Use Coated Vesicle Heterogeneity to Evade Competition during Endocytosis
Published in Biochemistry (Easton) (13-07-2021)“…The uptake of receptors by clathrin-mediated endocytosis underlies signaling, nutrient import, and recycling of transmembrane proteins and lipids. In the…”
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Entropic Control of Receptor Recycling Using Engineered Ligands
Published in Biophysical journal (27-03-2018)“…Receptor internalization by endocytosis regulates diverse cellular processes, from the rate of nutrient uptake to the timescale of essential signaling events…”
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Receptor Heterodimerization Modulates Endocytosis through Collaborative and Competitive Mechanisms
Published in Biophysical journal (20-08-2019)“…Recruitment of receptors into clathrin-coated structures is essential to signal transduction and nutrient uptake. Among the many receptors involved in these…”
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6
Low Affinity Receptors Can Enter Endocytic Pits by Binding to High Affinity Receptors
Published in Biophysical journal (02-02-2018)Get full text
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Receptors Utilize Coated Vesicle Heterogeneity to Evade Competition during Endocytosis
Published in Biophysical journal (07-02-2020)Get full text
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8
CD4-Targeted Fusosomes Are Capable of Transducing Resting T Helper Cells to Generate Highly Potent CAR-T Cells
Published in Blood (23-11-2021)“…Introduction: Chimeric antigen receptor T cell therapy (CAR T) is a successful treatment for B cell malignancies; however, the time, complexity and cost of…”
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Bulky Ligands as Entropic Inhibitors of Receptor Uptake by Endocytosis
Published in Biophysical journal (03-02-2017)Get full text
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Biophysical Control of Receptor Recycling Using Engineered Ligands
Published in Biophysical journal (02-02-2018)Get full text
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Intrinsically Disordered Proteins Sense Membrane Curvature
Published in Biophysical journal (01-02-2019)Get full text
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Abstract 16315: Transmembrane Stem Cell Factor Nanodiscs Enhance Revascularization in Ischemia and Have Less Mast Cell Activation
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionThe invasiveness of standard treatments for peripheral vascular disease (PVD) precludes their use in some patients and often does not provide a…”
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