Search Results - "Degraeuwe, Pieter L"
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The bioavailability and maturing clearance of doxapram in preterm infants
Published in Pediatric research (01-04-2021)“…Background Doxapram is used for the treatment of apnea of prematurity in dosing regimens only based on bodyweight, as pharmacokinetic data are limited. This…”
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Intrauterine Growth Restriction and Patent Ductus Arteriosus in Very and Extremely Preterm Infants: A Systematic Review and Meta-Analysis
Published in Frontiers in endocrinology (Lausanne) (08-02-2019)“…It is generally accepted that intrauterine growth restriction (IUGR) increases morbidity and mortality among very preterm neonates. However, evidence is…”
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A failed attempt to conduct an individual patient data meta-analysis
Published in Systematic reviews (04-09-2014)“…A study-level meta-analysis has shown that proton magnetic resonance spectroscopy is a promising prognostic marker in neonatal hypoxic-ischemic encephalopathy…”
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Pleural effusion due to intra‐abdominal extravasation of parenteral nutrition
Published in Pediatric pulmonology (01-10-2008)“…An 8‐week‐old preterm boy experienced respiratory deterioration due to unilateral pleural effusion. Intra‐abdominal extravasation of parenteral fluid with…”
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Chorioamnionitis appears not to be a Risk Factor for Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis
Published in Scientific reports (28-11-2016)“…The contribution of chorioamnionitis (CA) to mortality and morbidity in preterm infants is difficult to assess because observational studies frequently present…”
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Non-Invasive Markers for Early Diagnosis and Determination of the Severity of Necrotizing Enterocolitis
Published in Annals of surgery (01-06-2010)“…To improve diagnosis of necrotizing enterocolitis (NEC) by noninvasive markers representing gut wall integrity loss (I-FABP and claudin-3) and gut wall…”
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Model-based clinical dose optimization for phenobarbital in neonates: An illustration of the importance of data sharing and external validation
Published in European journal of pharmaceutical sciences (15-11-2017)“…Particularly in the pediatric clinical pharmacology field, data-sharing offers the possibility of making the most of all available data. In this study, we…”
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Protein binding of flucloxacillin in neonates
Published in Therapeutic drug monitoring (01-06-2007)“…The isoxazolyl penicillins, including flucloxacillin, have the highest levels of plasma protein binding among the semisynthetic penicillins. Because only the…”
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Enantiomer specific pharmacokinetics of ibuprofen in preterm neonates with patent ductus arteriosus
Published in British journal of clinical pharmacology (01-10-2020)“…Aims Racemic ibuprofen is widely used for the treatment of preterm neonates with patent ductus arteriosus. Currently used bodyweight‐based dosing guidelines…”
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Population pharmacokinetics and dosing of flucloxacillin in preterm and term neonates
Published in Therapeutic drug monitoring (01-06-2006)“…In total 235 flucloxacillin total (free+protein bound) plasma concentrations were determined in 55 neonates (gestational age 26 to 42 weeks, postnatal age 0 to…”
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Faecal Calprotectin in Suspected Paediatric Inflammatory Bowel Disease
Published in Journal of pediatric gastroenterology and nutrition (01-03-2015)“…ABSTRACT Objectives: The diagnostic accuracy of faecal calprotectin (FC) concentration for paediatric inflammatory bowel disease (IBD) is well described at the…”
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Pharmacokinetics of intravenous rifampicin (ifampin) in neonates
Published in Therapeutic drug monitoring (01-10-2006)“…Few reports have addressed neonatal rifampicin plasma concentrations and data on neonatal rifampicin pharmacokinetics are completely lacking. Therefore, plasma…”
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Rapid Feeding Volume Advancements: Uncertainty About the Effect on Necrotizing Enterocolitis Incidence
Published in Pediatrics (Evanston) (01-05-2005)Get full text
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Letter by Degraeuwe and Been regarding article, "Evidence of arteriolar narrowing in low-birth-weight children"
Published in Circulation (New York, N.Y.) (26-05-2009)Get full text
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The removal-associated sepsis prevention trial in preterm newborns was ended in an untimely manner
Published in Pediatric critical care medicine (01-03-2012)Get full text
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The diagnostic value of inter-alpha inhibitor proteins for neonatal sepsis
Published in The Journal of pediatrics (01-02-2010)Get full text
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Drug dosing in pediatric intensive care and in pediatrics in general
Published in Pediatric critical care medicine (01-07-2011)Get full text
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Population pharmacokinetics and dosing of amoxicillin in (Pre)term neonates
Published in Therapeutic drug monitoring (01-04-2006)“…Amoxicillin plasma concentrations, pharmacokinetic parameters, and the influence of demographic, anthropometric, and clinical covariates were investigated in…”
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Why partial liquid ventilation did not fulfill its promise
Published in American journal of respiratory and critical care medicine (01-09-2006)Get full text
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