Search Results - "Degen, W G"

Vaccine Immunopotentiators of the Future by Schijns, V E J C, Degen, W G J

“…Vaccine adjuvants or immunopotentiators comprise a diverse group of molecules or formulations. Despite a wealth of different candidates, there is a need for…”
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MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule) by Degen, WG, van Kempen, LC, Gijzen, EG, van Groningen, JJ, van Kooyk, Y, Bloemers, HP, Swart, GW

“…From a differential mRNA display comparing a non- and a highly metastasizing human melanoma cell line, we isolated and characterized memD. memD is…”
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nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts by Weterman, M A, Ajubi, N, van Dinter, I M, Degen, W G, van Muijen, G N, Ruitter, D J, Bloemers, H P

“…From a subtractive cDNA library, we isolated several cDNA clones which showed differential expression between highly and lowly metastatic human melanoma cell…”
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Caspase-dependent cleavage of nucleic acids by Degen, W G, Pruijn, G J, Raats, J M, van Venrooij, W J

“…Autoimmune diseases are frequently characterized by the presence of autoantibodies directed against nucleic acid-protein complexes present in the nucleus of…”
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The fate of U1 snRNP during anti-Fas induced apoptosis: specific cleavage of the U1 snRNA molecule by Degen, W G, Aarssen, Y, Pruijn, G J, Utz, P J, van Venrooij, W J

“…During apoptosis, the U1-70K protein, a component of the spliceosomal U1 snRNP complex, is specifically cleaved by the enzyme caspase-3, converting it into a…”
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Expression of nma, a novel gene, inversely correlates with the metastatic potential of human melanoma cell lines and xenografts by Degen, Winfried G. J., Weterman, Marian A. J., van Groningen, Jan J. M., Cornelissen, Ine M. A. H., Lemmers, Jolanda P. W. M., Agterbos, Marloes A., van Kessel, Ad Geurts, Swart, Guido W. M., Bloemers, Henri P. J.

“…nma, a novel gene, was isolated by using a subtractive hybridization technique in which the gene expression was compared in a panel of human melanoma cell…”
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Molecular Basis for the Homophilic Activated Leukocyte Cell Adhesion Molecule (ALCAM)-ALCAM Interaction by van Kempen, Léon C.L.T., Nelissen, Judith M.D.T., Degen, Winfried G.J., Torensma, Ruurd, Weidle, Ulrich H., Bloemers, Henri P.J., Figdor, Carl G., Swart, Guido W.M.

“…Activated leukocyte cell adhesion molecule (ALCAM/CD166), a member of the immunoglobulin superfamily with five extracellular immunoglobulin-like domains,…”
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Response to "'Post-alum Adjuvants' May Reach Beyond Their Intended Purpose: The Clinical Development of TLR Agonists" by Schijns, VEJC, Degen, WGJ

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Characterization of recombinant human autoantibody fragments directed toward the autoantigenic U1‐70K protein by Degen, Winfried G. J., Pieffers, Martijn, Welin‐Henriksson, Elisabet, van den Hoogen, Frank H. J., van Venrooij, Walther J., Raats, Jos M. H.

“…The U1‐70K protein is specifically bound to stemloop I of the U1 small nuclear RNA contained in the U1 small nuclear ribonucleoprotein complex (U1 snRNP),…”
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memA/DRS, a putative mediator of multiprotein complexes, is overexpressed in the metastasizing human melanoma cell lines BLM and MV3 by Degen, W G, Agterbos, M A, Muyrers, J P, Bloemers, H P, Swart, G W

“…memA was isolated by subtractive hybridization in which the mRNA repertoire was compared in a panel of human melanoma cell lines with different metastasizing…”
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