Search Results - "Defreyte, Gilberto"
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The effects of complete versus incomplete mitral valve repair in experimental mitral regurgitation
Published in The Journal of thoracic and cardiovascular surgery (01-02-1994)“…Severe mitral regurgitation (regurgitant fraction 0.75 +/- 0.02) was created in eight dogs by our closed-chest chordal rupture technique. After 3 months of…”
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Journal Article -
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Effects of Gene Deletion of the Tissue Inhibitor of the Matrix Metalloproteinase-type 1 (TIMP-1) on Left Ventricular Geometry and Function in Mice
Published in Journal of molecular and cellular cardiology (01-01-2000)“…L. Roten, S. Nemoto, J. Simsic, M. L. Coker, V. Rao, S. Baicu, G. Defreyte, P. J. Soloway, M. R. Zile and F. G. Spinale. Effects of Gene Deletion of the Tissue…”
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3
Microtubule depolymerization normalizes in vivo myocardial contractile function in dogs with pressure-overload left ventricular hypertrophy
Published in Circulation (New York, N.Y.) (29-08-2000)“…BACKGROUND: Because initially compensatory myocardial hypertrophy in response to pressure overloading may eventually decompensate to myocardial failure,…”
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Journal Article -
4
Effects of chronic beta-adrenergic blockade on the left ventricular and cardiocyte abnormalities of chronic canine mitral regurgitation
Published in The Journal of clinical investigation (01-06-1994)“…The mechanism by which beta blockade improves left ventricular dysfunction in various cardiomyopathies has been ascribed to improved contractile function of…”
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Journal Article -
5
Premorbid determinants of left ventricular dysfunction in a novel model of gradually induced pressure overload in the adult canine
Published in Circulation (New York, N.Y.) (18-03-1997)“…BACKGROUND: When a pressure overload is placed on the left ventricle, some patients develop relatively modest hypertrophy whereas others develop extensive…”
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Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation
Published in The American journal of physiology (01-02-1999)“…Myocardial hypertrophy is one of the basic mechanisms by which the heart compensates for hemodynamic overload. The mechanisms by which hemodynamic overload is…”
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Journal Article -
7
Pressure-overload hypertrophy is unabated in mice devoid of AT1A receptors
Published in The American journal of physiology (01-03-1998)“…Mechanisms controlling cardiac growth are under intense investigation. Among these, the renin-angiotensin system has received great interest. In the current…”
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Journal Article -
8
Native β-adrenergic support for left ventricular dysfunction in experimental mitral regurgitation normalizes indexes of pump and contractile function
Published in Circulation (New York, N.Y.) (01-02-1994)“…It is generally accepted that the adrenergic nervous system provides inotropic support for the failing heart. However, the magnitude of this support has never…”
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Conference Proceeding Journal Article -
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Left ventricular mechanics and myocyte function after correction of experimental chronic mitral regurgitation by combined mitral valve replacement and preservation of the native mitral valve apparatus
Published in Circulation (New York, N.Y.) (01-11-1992)“…Contractile function improves after correction of experimental mitral regurgitation, but ejection performance becomes depressed when mitral valve replacement…”
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Journal Article -
10
Coronary Blood Flow After the Regression of Pressure-Overload Left Ventricular Hypertrophy
Published in Circulation research (01-12-1992)“…Abnormal coronary blood flow (CBF) in long-standing left ventricular (LV) pressure-overload hypertrophy has been associated with ischemia and LV dysfunction…”
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Journal Article -
11
An Adult Canine Model of Progressive Left Ventricular Pressure Overload
Published in Journal of investigative surgery (1997)“…This article details the development of a model of progressive left ventricular pressure overload (LVPO) in the adult dog. LVPO was induced by banding the…”
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Journal Article