Search Results - "Defres, Sylviane"

Clinical predictors of encephalitis in UK adults–A multi-centre prospective observational cohort study by Defres, Sylviane, Tharmaratnam, Kukatharmini, Michael, Benedict D, Ellul, Mark, Davies, Nicholas W. S, Easton, Ava, Griffiths, Michael J, Bhojak, Maneesh, Das, Kumar, Hardwick, Hayley, Cheyne, Chris, Kneen, Rachel, Medina-Lara, Antonieta, Salter, Anne Christine, Beeching, Nicholas J, Carrol, Enitan, Vincent, Angela, Garcia-Finana, Marta, Solomon, Tom

“…Objectives Encephalitis, brain inflammation and swelling, most often caused by an infection or the body’s immune defences, can have devastating consequences,…”
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Understanding parental perspectives on outcomes following paediatric encephalitis: A qualitative study by Lemon, Jennifer, Cooper, Jessie, Defres, Sylviane, Easton, Ava, Sadarangani, Manish, Griffiths, Michael J, Pollard, Andrew J, Solomon, Tom, Kneen, Rachel

“…Encephalitis, characterised as inflammation of the brain tissue, is an important cause of acquired brain injury in children. Objective clinical outcomes vary…”
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Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis by Cooper, Jessie, Kierans, Ciara, Defres, Sylviane, Easton, Ava, Kneen, Rachel, Solomon, Tom

“…Herpes simplex virus (HSV) encephalitis is a potentially devastating disease, with significant rates of mortality and co-morbidities. Although the prognosis…”
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Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis by Cooper, Jessie, Kierans, Ciara, Defres, Sylviane, Easton, Ava, Kneen, Rachel, Solomon, Tom

“…Herpes simplex virus (HSV) encephalitis is a life-threatening infection of the brain, which has significant physical, cognitive and social consequences for…”
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Protocol for DexEnceph: a randomised controlled trial of dexamethasone therapy in adults with herpes simplex virus encephalitis by Whitfield, Thomas, Fernandez, Cristina, Davies, Kelly, Defres, Sylviane, Griffiths, Michael, Hooper, Cory, Tangney, Rebecca, Burnside, Girvan, Rosala- Hallas, Anna, Moore, Perry, Das, Kumar, Zuckerman, Mark, Parkes, Laura, Keller, Simon, Roberts, Neil, Easton, Ava, Touati, Saber, Kneen, Rachel, Stahl, J P, Solomon, Tom

“…IntroductionHerpes simplex virus (HSV) encephalitis is a rare severe form of brain inflammation that commonly leaves survivors and their families with…”
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A pragmatic cluster randomised controlled trial of a tailored intervention to improve the initial management of suspected encephalitis by Backman, Ruth, Foy, Robbie, Diggle, Peter J, Kneen, Rachel, Easton, Ava, Defres, Sylviane, McGill, Fiona, Michael, Benedict Daniel, Solomon, Tom

“…To determine whether a tailored multifaceted implementation strategy improves the initial management of patients with suspected encephalitis. Pragmatic two arm…”
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Correction: Increased volume of cerebral oedema is associated with risk of acute seizure activity and adverse neurological outcomes in encephalitis – regional and volumetric analysis in a multi-centre cohort by Alam, Ali M, Chen, Jian P. K, Wood, Greta K, Facer, Bethany, Bhojak, Maneesh, Das, Kumar, Defres, Sylviane, Marson, Anthony, Granerod, Julia, Brown, David, Thomas, Rhys H, Keller, Simon S, Solomon, Tom, Michael, Benedict D

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A Feasibility Study of Quantifying Longitudinal Brain Changes in Herpes Simplex Virus (HSV) Encephalitis Using Magnetic Resonance Imaging (MRI) and Stereology by Defres, Sylviane, Keller, Simon S, Das, Kumar, Vidyasagar, Rishma, Parkes, Laura M, Burnside, Girvan, Griffiths, Michael, Kopelman, Michael, Roberts, Neil, Solomon, Tom

“…To assess whether it is feasible to quantify acute change in temporal lobe volume and total oedema volumes in herpes simplex virus (HSV) encephalitis as a…”
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Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts by Wood, Greta K, Babar, Roshan, Ellul, Mark A, Thomas, Rhys Huw, Van Den Tooren, Harriet, Easton, Ava, Tharmaratnam, Kukatharmini, Burnside, Girvan, Alam, Ali M, Castell, Hannah, Boardman, Sarah, Collie, Ceryce, Facer, Bethany, Dunai, Cordelia, Defres, Sylviane, Granerod, Julia, Brown, David W G, Vincent, Angela, Marson, Anthony Guy, Irani, Sarosh R, Solomon, Tom, Michael, Benedict D

“…ObjectiveIn patients with encephalitis, the development of acute symptomatic seizures is highly variable, but when present is associated with a worse outcome…”
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A patient satisfaction survey and educational package to improve the care of people hospitalised with COVID-19: a quality improvement project, Liverpool, UK by Ahmad, Muhammad Shamsher, Hicks, Scott Rory, Watson, Rebecca, Ahmed, Rajia Akter, Jones, Lewis, Vaselli, Marcella, Wu, Meng-San, Hayat, Fatima, Ratcliffe, Libuse, McKenna, Mark, Hine, Paul, Defres, Sylviane, Wingfield, Tom

“…The perspectives and experiences of people hospitalised with COVID-19 have been under-reported during the coronavirus pandemic. We developed and conducted a…”
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A patient satisfaction survey and educational package to improve the care of people hospitalised with COVID-19: a quality improvement project, Liverpool, UK by Ahmad, Muhammad Shamsher, Hicks, Scott Rory, Watson, Rebecca, Ahmed, Rajia Akter, Jones, Lewis, Vaselli, Marcella, Wu, Meng-San, Hayat, Fatima, Ratcliffe, Libuse, McKenna, Mark, Hine, Paul, Defres, Sylviane, Wingfield, Tom

“…Background: The perspectives and experiences of people hospitalised with COVID-19 have been under-reported during the coronavirus pandemic. We developed and…”
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Neurological associations of COVID-19 by Ellul, Mark A, Benjamin, Laura, Singh, Bhagteshwar, Lant, Suzannah, Michael, Benedict Daniel, Easton, Ava, Kneen, Rachel, Defres, Sylviane, Sejvar, Jim, Solomon, Tom

“…The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is of a scale not seen since the 1918 influenza pandemic…”
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Characterising the molecular epidemiology of human parechovirus in young infants in the UK and Canada by Kadambari, Seilesh, Harvala, Heli, Nguyen, Dung, Sadarangani, Manish, Martin, Natalie G, Al-Rawahi, Ghada N., Sekirov, Inna, Defres, Sylviane, Solomon, Tom, Golubchik, Tanya, Bowden, Rory, Pollard, Andrew J, Simmonds, Peter

“…•Most human parechovirus (HPeV) infections detected in infants were genotype 3 (HPeV-A3; 57/58 cases).•A genotype 5 strain (HPeV-A5) was detected for the first…”
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‘More than devastating’—patient experiences and neurological sequelae of Japanese encephalitis by Turtle, Lance, Easton, Ava, Defres, Sylviane, Ellul, Mark, Bovill, Begona, Hoyle, Jim, Jung, Agam, Lewthwaite, Penny, Solomon, Tom

“…Abstract Background Japanese encephalitis (JE), caused by the mosquito-borne JE virus, is a vaccine-preventable disease endemic to much of Asia. Travellers…”
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Evaluating the Impact of the BioFire FilmArray in Childhood Meningitis: An Observational Cohort Study by Kadambari, Seilesh, Feng, Shuo, Liu, Xinxue, Andersson, Monique, Waterfield, Rebecca, Fodder, Harriet, Jacquemot, Aimee, Galal, Ushma, Rafferty, Aisling, Drew, Richard J, Rodrigues, Charlene, Sadarangani, Manish, Riordan, Andrew, Martin, Natalie G, Defres, Sylviane, Solomon, Tom, Pollard, Andrew J, Paulus, Stephane

“…Multiplex polymerase chain reaction assays have the potential to reduce antibiotic use and shorten length of inpatient stay in children with suspected central…”
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Acute seizure risk in encephalitis; analysis and modelling of 436 patients from two independent multi-centre cohorts (S38.008) by Wood, Greta, Ellul, Mark, Thomas, Rhys, Easton, Ava, Burnside, Girvan, Dunai, Cordelia, Alam, Ali, Boardman, Sarah, Collie, Ceryce, Castell, Hannah, Facer, Bethany, Defres, Sylviane, Granerod, Julia, Brown, David, Vincent, Angela, Solomon, Tom, Michael, Benedict

“…Abstract only…”
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UK guidelines for the investigation and management of eosinophilia in returning travellers and migrants by Thakker, Clare, Warrell, Clare, Barrett, Jessica, Booth, Helen L, Chiodini, Peter L, Defres, Sylviane, Falconer, Jane, Jacobs, Nathan, Jones, Jayne, Lambert, Jonathan, Leong, Clare, McBride, Angela, Moore, Elinor, Moshiri, Tara, Nabarro, Laura E, O’Hara, Geraldine, Stone, Neil, van Halsema, Clare, Checkley, Anna M

“…Eosinophilia is a common finding in returning travellers, migrants and other travelling groups. In this setting it often indicates an underlying helminth…”
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What do people hospitalised with covid-19 think about the care they received? by Wu, Meng-San, Hayat, Fatima, Ratcliffe, Libuse, Beadsworth, Mike B J, Defres, Sylviane, Wingfield, Tom

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Post-hospitalisation COVID-19 cognitive deficits at one year are global and associated with elevated brain injury markers and grey matter volume reduction by Wood, Greta K, Sargent, Brendan F, Ahmad, Zain-Ul-Abideen, Tharmaratnam, Kukatharmini, Dunai, Cordelia, Egbe, Franklyn N, Martin, Naomi H, Facer, Bethany, Pendered, Sophie L, Rogers, Henry C, Hübel, Christopher, van Wamelen, Daniel J, Bethlehem, Richard A I, Giunchiglia, Valentina, Hellyer, Peter J, Trender, William, Kalsi, Gursharan, Needham, Edward, Easton, Ava, Jackson, Thomas A, Cunningham, Colm, Upthegrove, Rachel, Pollak, Thomas A, Hotopf, Matthew, Solomon, Tom, Pett, Sarah L, Shaw, Pamela J, Wood, Nicholas, Harrison, Neil A, Miller, Karla L, Jezzard, Peter, Williams, Guy, Duff, Eugene P, Williams, Steven, Zelaya, Fernando, Smith, Stephen M, Keller, Simon, Broome, Matthew, Kingston, Nathalie, Husain, Masud, Vincent, Angela, Bradley, John, Chinnery, Patrick, Menon, David K, Aggleton, John P, Nicholson, Timothy R, Taylor, John-Paul, David, Anthony S, Carson, Alan, Bullmore, Ed, Breen, Gerome, Hampshire, Adam, Michael, Benedict D, Paddick, Stella-Maria, Leek, E Charles

“…The spectrum, pathophysiology, and recovery trajectory of persistent post-COVID-19 cognitive deficits are unknown, limiting our ability to develop prevention…”
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The development of an intervention to promote adherence to national guidelines for suspected viral encephalitis by Backman, Ruth, Foy, Robbie, Michael, Benedict Daniel, Defres, Sylviane, Kneen, Rachel, Solomon, Tom

“…Central nervous system infections can have devastating clinical outcomes if not diagnosed and treated promptly. There is a documented gap between recommended…”
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