Search Results - "Defrêne, Joan"
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Deletion of S100a8 and S100a9 Enhances Skin Hyperplasia and Promotes the Th17 Response in Imiquimod-Induced Psoriasis
Published in The Journal of immunology (1950) (01-02-2021)“…High concentrations of the damage-associated molecular patterns S100A8 and S100A9 are found in skin and serum from patients suffering from psoriasis, an…”
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Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Tumor hypoxia and aerobic glycolysis are well-known resistance factors for anticancer therapies. Here, we demonstrate that tumor-associated macrophages (TAM)…”
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Enhanced myelopoiesis and aggravated arthritis in S100a8-deficient mice
Published in PloS one (22-08-2019)“…Expressed strongly by myeloid cells, damage-associated molecular pattern (DAMP) proteins S100A8 and S100A9 are found in the serum of patients with infectious…”
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Innate and adaptive immune responses toward nanomedicines
Published in Acta pharmaceutica Sinica. B (01-04-2021)“…Since the commercialization of the first liposomes used for drug delivery, Doxil/Caelyx® and Myocet®, tremendous progress has been made in understanding…”
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Regulation of TLR3 Activation by S100A9
Published in The Journal of immunology (1950) (01-11-2015)“…Recognition of viral dsRNA by endosomal TLR3 activates innate immune response during virus infection. Trafficking of TLR3 to the endolysosomal compartment…”
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Role of the complement cascade in the biological fate of liposomes in rodents
Published in Nanoscale (28-09-2020)“…Nanomedicines, including liposomes, have been used to improve the clinical efficacy and safety of drugs. In some liposomal formulations, a hydrophilic polymer…”
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Regulation of toll-like receptor 3 activation by S100A9
Published in The Journal of immunology (1950) (18-09-2015)“…Recognition of viral dsRNA by endosomal toll-like receptor 3 (TLR3) activates innate immune response during virus infection. Trafficking of TLR3 to the…”
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Deciphering the Role of RAS Pathway Mutations in the Biology of Human Acute Myeloid Leukemia Using In Vivo Models
Published in Blood (02-11-2023)“…Acute myeloid leukemia (AML) is a genetically heterogeneous hematologic malignancy for which the mutational profile of the leukemic cells is the most important…”
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