Search Results - "Deffieu, Maïka S"
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LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4 + T lymphocytes
Published in Autophagy (02-08-2024)“…HIV-1 entry into CD4 T lymphocytes relies on the viral and cellular membranes' fusion, leading to viral capsid delivery in the target cell cytoplasm. Atg8/LC3B…”
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Niemann–Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2011)“…Niemann–Pick type C1 (NPC1) protein is needed for cellular utilization of low-density lipoprotein-derived cholesterol that has been delivered to lysosomes. The…”
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Post-lockdown detection of SARS-CoV-2 RNA in the wastewater of Montpellier, France
Published in One health (01-12-2020)“…The evolution of the COVID-19 pandemic can be monitored through the detection of SARS-CoV-2 RNA in sewage. Here, we measured the amount of SARS-CoV-2 RNA at…”
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-2015)“…Lysosomes are lined with a glycocalyx that protects the limiting membrane from the action of degradative enzymes. We tested the hypothesis that Niemann-Pick…”
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The Toxoplasma gondii dense granule protein TgGRA3 interacts with host Golgi and dysregulates anterograde transport
Published in Biology open (2019)“…After entry into the host cell, the intracellular parasite resides within a membrane-bound compartment, the parasitophorous vacuole (PV). The PV defines an…”
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Special issue for biology of the cell “intracellular trafficking of viruses”
Published in Biology of the cell (01-08-2023)Get full text
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Imaging the Hepatitis B Virus: Broadcasting Live
Published in Trends in microbiology (Regular ed.) (01-10-2019)“…Although important breakthroughs in our understanding of the hepatitis B virus (HBV) life cycle have been made since the discovery of its main entry factor,…”
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TMED10 mediates the loading of neosynthesised Sonic Hedgehog in COPII vesicles for efficient secretion and signalling
Published in Cellular and molecular life sciences : CMLS (01-09-2023)“…The morphogen Sonic Hedgehog (SHH) plays an important role in coordinating embryonic development. Short- and long-range SHH signalling occurs through a variety…”
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Ebola virus entry requires the host-programmed recognition of an intracellular receptor
Published in The EMBO journal (18-04-2012)“…Ebola and Marburg filoviruses cause deadly outbreaks of haemorrhagic fever. Despite considerable efforts, no essential cellular receptors for filovirus entry…”
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Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization
Published in Hepatology (Baltimore, Md.) (01-10-2022)“…Background and Aims Numerous HCV entry factors have been identified, and yet information regarding their spatiotemporal dynamics is still limited…”
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Characterisation of endogenous Claudin‐1 expression, motility and susceptibility to hepatitis C virus in CRISPR knock‐in cells
Published in Biology of the cell (01-05-2020)“…Background Information Claudin‐1 (CLDN1) is a four‐span transmembrane protein localised at cell–cell tight junctions (TJs), playing an important role in…”
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Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis
Published in Nature microbiology (01-05-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with short- and long-term neurological complications. The variety of…”
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Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway
Published in Science advances (08-01-2021)“…The biosynthetic secretory pathway is particularly challenging to investigate as it is underrepresented compared to the abundance of the other intracellular…”
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First person – Maika S. Deffieu
Published in Biology open (15-03-2019)“…First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote…”
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Characterization of endogenous Claudin1 expression, motility and susceptibility to Hepatitis C Virus in CRISPR knock-in cells
Published in Biology of the cell (20-02-2020)Get full text
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LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes
Published in Autophagy (02-08-2024)“…HIV-1 entry into CD4 + T lymphocytes relies on the viral and cellular membranes' fusion, leading to viral capsid delivery in the target cell cytoplasm…”
Get full text
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Ebola virus entry requires the host-programmed recognition of an intracellular receptor: Niemann-Pick C1 is a critical filovirus receptor
Published in The EMBO journal (18-04-2012)Get full text
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