Search Results - "Dees, W. Les"
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Insulin-Like Growth Factor-I Activates KiSS-1 Gene Expression in the Brain of the Prepubertal Female Rat
Published in Endocrinology (Philadelphia) (01-01-2009)“…KiSS-1 gene expression has been shown to increase as puberty approaches, and its peptide products, kisspeptins, are involved in LHRH secretion at puberty…”
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2
Host neuro- immuno-endocrine responses in periodontal disease
Published in Current pharmaceutical design (01-01-2014)“…Periodontitis is a chronic inflammatory complex disease caused by microorganisms. It may be influenced by diverse systemic disorders, environmental, genetic…”
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Insulin-like growth factor-1 stimulation of hypothalamic KiSS-1 gene expression is mediated by Akt: effect of alcohol
Published in Neuroscience (17-03-2010)“…Abstract Kisspeptin, as well as insulin-like growth factor-1 (IGF-1), act centrally to stimulate luteinizing hormone-releasing hormone (LHRH) secretion at…”
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Short-Term Alcohol Administration Alters KiSS-1 Gene Expression in the Reproductive Hypothalamus of Prepubertal Female Rats
Published in Alcoholism, clinical and experimental research (01-09-2009)“…Background: Kisspeptins bind to the G‐protein‐coupled receptor (GPR54) to activate hypothalamic luteinizing hormone releasing hormone (LHRH) secretion at the…”
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Manganese Acts Centrally to Stimulate Luteinizing Hormone Secretion: A Potential Influence on Female Pubertal Development
Published in Toxicological sciences (01-06-2005)“…Manganese (Mn), an essential element considered important for normal growth and reproduction, has been shown in adults to be detrimental to reproductive…”
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Actions and Interactions of Alcohol and Insulin-Like Growth Factor-1 on Female Pubertal Development
Published in Alcoholism, clinical and experimental research (01-11-2009)“…Alcohol (ALC) is a drug that is capable of disrupting reproductive function in adolescent humans, as well as immature rhesus monkeys and rats. Critical to…”
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Cilostazol blocks pregnancy in naturally cycling mice
Published in Contraception (Stoneham) (01-04-2013)“…Abstract Background Administration of a phosphodiesterase three enzyme inhibitor (PDE3-I) in rodents and primates results in ovulation of immature oocytes…”
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Manganese acts centrally to activate reproductive hormone secretion and pubertal development in male rats
Published in Reproductive toxicology (Elmsford, N.Y.) (01-11-2006)“…Manganese (Mn) is an important element for normal growth and reproduction. Because Mn accumulates in the hypothalamus and is capable of stimulating…”
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Origin and Ontogeny of Mammalian Ovarian Neurons
Published in Endocrinology (Philadelphia) (01-08-2006)“…Mammalian ovaries contain sympathetic neurons expressing the low affinity neurotropin receptor (p75NTR). To date neither the role these neurons might play in…”
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Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action
Published in The Journal of physiology (01-02-2007)“…We have shown recently that Mn 2+ stimulates gonadotropin secretion via an action at the hypothalamic level, and a diet supplemented with a low dose of the…”
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Hypothalamic glial-to-neuronal signaling during puberty: influence of alcohol
Published in International journal of environmental research and public health (01-07-2011)“…Mammalian puberty requires complex interactions between glial and neuronal regulatory systems within the hypothalamus that results in the timely increase in…”
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Alcohol Alters Luteinizing Hormone Secretion in Immature Female Rhesus Monkeys by a Hypothalamic Action
Published in Endocrinology (Philadelphia) (01-10-2004)“…We determined whether the effect of alcohol (ALC) to suppress LH secretion in immature female monkeys is due to a hypothalamic or pituitary site of action…”
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Effects of alcohol on intraovarian nitric oxide synthase and steroidogenic acute regulatory protein in the prepubertal female rhesus monkey
Published in Journal of Studies on Alcohol and Drugs (01-03-2007)“…In addition to affecting hypothalamic-pituitary function, alcohol is a gonadal toxin capable of inhibiting ovarian function and suppressing circulating levels…”
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Influence of estradiol on insulin-like growth factor-1-induced luteinizing hormone secretion
Published in Brain research (02-07-2004)“…Several studies suggest an interrelationship between estradiol (E 2) and insulin-like growth factor-1 (IGF-1) at the hypothalamic level. The present study was…”
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Intrinsic neurons in the mammalian ovary
Published in Microscopy research and technique (15-12-2002)“…Mammalian ovarian function is under endocrine and neural control. Although the extrinsic innervation of the ovary has been implicated in the control of both…”
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The Alcohol-Induced Suppression of Ovarian Insulin-Like Growth Factor-1 Gene Transcription Is Independent of Growth Hormone and Its Receptor
Published in Alcoholism, clinical and experimental research (01-05-2007)“…Background: Insulin‐like growth factor‐1 (IGF‐1) plays an important role in ovarian development and function. Alcohol (ALC) is a gonadal toxin and capable of…”
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Alcohol Suppresses Insulin-Like Growth Factor-1 Gene Expression in Prepubertal Transgenic Female Mice Overexpressing the Bovine Growth Hormone Gene
Published in Alcoholism, clinical and experimental research (01-11-2002)“…Background Alcohol (ALC) delays puberty in female rats and alters the development of a normal menstrual pattern in rhesus monkeys. These actions are associated…”
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Lipopolysaccharide-induced leptin synthesis and release are differentially controlled by alpha-melanocyte-stimulating hormone
Published in Neuroimmunomodulation (01-01-2005)“…Since alpha-melanocyte-stimulating hormone (alpha-MSH) inhibits the synthesis and release of proinflammatory cytokines and stimulates the synthesis and release…”
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Effect of ethanol on follicle stimulating hormone-induced steroidogenic acute regulatory protein (StAR) in cultured rat granulosa cells
Published in Alcohol (Fayetteville, N.Y.) (01-10-2005)“…Steroidogenic acute regulatory protein (StAR) plays a critical role in trophic hormone-stimulated steroid biosynthesis by facilitating the transfer of…”
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The Pyrethroid Pesticide Esfenvalerate Suppresses the Afternoon Rise of Luteinizing Hormone and Delays Puberty in Female Rats
Published in Environmental health perspectives (01-09-2008)“…Background: One of the most widely used classes of insecticides is the synthetic pyrethroids. Although pyrethroids are less acutely toxic to humans than to…”
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