Search Results - "Deering, Raquel"

Fulminant Myocarditis with Combination Immune Checkpoint Blockade by Johnson, Douglas B, Balko, Justin M, Compton, Margaret L, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R, Bloomer, Tyler L, Becker, Jason R, Slosky, David A, Phillips, Elizabeth J, Pilkinton, Mark A, Craig-Owens, Laura, Kola, Nina, Plautz, Gregory, Reshef, Daniel S, Deutsch, Jonathan S, Deering, Raquel P, Olenchock, Benjamin A, Lichtman, Andrew H, Roden, Dan M, Seidman, Christine E, Koralnik, Igor J, Seidman, Jonathan G, Hoffman, Robert D, Taube, Janis M, Diaz, Luis A, Anders, Robert A, Sosman, Jeffrey A, Moslehi, Javid J

“…Fatal autoimmune myocarditis with rhabdomyolysis and refractory arrhythmias developed in two patients treated with a combination of anti–CTLA-4 and anti–PD-1…”
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Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma by Magen, Assaf, Hamon, Pauline, Fiaschi, Nathalie, Soong, Brian Y., Park, Matthew D., Mattiuz, Raphaël, Humblin, Etienne, Troncoso, Leanna, D’souza, Darwin, Dawson, Travis, Kim, Joel, Hamel, Steven, Buckup, Mark, Chang, Christie, Tabachnikova, Alexandra, Schwartz, Hara, Malissen, Nausicaa, Lavin, Yonit, Soares-Schanoski, Alessandra, Giotti, Bruno, Hegde, Samarth, Ioannou, Giorgio, Gonzalez-Kozlova, Edgar, Hennequin, Clotilde, Le Berichel, Jessica, Zhao, Zhen, Ward, Stephen C., Fiel, Isabel, Kou, Baijun, Dobosz, Michael, Li, Lianjie, Adler, Christina, Ni, Min, Wei, Yi, Wang, Wei, Atwal, Gurinder S., Kundu, Kunal, Cygan, Kamil J., Tsankov, Alexander M., Rahman, Adeeb, Price, Colles, Fernandez, Nicolas, He, Jiang, Gupta, Namita T., Kim-Schulze, Seunghee, Gnjatic, Sacha, Kenigsberg, Ephraim, Deering, Raquel P., Schwartz, Myron, Marron, Thomas U., Thurston, Gavin, Kamphorst, Alice O., Merad, Miriam

“…Despite no apparent defects in T cell priming and recruitment to tumors, a large subset of T cell rich tumors fail to respond to immune checkpoint blockade…”
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Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program by Park, Sun-Mi, Gönen, Mithat, Vu, Ly, Minuesa, Gerard, Tivnan, Patrick, Barlowe, Trevor S, Taggart, James, Lu, Yuheng, Deering, Raquel P, Hacohen, Nir, Figueroa, Maria E, Paietta, Elisabeth, Fernandez, Hugo F, Tallman, Martin S, Melnick, Ari, Levine, Ross, Leslie, Christina, Lengner, Christopher J, Kharas, Michael G

“…Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Leukemia cells exhibit a dysregulated…”
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Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines by Deering, Raquel P, Kommareddy, Sushma, Ulmer, Jeffrey B, Brito, Luis A, Geall, Andrew J

“…Nucleic acid-based vaccines are being developed as a means to combine the positive attributes of both live-attenuated and subunit vaccines. Viral vectors and…”
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The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins by Li, Ning, Yousefi, Maryam, Nakauka-Ddamba, Angela, Li, Fan, Vandivier, Lee, Parada, Kimberly, Woo, Dong-Hun, Wang, Shan, Naqvi, Ammar S., Rao, Shilpa, Tobias, John, Cedeno, Ryan J., Minuesa, Gerard, Y, Katz, Barlowe, Trevor S., Valvezan, Alexander, Shankar, Sheila, Deering, Raquel P., Klein, Peter S., Jensen, Shane T., Kharas, Michael G., Gregory, Brian D., Yu, Zhengquan, Lengner, Christopher J.

“…Members of the Msi family of RNA-binding proteins have recently emerged as potent oncoproteins in a range of malignancies. MSI2 is highly expressed in…”
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Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs by Park, Sun-Mi, Deering, Raquel P, Lu, Yuheng, Tivnan, Patrick, Lianoglou, Steve, Al-Shahrour, Fatima, Ebert, Benjamin L, Hacohen, Nir, Leslie, Christina, Daley, George Q, Lengner, Christopher J, Kharas, Michael G

“…Hematopoietic stem cells (HSCs) are maintained through the regulation of symmetric and asymmetric cell division. We report that conditional ablation of the…”
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Complete responses to odronextamab in two patients with diffuse large B‐cell lymphoma refractory to chimeric antigen receptor T‐cell therapy by Weinstock, Matt, Elavalakanar, Pavania, Bright, Susan, Ambati, Srikanth R., Brouwer‐Visser, Jurriaan, Pourpe, Stephane, Fiaschi, Nathalie, Jankovic, Vladimir, Thurston, Gavin, Deering, Raquel P., Chaudhry, Aafia, Joyce, Robin, Arnason, Jon

“…Summary Outcomes remain poor for patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (R/R B‐NHL). While chimeric antigen receptor (CAR) T‐cell…”
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Genome-wide analyses and functional profiling of human NK cell lines by Gunesch, Justin T., Angelo, Laura S., Mahapatra, Sanjana, Deering, Raquel P., Kowalko, Johanna E., Sleiman, Patrick, Tobias, John W., Monaco-Shawver, Linda, Orange, Jordan S., Mace, Emily M.

“…•Found 557 genes with >50-fold difference in expression between at least 2 cell lines.•NK92 cells have a CD56bright-like phenotype while YTS cells are…”
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Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses by Amit, Ido, Garber, Manuel, Chevrier, Nicolas, Leite, Ana Paula, Donner, Yoni, Eisenhaure, Thomas, Guttman, Mitchell, Grenier, Jennifer K, Li, Weibo, Zuk, Or, Schubert, Lisa A, Birditt, Brian, Shay, Tal, Goren, Alon, Zhang, Xiaolan, Smith, Zachary, Deering, Raquel, McDonald, Rebecca C, Cabili, Moran, Bernstein, Bradley E, Rinn, John L, Meissner, Alex, Root, David E, Hacohen, Nir, Regev, Aviv

“…Models of mammalian regulatory networks controlling gene expression have been inferred from genomic data but have largely not been validated. We present an…”
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Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells by Vu, Ly P, Prieto, Camila, Amin, Elianna M, Chhangawala, Sagar, Krivtsov, Andrei, Calvo-Vidal, M Nieves, Chou, Timothy, Chow, Arthur, Minuesa, Gerard, Park, Sun Mi, Barlowe, Trevor S, Taggart, James, Tivnan, Patrick, Deering, Raquel P, Chu, Lisa P, Kwon, Jeong-Ah, Meydan, Cem, Perales-Paton, Javier, Arshi, Arora, Gönen, Mithat, Famulare, Christopher, Patel, Minal, Paietta, Elisabeth, Tallman, Martin S, Lu, Yuheng, Glass, Jacob, Garret-Bakelman, Francine E, Melnick, Ari, Levine, Ross, Al-Shahrour, Fatima, Järås, Marcus, Hacohen, Nir, Hwang, Alexia, Garippa, Ralph, Lengner, Christopher J, Armstrong, Scott A, Cerchietti, Leandro, Cowley, Glenn S, Root, David, Doench, John, Leslie, Christina, Ebert, Benjamin L, Kharas, Michael G

“…Michael Kharas and colleagues characterize the MSI2 protein interactome in leukemia cells and subsequently perform a functional screen identifying 24 genes…”
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Rapid TCR:Epitope Ranker (RAPTER): a primary human T cell reactivity screening assay pairing epitope and TCR at single cell resolution by Deering, Raquel P., Blumenberg, Lili, Li, Lianjie, Dhanik, Ankur, Jeong, Se, Pourpe, Stephane, Song, Hang, Boucher, Lauren, Ragunathan, Shoba, Li, Yanxia, Zhong, Maggie, Kuhnert, Jessica, Adler, Christina, Hawkins, Peter, Gupta, Namita T., Moore, Michael, Ni, Min, Hansen, Johanna, Wei, Yi, Thurston, Gavin

“…Identifying epitopes that T cells respond to is critical for understanding T cell-mediated immunity. Traditional multimer and other single cell assays often…”
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Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma by Brouwer-Visser, Jurriaan, Fiaschi, Nathalie, Deering, Raquel P, Cygan, Kamil J, Scott, Darius, Jeong, Se, Boucher, Lauren, Gupta, Namita T, Gupta, Suraj, Adler, Christina, Topp, Max S, Bannerji, Rajat, Duell, Johannes, Advani, Ranjana H, Flink, Dina M, Chaudhry, Aafia, Thurston, Gavin, Ambati, Srikanth R, Jankovic, Vladimir

“…BackgroundPatients with relapsed/refractory B-cell non-Hodgkin lymphoma (R/R B-NHL) have a significant need for effective treatment options. Odronextamab is an…”
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IKBKG (nuclear factor-κB essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function by Salt, Bryn H., MD, Niemela, Julie E., BS, Pandey, Rahul, PhD, Hanson, Eric P., MD, Deering, Raquel P., BA, Quinones, Ralph, MD, Jain, Ashish, MD, Orange, Jordan S., MD, PhD, Gelfand, Erwin W., MD

“…Background Patients with hypomorphic nuclear factor-κB essential modulator ( NEMO ) mutations have extensive phenotypic variability that can include atypical…”
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264 Correlation of virus-specific CD8+ T cells to clinical response following treatment with Pexa-Vec and Cemiplimab in patients with advanced renal cell carcinoma by Dillon, Myles, Li, Lianjie, Bang, Jeongsook, Gaspar, Nicholas, Kuhnert, Jessica, Fiaschi, Nathalie, Jankovic, Vladimir, Lowy, Israel, Thurston, Gavin, Kroog, Glenn, Ha, Kyoung Soo, Deering, Raquel

“…BackgroundTo better understand the immune stimulatory mechanisms of Oncolytic virus (OV), we evaluated the circulating OV-specific T cell response in patients…”
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Development of a Clinical Assay To Evaluate Toll-Like Receptor Function by Deering, Raquel P, Orange, Jordan S

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Common and rare variant associations with clonal haematopoiesis phenotypes by Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric

“…Clonal haematopoiesis involves the expansion of certain blood cell lineages and has been associated with ageing and adverse health outcomes 1 – 5 . Here we use…”
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Abstract CT121: A phase Ib study of recombinant vaccinia virus in combination with immune checkpoint inhibition (ICI) in advanced renal cell carcinoma (RCC) by Rha, Sun Young, Merchan, Jamie, Oh, Sung Yong, Kim, Chan, Bae, Woo Kyun, Lee, Hyun Woo, Dillon, Myles, Deering, Raquel, Kroog, Glenn, Ha, Kyoung Soo

“…Abstract Background: Oncolytic immunotherapy employs viruses that are designed to preferentially replicate in and lyse cancer cells and in this process trigger…”
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Neoadjuvant cemiplimab for resectable hepatocellular carcinoma: a single-arm, open-label, phase 2 trial by Marron, Thomas U, Fiel, Maria Isabel, Hamon, Pauline, Fiaschi, Nathalie, Kim, Edward, Ward, Stephen C, Zhao, Zhen, Kim, Joel, Kennedy, Paul, Gunasekaran, Ganesh, Tabrizian, Parissa, Doroshow, Deborah, Legg, Meredith, Hammad, Ashley, Magen, Assaf, Kamphorst, Alice O, Shareef, Muhammed, Gupta, Namita T, Deering, Raquel, Wang, Wei, Wang, Fang, Thanigaimani, Pradeep, Mani, Jayakumar, Troncoso, Leanna, Tabachnikova, Alexandra, Chang, Christie, Akturk, Guray, Buckup, Mark, Hamel, Steven, Ioannou, Giorgio, Hennequin, Clotilde, Jamal, Hajra, Brown, Haley, Bonaccorso, Antoinette, Labow, Daniel, Sarpel, Umut, Rosenbloom, Talia, Sung, Max W, Kou, Baijun, Li, Siyu, Jankovic, Vladimir, James, Nicola, Hamon, Sara C, Cheung, Hung Kam, Sims, Jennifer S, Miller, Elizabeth, Bhardwaj, Nina, Thurston, Gavin, Lowy, Israel, Gnjatic, Sacha, Taouli, Bachir, Schwartz, Myron E, Merad, Miriam

“…Surgical resection of early stage hepatocellular carcinoma is standard clinical practice; however, most tumours recur despite surgery, and no perioperative…”
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A framework for highly multiplexed dextramer mapping and prediction of T cell receptor sequences to antigen specificity by Zhang, Wen, Hawkins, Peter G, He, Jing, Gupta, Namita T, Liu, Jinrui, Choonoo, Gabrielle, Jeong, Se W, Chen, Calvin R, Dhanik, Ankur, Dillon, Myles, Deering, Raquel, Macdonald, Lynn E, Thurston, Gavin, Atwal, Gurinder S

“…T cell receptor (TCR) antigen-specific recognition is essential for the adaptive immune system. However, building a TCR-antigen interaction map has been…”
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Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes by Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric

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