Search Results - "Deepak, B"
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Toll-like receptor (TLR) agonists as a driving force behind next-generation vaccine adjuvants and cancer therapeutics
Published in Current opinion in chemical biology (01-10-2022)“…Until recently, the development of new human adjuvants was held back by a poor understanding of their mechanisms of action. The field was revolutionized by the…”
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Hydrogeochemical evaluation, suitability, and health risk assessment of groundwater in the watershed of Godavari basin, Maharashtra, Central India
Published in Environmental science and pollution research international (01-04-2021)“…In this investigation, the geochemical progression of a total of 31 groundwater samples of pre-monsoon season was assessed with categorization based on entropy…”
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3
Recent Advances in Gold-Catalyzed N- and O-Functionalizations of Alkynes with Nitrones, Nitroso, Nitro and Nitroxy Species
Published in Advanced synthesis & catalysis (28-04-2016)“…Nitrone and nitroso species are versatile compounds to react with alkenes or butadienes to access five‐ and six‐membered nitroxy (NO) containing heterocycles,…”
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4
Recent advances in genetic tools for engineering probiotic lactic acid bacteria
Published in Bioscience reports (01-01-2023)“…Synthetic biology has grown exponentially in the last few years, with a variety of biological applications. One of the emerging applications of synthetic…”
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5
Weld Seam Detection, Finding, and Setting of Process Parameters for Varying Weld Gap by the Utilization of Laser and Vision Sensor in Robotic Arc Welding
Published in IEEE transactions on industrial electronics (1982) (01-01-2022)“…The prime objective of this article is to obtain maximum weld seam positional accuracy and weld quality with varying weld gap values over weld cycles in laser…”
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Recent advances in steroid amino acid conjugates: Old scaffolds with new dimensions
Published in European journal of medicinal chemistry (01-02-2020)“…Hybrid chemical compounds formed by conjugation of two or more bioactive molecules have shown wide variety of applications in biology, microelectronics as well…”
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An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer
Published in International journal of molecular sciences (12-04-2019)“…The selective expression of CD137 on cells of the immune system (e.g., T and DC cells) and oncogenic cells in several types of cancer leads this molecule to be…”
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Advances in weld seam tracking techniques for robotic welding: A review
Published in Robotics and computer-integrated manufacturing (01-04-2019)“…Use of sensors in robotic welding for controlling the weld quality leads to replacement of manual welding operation in dangerous work environment in presence…”
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9
Diverse chemical space of indoleamine-2,3-dioxygenase 1 (Ido1) inhibitors
Published in European journal of medicinal chemistry (05-02-2021)“…Indoleamine-2,3-dioxygenase 1 (IDO1) catalyses the first and rate limiting step of kynurenine pathway accounting for the major contributor of L-Tryptophan…”
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10
Multi-objective optimization of ethanol fuelled HCCI engine performance using hybrid GRNN–PSO
Published in Applied energy (01-02-2017)“…•Novel GRNN–PSO model for the rapid optimization of the HCCI engine.•At 170°C, a maximum of 45% thermal efficiency is found for ethanol HCCI engine.•Negligible…”
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Complexity-Building Exhaustive Dearomatization of Benzenoid Aromatics within an ESIPT-Initiated Three-Step Photochemical Cascade
Published in Angewandte Chemie International Edition (06-11-2024)“…Dearomative cycloadditions offer rapid access to complex 3D molecular architectures, commonly via a sp2-to-sp3 rehybridization of two atoms of an aromatic…”
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12
Structure activity relationship in β-carboline derived anti-malarial agents
Published in European journal of medicinal chemistry (05-10-2021)“…Malaria, even though an avoidable and treatable disease, can be fatal if ignored. Artemisinin Combination Therapy (ACT) and RTS, S/AS01 vaccine (Mosquirix™)…”
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13
Protocol for eukaryotic plasma membrane isolation using superparamagnetic nanoparticles
Published in Journal of magnetism and magnetic materials (15-04-2019)“…•Phospholipid functionalized Fe3O4 SPMNPs are synthesized for subcellular fractionation.•We report a simplified protocol for SPMNP based Plasma membrane…”
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14
TLR2 Agonistic Small Molecules: Detailed Structure-Activity Relationship, Applications, and Future Prospects
Published in Journal of medicinal chemistry (14-01-2021)“…Toll-like receptors (TLRs) are the pattern recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs) in microbial species…”
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15
Structure-activity relationship in NOD2 agonistic muramyl dipeptides
Published in European journal of medicinal chemistry (05-05-2024)“…Nucleotide-binding oligomerization domain 2 (NOD2) is a receptor of the innate immune system that is capable of perceiving bacterial and viral infections…”
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Applications of geochemical and multivariate statistical approaches for the evaluation of groundwater quality and human health risks in a semi-arid region of eastern Maharashtra, India
Published in Environmental geochemistry and health (01-02-2021)“…A qualitative approach, including geochemical and multivariate statistical approaches, is applied to evaluate the groundwater quality and human health risk,…”
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Call for Papers: Medicinal Chemistry of Next Generation Vaccine Adjuvants
Published in Journal of medicinal chemistry (10-08-2023)Get full text
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18
Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4
Published in Nucleic acids research (24-04-2024)“…Biologically precise enhancer licensing by lineage-determining transcription factors enables activation of transcripts appropriate to biological demand and…”
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An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
Published in Leukemia (01-02-2020)“…Recently, several small molecule drugs were approved for treatment of chronic lymphocytic leukemia (CLL), significantly improving patient management. However,…”
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Gold-Catalyzed Oxidative Cyclizations of cis-3-En-1-ynes To Form Cyclopentenone Derivatives
Published in Angewandte Chemie International Edition (19-03-2012)“…Golden tendencies: The title reaction for synthesizing cyclopentenone derivatives utilizes a gold complex and 8‐methylquinoline oxide as the catalyst system…”
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