Search Results - "Deep, Aakash"

Thiazole-containing compounds as therapeutic targets for cancer therapy by Sharma, Prabodh Chander, Bansal, Kushal Kumar, Sharma, Archana, Sharma, Diksha, Deep, Aakash

“…In the last few decades, considerable progress has been made in anticancer agents development, and several new anticancer agents of natural and synthetic…”
Get full text

Design, synthesis, in silico studies and biological evaluation of 5-((E)-4-((E)-(substituted aryl/alkyl)methyl)benzylidene)thiazolidine-2,4-dione derivatives by Kumar, Harsh, Deep, Aakash, Marwaha, Rakesh Kumar

“…Background Looking at the extensive biological potential of thiazolidine-2,4-dione (TZD) moiety, a new series of thiazolidine-2,4-dione analogues was…”
Get full text

Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents by Deep, Aakash, Bhatia, Richa Kaur, Kaur, Ramanjot, Kumar, Sanjiv, Jain, Upendra Kumar, Singh, Harinder, Batra, Sandeep, Kaushik, Dinesh, Deb, Pran Kishore

“…Imidazo[1,2-a]pyridine is one of the most potential bicyclic 5-6 heterocyclic rings that is recognized as a "drug prejudice" scaffold due to its broad range of…”
Get more information

Herbal products as skincare therapeutic agents against ultraviolet radiation-induced skin disorders by Sharma, Raghu Rai, Deep, Aakash, Abdullah, Sheikh Tasduq

“…This paper aims to highlight the pharmacological aspects of listed herbal skincare products used for the treatment of various disorders caused due to…”
Get full text

Chemical Synthesis, Mechanism of Action and Anticancer Potential of Medicinally Important Thiazolidin-2,4-dione Derivatives: A Review by Kumar, Harsh, Deep, Aakash, Marwaha, Rakesh Kumar

“…Thiazolidin-2,4-dione (TZD) possessing an active methylene constitute an important chemical class of compounds for the development of new drugs. So, many…”
Get more information

An Understanding of Mechanism-Based Approaches for 1,3,4-Oxadiazole Scaffolds as Cytotoxic Agents and Enzyme Inhibitors by Kumar, Davinder, Aggarwal, Navidha, Deep, Aakash, Kumar, Harsh, Chopra, Hitesh, Marwaha, Rakesh Kumar, Cavalu, Simona

“…The world's health system is plagued by cancer and a worldwide effort is underway to find new drugs to treat cancer. There has been a significant improvement…”
Get full text

Thiazolidin-2,4-Dione Scaffold: An Insight into Recent Advances as Antimicrobial, Antioxidant, and Hypoglycemic Agents by Kumar, Harsh, Aggarwal, Navidha, Marwaha, Minakshi Gupta, Deep, Aakash, Chopra, Hitesh, Matin, Mohammed M, Roy, Arpita, Emran, Talha Bin, Mohanta, Yugal Kishore, Ahmed, Ramzan, Mohanta, Tapan Kumar, Saravanan, Muthupandian, Marwaha, Rakesh Kumar, Al-Harrasi, Ahmed

“…Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole family, have generated special interest in terms of their synthetic…”
Get full text

Benzothiazole Derivatives as Potential Anti-Infective Agents by Sharma, Prabodh Chander, Bansal, Kushal Kumar, Deep, Aakash, Pathak, Meenakshi

“…Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents…”
Get more information

Understanding mechanistic aspects and therapeutic potential of natural substances as anticancer agents by Deep, Aakash, Kumar, Davinder, Bansal, Nitin, Narasimhan, Balasubramanian, Marwaha, Rakesh Kumar, Sharma, Prabodh Chander

“…Cancer, a diverse class of illnesses that have a serious impact on the human population, is a severe, complicated challenge in health care delivery and public…”
Get full text

Pharmacological potential of Manilkara zapota (L.) P. Royen (Sapodilla): a narrative review by Priyanka, Sharma, Aakash, Deep, Harish, Kumar, Nitin, Bansal, Sanjiv, Kumar, Arun, Davinder, Kumar

“…Herbal medicine is safe and effective in treating various diseases. Traditional herbal medicine plays a tremendous role in treatment of various diseases and…”
Get full text

Comprehensive review on ethnomedicinal, phytochemistry and pharmacological profile of Ficus Religiosa L by Rahul, Rawat, Harish, Kumar, Neetu, Singh, Aakash, Deep, Balasubramanian, Narasimhan, Surender, Singh Yadav, Sanjiv, Kumar

“…Ficus religiosa L. ( F. religiosa ) or sacred fig is a large perennial tree belonging to the family Moraceae or mulberry family. Though the tree has…”
Get full text

Inhibitor designing, virtual screening, and docking studies for methyltransferase: A potential target against dengue virus by Singh, Jagbir, Kumar, Mahesh, Mansuri, Rani, Sahoo, Ganesh, Deep, Aakash

“…Aim: Aim of this work was to design and identify some S-adenosyl-L-homocysteine (SAH) analogs as inhibitors of S-adenosyl-L-methionine-dependent…”
Get full text

2-Substituted-3-(5-Substituted-1,3,4-oxadiazol/thiadiazol-2-yl) Thiazolidin-4-one Derivatives: Synthesis, Anticancer, Antimicrobial, and Antioxidant Potential by Kumar, Davinder, Aggarwal, Navidha, Kumar, Harsh, Kapoor, Garima, Deep, Aakash, Bibi, Shabana, Sharma, Aastha, Chopra, Hitesh, Kumar Marwaha, Rakesh, Alshammari, Abdulrahman, Alharbi, Metab, Hayee, Abdul

“…In this innovative research, a novel series of thiazolidin-4-one analogues having a 1,3,4-oxadiazole/thiadiazole moiety were derived and the structures of all…”
Get full text

Mechanism-based approaches of 1,3,4 thiadiazole scaffolds as potent enzyme inhibitors for cytotoxicity and antiviral activity by Kumar, Davinder, Kumar, Harsh, Kumar, Virender, Deep, Aakash, Sharma, Aastha, Marwaha, Minakshi Gupta, Marwaha, Rakesh Kumar

“…Significant progress in understanding cancer pathogenesis, it remains one of the leading causes of death after cardiovascular diseases. Similarly viral…”
Get full text

Synthesis, Anticancer, Antimicrobial and Antioxidant Potential of Novel 4-(Substituted phenyl-1,3,4-oxadiazol/thiadiazol-2-yl)-4-(4-substituted phenyl) Azetidin-2-One Derivatives by Kumar, Davinder, Aggarwal, Navidha, Kumar, Virender, Kumar, Harsh, Deep, Aakash, Bibi, Shabana, Chopra, Hitesh, Kumar Marwaha, Rakesh, Alshammari, Abdulrahman, Alharbi, Metab, Hayee, Abdul

“…By exploiting the ample biological potential of 1,3,4-oxadiazole/thiadiazole ring, 4-substitutedphenyl-1,3,4-oxadiazol/Thiadiazol-2-yl)-4-(4-substitutedphenyl)…”
Get full text

Recent advances, challenges and updates on the development of therapeutics for malaria by Nandal, Rimmy, Kumar, Davinder, Aggarwal, Navidha, Kumar, Virender, Narasimhan, Balasubramanian, Marwaha, Rakesh Kumar, Sharma, Prabodh Chander, Kumar, Surender, Bansal, Nitin, Chopra, Hitesh, Deep, Aakash

“…Malaria has developed as a serious worldwide health issue as a result of the introduction of resistant species strains. Because of the common chemo resistance…”
Get full text

HPTLC densitometric quantification of stigmasterol and lupeol from Ficus religiosa by Rathee, Deepti, Rathee, Sushila, Rathee, Permender, Deep, Aakash, Anandjiwala, Sheetal, Rathee, Dharmender

“…This study presents the first report of TLC densitometric method, which has been developed and validated for simultaneous quantification of the two marker…”
Get full text

Synthesis, characterization and pharmacological evaluation of (Z)-2-(5-(biphenyl-4-yl)-3-(1-(imino)ethyl)-2,3-dihydro-1,3,4-oxadiazol-2-yl)phenol derivatives as potent antimicrobial and antioxidant agents by Malhotra, Manav, Rawal, Ravindra K., Malhotra, Dipan, Dhingra, Richa, Deep, Aakash, Sharma, Prabodh Chander

“…The oxadiazole pharmacophore is considered a viable lead structure for the synthesis of more efficacious and broad spectrum antimicrobial agents. The…”
Get full text

Synthesis, Cytotoxic Evaluation, Docking and QSAR Study of N-(4-Oxo- 2-(4-((5-Aryl-1,3,4-Thiadiazol-2-yl)Amino)Phenyl)Thiazolidin-3-yl) Benzamides as Antitubulin Agents by Amit, Chawla, Payal, Chawla, Baghel, U S, Aakash, Deep

“…In the present study an efficient strategy for the synthesis of thiazole and thiadiazole derivatives was developed and clubbed together both of the substituted…”
Get more information

Synthesis, antimicrobial, anticancer evaluation of 2-(aryl)-4- thiazolidinone derivatives and their QSAR studies by Deep, Aakash, Kumar, Pradeep, Narasimhan, Balasubramanian, Ramasamy, Kalavathy, Mani, Vasudevan, Mishra, Rakesh Kumar, Majeed, Abu Bakar Abdul

“…A new class of 4-thiazolidinones clubbed with quinozolinone nucleus has been synthesized. The title compounds were screened for their in vitro antimicrobial…”
Get more information