Search Results - "Deeg, Andreas A."

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease by Wagner, Jens, Ryazanov, Sergey, Leonov, Andrei, Levin, Johannes, Shi, Song, Schmidt, Felix, Prix, Catharina, Pan-Montojo, Francisco, Bertsch, Uwe, Mitteregger-Kretzschmar, Gerda, Geissen, Markus, Eiden, Martin, Leidel, Fabienne, Hirschberger, Thomas, Deeg, Andreas A., Krauth, Julian J., Zinth, Wolfgang, Tavan, Paul, Pilger, Jens, Zweckstetter, Markus, Frank, Tobias, Bähr, Mathias, Weishaupt, Jochen H., Uhr, Manfred, Urlaub, Henning, Teichmann, Ulrike, Samwer, Matthias, Bötzel, Kai, Groschup, Martin, Kretzschmar, Hans, Griesinger, Christian, Giese, Armin

“…In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases, deposits of aggregated disease-specific proteins…”
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Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates by Deeg, Andreas A., Reiner, Anne M., Schmidt, Felix, Schueder, Florian, Ryazanov, Sergey, Ruf, Viktoria C., Giller, Karin, Becker, Stefan, Leonov, Andrei, Griesinger, Christian, Giese, Armin, Zinth, Wolfgang

“…Special diphenyl-pyrazole compounds and in particular anle138b were found to reduce the progression of prion and Parkinson's disease in animal models. The…”
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Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates by Reiner, Anne M., Schmidt, Felix, Ryazanov, Sergey, Leonov, Andrei, Weckbecker, Daniel, Deeg, Andreas A., Griesinger, Christian, Giese, Armin, Zinth, Wolfgang

“…Recently diphenyl-pyrazole (DPP) compounds and especially anle138b were found to reduce the aggregation of α-synuclein or Tau protein in vitro as well as in a…”
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Light-Triggered Aggregation and Disassembly of Amyloid-Like Structures by Deeg, Andreas A., Schrader, Tobias E., Kempter, Susanne, Pfizer, Jose, Moroder, Luis, Zinth, Wolfgang

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Isomerization- and Temperature-Jump-Induced Dynamics of a Photoswitchable β-Hairpin by Deeg, Andreas A., Rampp, Michael S., Popp, Alexander, Pilles, Bert M., Schrader , Tobias E., Moroder, Luis, Hauser, Karin, Zinth, Wolfgang

“…Conformational changes in proteins and peptides can be initiated by diverse processes. This raises the question how the variation of initiation mechanisms is…”
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Isomerization- and Temperature-Jump-Induced Dynamics of a Photoswitchable [beta]-Hairpin by Deeg, Andreas A, Rampp, Michael S, Popp, Alexander, Pilles, Bert M, Schrader, Tobias E, Moroder, Luis, Hauser, Karin, Zinth, Wolfgang

“…Conformational changes in proteins and peptides can be initiated by diverse processes. This raises the question how the variation of initiation mechanisms is…”
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Light‐Triggered Aggregation and Disassembly of Amyloid‐Like Structures by Deeg, Andreas A., Schrader, Tobias E., Kempter, Susanne, Pfizer, Jose, Moroder, Luis, Zinth, Wolfgang

“…Switching amyloids by light: A light‐switchable azobenzene peptide aggregates into amyloid‐like structures when the azobenzene chromophore, incorporated as a…”
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Amyloid-Like Structures Formed by Azobenzene Peptides: Light-Triggered Disassembly by Zinth, Wolfgang, Pfizer, Jose, Strzalka, Halina, Schrader, Tobias E., Deeg, Andreas A., Moroder, Luis

“…The light-driven disassembly process of amyloid-like structures formed by azobenzene model peptides is studied by time-resolved mid-IR spectroscopy from…”
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