Search Results - "Dedov, Vadim N."

Gingerols: a novel class of vanilloid receptor (VR1) agonists by Dedov, Vadim N, Tran, Van H, Duke, Colin C, Connor, Mark, Christie, MacDonald J, Mandadi, Sravan, Roufogalis, Basil D

“…Gingerols, the pungent constituents of ginger, were synthesized and assessed as agonists of the capsaicin‐activated VR1 (vanilloid) receptor. [6]‐Gingerol and…”
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Development of the Internet-Enabled System for Exercise Telerehabilitation and Cardiovascular Training by Dedov, Vadim N, Dedova, Irina V

“…Sustained exercise training could significantly improve patient rehabilitation and management of noncommunicable diseases in the community. This study aimed to…”
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Hypoxia Causes Aggregation of Serine Palmitoyltransferase followed by Non-Apoptotic Death of Human Lymphocytes by Dedov, Vadim N, Dedova, Irina V, Nicholson, Garth A

“…In the central nervous system chronic hypoxia has been suggested to cause neurodegenerations and protein aggregation, as in Alzheimer’s disease. Here we have…”
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Cofilin and DNase I Affect the Conformation of the Small Domain of Actin by Dedova, Irina V., Dedov, Vadim N., Nosworthy, Neil J., Hambly, Brett D., dos Remedios, Cris G.

“…Cofilin binding induces an allosteric conformational change in subdomain 2 of actin, reducing the distance between probes attached to Gln-41 (subdomain 2) and…”
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A bilateral rehabilitation system for the lower limbs by Dedov, Vadim N., Dedova, Irina V.

“…Abstract Purpose: Bilateral and unilateral training equipment for the upper limbs facilitates rehabilitation after stroke. In this work, we tested the first…”
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Activity of partially inhibited serine palmitoyltransferase is sufficient for normal sphingolipid metabolism and viability of HSN1 patient cells by Dedov, Vadim N., Dedova, Irina V., Merrill, Alfred H., Nicholson, Garth A.

“…Hereditary sensory neuropathy type I (HSN1) is a common degenerative disorder of peripheral sensory neurons. HSN1 is caused by mutations in the gene, encoding…”
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Organisation of mitochondria in living sensory neurons by Dedov, Vadim N, Roufogalis, Basil D

“…In this work, we have examined the mitochondrial organisation in living cultured primary dorsal root ganglion (DRG) neurons. Confocal microscopy and the…”
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Equilibrium between cell division and apoptosis in immortal cells as an alternative to the G1 restriction mechanism in mammalian cells by Dedov, Vadim N, Dedova, Irina V, Nicholson, Garth A

“…Starvation arrests cultured mammalian cells in the G(1) restriction point of the cell cycle, whereas cancer cells generally lose the regulatory control of the…”
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Equilibrium Between Cell Division and Apoptosis in Immortal Cells as an Alternative to the G1 Restriction Mechanism in Mammalian Cells by Dedov, Vadim N., Dedova, Irina V., Nicholson, Garth A.

“…Starvation arrests cultured mammalian cells in the G1 restriction point of the cell cycle, whereas cancer cells generally lose the regulatory control of the…”
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Application of a Web-Enabled Leg Training System for the Objective Monitoring and Quantitative Analysis of Exercise-Induced Fatigue by Dedov, Vadim N, Dedova, Irina V

“…Sustained cardiac rehabilitation is the key intervention in the prevention and treatment of many human diseases. However, implementation of exercise programs…”
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Automated Management of Exercise Intervention at the Point of Care: Application of a Web-Based Leg Training System by Dedov, Vadim N, Dedova, Irina V

“…Recent advances in information and communication technology have prompted development of Web-based health tools to promote physical activity, the key component…”
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Rat dorsal root ganglion neurones express different capsaicin-evoked Ca 2+ transients and permeabilities to Mn 2 by Dedov, Vadim N, Roufogalis, Basil D

“…Capsaicin (1 μM) evoked [Ca 2+] i transients in two-thirds of a Percoll-gradient enriched population of rat dorsal root ganglion (DRG) neurones. Amongst the…”
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Rat dorsal root ganglion neurones express different capsaicin-evoked Ca2+ transients and permeabilities to Mn2 by DEDOV, V. N, ROUFOGALIS, B. D

“…Capsaicin (1 microM) evoked [Ca2+]i transients in two-thirds of a Percoll-gradient enriched population of rat dorsal root ganglion (DRG) neurones. Amongst the…”
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Transport of Mitochondria During Axonogenesis by Dedov, Vadim N., Dedova, Irina V., Armati, Patricia J.

“…The cellular mechanisms involved in axonogenesis are still unclear. In the present work we found that formation of neurites in cultured neonatal dorsal root…”
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Three-dimensional organisation of mitochondrial clusters in regenerating dorsal root ganglion (DRG) neurons from neonatal rats: evidence for mobile mitochondrial pools by Dedov, Vadim N., Armati, Patricia J., Roufogalis, Basil D.

“…We report for the first time the rearrangement of mitochondrial arrays in developing dorsal root ganglion (DRG) neurons isolated from neonatal rats in culture…”
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Hypoxia Causes Aggregation of Serine Palmitoyltransferase followed by Non-Apoptotic Death of Human Lymphocytes by Dedov, Vadim N., Dedova, Irina V., Nicholson, Garth A.

“…In the central nervous system chronic hypoxia has been suggested to cause neurodegenerations and protein aggregation, as in Alzheimer's disease. Here we have…”
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