Search Results - "Dederich, Debra"

An improved method for large-scale preparation of negatively and positively supercoiled plasmid DNA by Barth, Marita, Dederich, Debra, Dedon, Peter

“…A rigorous understanding of the biological function of superhelical tension in cellular DNA requires the development of new tools and model systems for study…”
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Glass bead purification of plasmid template DNA for high throughput sequencing of mammalian genomes by Dederich, Debra A., Okwuonu, Geoffrey, Garner, Toni, Denn, Amanda, Sutton, Angelica, Escotto, Michael, Martindale, Ashley, Delgado, Oliver, Muzny, Donna M., Gibbs, Richard A., Metzker, Michael L.

“…To meet the new challenge of generating the draft sequences of mammalian genomes, we describe the development of a novel high throughput 96-well method for the…”
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Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing by Kapranov, Philipp, Chen, Lingxia, Dederich, Debra, Dong, Biao, He, Jie, Steinmann, Kathleen E, Moore, Andrea R, Thompson, John F, Milos, Patrice M, Xiao, Weidong

“…The single-stranded genome of adeno-associated viral (AAV) vectors is one of the key factors leading to slow-rising but long-term transgene expression…”
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