Search Results - "Dede Eren, Aysegul"
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Self-agglomerated collagen patterns govern cell behaviour
Published in Scientific reports (15-01-2021)“…Reciprocity between cells and their surrounding extracellular matrix is one of the main drivers for cellular function and, in turn, matrix maintenance and…”
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2
The loop of phenotype: Dynamic reciprocity links tenocyte morphology to tendon tissue homeostasis
Published in Acta biomaterialia (01-06-2023)“…Cells and their surrounding extracellular matrix (ECM) are engaged in dynamic reciprocity to maintain tissue homeostasis: cells deposit ECM, which in turn…”
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3
Expanding Biomaterial Surface Topographical Design Space through Natural Surface Reproduction
Published in Advanced materials (Weinheim) (01-08-2021)“…Surface topography is a tool to endow biomaterials with bioactive properties. However, the large number of possible designs makes it challenging to find the…”
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4
Identification of topographical architectures supporting the phenotype of rat tenocytes
Published in Acta biomaterialia (01-01-2019)“…[Display omitted] Tenocytes, the main cell type of the tendon, require mechanical stimuli for their proper function. When the tenocyte environment changes due…”
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Solid‐phase silica‐based extraction leads to underestimation of residual DNA in decellularized tissues
Published in Xenotransplantation (Københaven) (01-01-2021)“…Decellularization of animal tissues is a novel route to obtain biomaterials for use in tissue engineering and organ transplantation. Successful…”
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6
Multiscale characterization of pathological bone tissue
Published in Microscopy research and technique (01-02-2022)“…ABSTRACT Bone is a complex natural material with a complex hierarchical multiscale organization, crucial to perform its functions. Ultrastructural analysis of…”
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7
Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose‐derived stem cells
Published in Journal of tissue engineering and regenerative medicine (01-12-2019)“…Identification of a suitable cell source and bioactive agents guiding cell differentiationtowards tenogenic phenotype represents a prerequisite for advancement…”
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8
Cells Dynamically Adapt to Surface Geometry by Remodeling Their Focal Adhesions and Actin Cytoskeleton
Published in Frontiers in cell and developmental biology (03-06-2022)“…Cells probe their environment and adapt their shape accordingly via the organization of focal adhesions and the actin cytoskeleton. In an earlier publication,…”
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High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology
Published in Chemical reviews (28-04-2021)“…The complex interaction of cells with biomaterials (i.e., materiobiology) plays an increasingly pivotal role in the development of novel implants, biomedical…”
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10
Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Published in Biomaterials (01-11-2020)“…We previously found that surface topographies induce the expression of the Scxa gene, encoding Scleraxis in tenocytes. Because Scxa is a TGF-β responsive gene,…”
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11
An off-the-shelf decellularized and sterilized human bone-ACL-bone allograft for anterior cruciate ligament reconstruction
Published in Journal of the mechanical behavior of biomedical materials (01-11-2022)“…Approximately 1% of active individuals participating in sports rupture their anterior cruciate ligaments (ACL) every year, which is currently reconstructed…”
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Decellularized Porcine Achilles Tendon Induces Anti-inflammatory Macrophage Phenotype In Vitro and Tendon Repair In Vivo
Published in Journal of immunology and regenerative medicine (01-06-2020)“…Decellularized tissues and organs from animal sources are widely used in regenerative medicine and tissue engineering. However, in tendon tissue engineering…”
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