Search Results - "Dedda, Umberto Di"
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Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors
Published in PloS one (01-11-2019)“…Gender influences platelet biology. Women have a larger platelet count, but gender-based differences in platelet function remain debated. We performed a study…”
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Impact of Preoperative Anemia on Outcome in Adult Cardiac Surgery: A Propensity-Matched Analysis
Published in The Annals of thoracic surgery (01-10-2012)“…Background Preoperative anemia is not considered an operative mortality risk factor by the majority of the risk stratification tools used in cardiac surgery…”
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The procoagulant pattern of patients with COVID‐19 acute respiratory distress syndrome
Published in Journal of thrombosis and haemostasis (01-07-2020)“…Background Few observations exist with respect to the pro‐coagulant profile of patients with COVID‐19 acute respiratory distress syndrome (ARDS). Reports of…”
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A Comparative Study of SEER Sonorheometry Versus Standard Coagulation Tests, Rotational Thromboelastometry, and Multiple Electrode Aggregometry in Cardiac Surgery
Published in Journal of cardiothoracic and vascular anesthesia (01-06-2019)“…Coagulation point-of-care tests for the diagnosis and management of bleeding commonly are used in cardiac surgery. Recently, a new viscoelastic point-of-care…”
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Platelet Contribution to Clot Strength in Thromboelastometry: Count, Function, or Both?
Published in Platelets (Edinburgh) (02-01-2020)“…In thromboelastometry (ROTEM TM ) the difference in amplitude between the EXTEM and the FIBTEM is considered an index of platelet contribution to clot strength…”
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The Conundrum of Systemic Arterial Pressure Management on Cardiopulmonary Bypass
Published in Journal of clinical medicine (19-01-2023)“…The recently released EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass (CPB) in adult cardiac surgery [...]…”
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Bleeding and Thrombotic Issues during Extracorporeal Membrane Oxygenation
Published in Journal of clinical medicine (13-09-2022)“…Extracorporeal Membrane Oxygenation (ECMO) is an advanced life support modality for patients with respiratory or cardiac failure refractory to standard therapy…”
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Platelet function after cardiac surgery and its association with severe postoperative bleeding: the PLATFORM study
Published in Platelets (Edinburgh) (03-10-2019)“…Platelet dysfunction after cardiac surgery is a determinant of postoperative bleeding. The existing guidelines suggest the use of desmopressin and/or platelet…”
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Covid-19-Associated Coagulopathy: Biomarkers of Thrombin Generation and Fibrinolysis Leading the Outcome
Published in Journal of clinical medicine (28-10-2020)“…Background: Coronavirus Disease 2019 (COVID-19)-associated coagulopathy is characterized by a prothrombotic state not yet comprehensively studied. We…”
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The multifactorial dynamic perfusion index: A predictive tool of cardiac surgery associated acute kidney injury
Published in Perfusion (01-01-2024)“…Introduction cardiac surgery associated acute kidney injury (CSA-AKI) has a number of preoperative and intraoperative risk factors. Cardiopulmonary bypass…”
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Microcirculatory Alterations in Critically Ill Patients with COVID-19-Associated Acute Respiratory Distress Syndrome
Published in Journal of clinical medicine (16-02-2022)“…Presently, a number of specific observations have been performed on microcirculatory function in a coronavirus disease-19 (COVID-19) setting. We hypothesized…”
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Platelet reactivity in overweight and obese patients undergoing cardiac surgery
Published in Platelets (Edinburgh) (04-07-2019)“…Body mass index (BMI) and specifically overweight and obesity have been associated with an increased platelet reactivity in different series of patients. This…”
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Hemodilution on cardiopulmonary bypass as a determinant of early postoperative hyperlactatemia
Published in PloS one (18-05-2015)“…The nadir hematocrit (HCT) on cardiopulmonary bypass (CPB) is a recognized independent risk factor for major morbidity and mortality in cardiac surgery. The…”
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Plasma-Free Strategy for Cardiac Surgery with Cardiopulmonary Bypass in Infants < 10 kg: A Retrospective, Propensity-Matched Study
Published in Journal of clinical medicine (07-06-2023)“…Infants < 10 kg undergoing cardiac surgery with cardiopulmonary bypass (CPB) may receive either fresh frozen plasma (FFP) or other solutions in the CPB priming…”
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When Outcomes Diverge: Age and Cardiovascular Risk as Determinants of Mortality and ICU Admission in COVID-19
Published in Journal of clinical medicine (15-07-2022)“…Background: Hospital mortality and admission to the Intensive Care Unit (ICU) are markers of disease severity in COVID-19 patients. Cardiovascular…”
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In search of the ideal risk-scoring system for very high-risk cardiac surgical patients: a two-stage approach
Published in Journal of cardiothoracic surgery (19-01-2016)“…Cardiac surgery patients at very high risk are difficult to stratify with the existing risk scores. The objective of this study is to assess the clinical…”
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Influence of left ventricular unloading on pediatric post-cardiotomy veno-arterial extracorporeal life support outcomes
Published in Frontiers in cardiovascular medicine (10-08-2022)“…BackgroundThe effectiveness of veno-arterial extracorporeal life support (V-A ECLS) in treating neonatal and pediatric patients with complex congenital heart…”
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Trials and Tribulations of Viscoelastic-Based Determination of Fibrinogen Concentration
Published in Anesthesia and analgesia (01-03-2020)“…Acquired fibrinogen deficiency is a major determinant of severe bleeding in different clinical conditions, including cardiac surgery, trauma, postpartum…”
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Are Viscoelastic Tests Clinically Useful to Identify Platelet-Dependent Bleeding in High-Risk Cardiac Surgery Patients?
Published in Anesthesia and analgesia (01-12-2022)“…Postoperative use of platelet function testing to rule out microvascular bleeding due to platelet dysfunction after cardiac surgery still lacks strong…”
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