Search Results - "Dedaniya, Akshay"

Environmentally sensitive hotspots in the methylome of the early human embryo by Silver, Matt J, Saffari, Ayden, Kessler, Noah J, Chandak, Gririraj R, Fall, Caroline H D, Issarapu, Prachand, Dedaniya, Akshay, Betts, Modupeh, Moore, Sophie E, Routledge, Michael N, Herceg, Zdenko, Cuenin, Cyrille, Derakhshan, Maria, James, Philip T, Monk, David, Prentice, Andrew M

“…In humans, DNA methylation marks inherited from gametes are largely erased following fertilisation, prior to construction of the embryonic methylome…”
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Improved Production and Characterization of Recombinant Human Granulocyte Colony Stimulating Factor from E. coli under Optimized Downstream Processes by Vemula, Sandeep, Thunuguntla, Rahul, Dedaniya, Akshay, Kokkiligadda, Sujana, Palle, Chaitanya, Ronda, Srinivasa Reddy

“…•Isolation of inclusion bodies from frequent sonication and homogenization processes.•Optimized downstream processes enhanced the protein recovery yield.•A…”
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In vitro refolding with simultaneous purification of recombinant human parathyroid hormone (rhPTH 1–34) from Escherichia coli directed by protein folding size exclusion chromatography (PF-SEC): implication of solution additives and their role on aggregates and renaturation by Vemula, Sandeep, Vemula, Sushma, Dedaniya, Akshay, Ronda, Srinivasa Reddy

“…Recombinant proteins are frequently hampered by aggregation during the refolding and purification process. A simple and rapid method for in vitro refolding and…”
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In vitro refolding with simultaneous purification of recombinant human parathyroid hormone : implication of solution additives and their role on aggregates and renaturation by Vemula, Sandeep, Vemula, Sushma, Dedaniya, Akshay, Ronda, Srinivasa Reddy

“…Recombinant proteins are frequently hampered by aggregation during the refolding and purification process. A simple and rapid method for in vitro refolding and…”
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Effect of maternal preconceptional and pregnancy micronutrient interventions on children’s DNA methylation: Findings from the EMPHASIS study by Saffari, Ayden, Shrestha, Smeeta, Issarapu, Prachand, Sajjadi, Sara, Betts, Modupeh, Sahariah, Sirazul Ameen, Tomar, Ashutosh Singh, James, Philip, Dedaniya, Akshay, Yadav, Dilip K, Kumaran, Kalyanaraman, Prentice, Andrew M, Lillycrop, Karen A, Fall, Caroline HD, Chandak, Giriraj R, Silver, Matt J

“…Maternal nutrition in pregnancy has been linked to offspring health in early and later life, with changes to DNA methylation (DNAm) proposed as a mediating…”
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Simplified in vitro refolding and purification of recombinant human granulocyte colony stimulating factor using protein folding cation exchange chromatography by Vemula, Sandeep, Dedaniya, Akshay, Thunuguntla, Rahul, Mallu, Maheswara Reddy, Parupudi, Pavani, Ronda, Srinivasa Reddy

“…•Optimized chromatographic conditions facilitated the efficient mass recovery, purity and specific activity of rhG-CSF.•PF-SCX is an alternative technique for…”
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Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns by Nongmaithem, Suraj S, Beaumont, Robin N, Dedaniya, Akshay, Wood, Andrew R, Ogunkolade, Babatunji-William, Hassan, Zahid, Krishnaveni, Ghattu V, Kumaran, Kalyanaraman, Potdar, Ramesh D, Sahariah, Sirazul A, Krishna, Murali, Di Gravio, Chiara, Mali, Inder D, Sankareswaran, Alagu, Hussain, Akhtar, Bhowmik, Biswajit W, Khan, Abdul Kalam A, Knight, Bridget A, Frayling, Timothy M, Finer, Sarah, Fall, Caroline H D, Yajnik, Chittaranjan S, Freathy, Rachel M, Hitman, Graham A, Chandak, Giriraj R

“…Size at birth is known to be influenced by various fetal and maternal factors, including genetic effects. South Asians have a high burden of low birth weight…”
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FUT Genotypes, Secretor Status, H.pylori Antibody Levels and Vitamin-B12 Concentrations in Indians by Sukla, Krishna, Kunte, Pooja, Kamat, Rajashree, Raut, Deepa, Bhat, Dattatray, Dedaniya, Akshay, Chandak, Giriraj, Chaphekar, Anand, Yajnik, Chittaranjan

“…Background: The FUT2 gene is responsible for the secretion of ABO blood type antigens into the body fluids (saliva, mucous, urine, tears, breast milk, sweat,…”
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Characterization of recombinant human granulocyte colony-stimulating factor expression by FT-IR spectroscopy: Studies on thermal induction and media formulation on the stability of the protein secondary structure by Vemula, Sandeep, Vemula, Sushma, Dedaniya, Akshay, Kante, Rajesh Kumar, Ronda, Srinivasa Reddy

“…The Fourier-transform infrared (FT-IR) spectroscopic approach has been employed to understand the recombinant human G-CSF (rhG-CSF) protein accumulation,…”
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Production of Recombinant Human Granulocyte-Colony Stimulating Factor in Escherichia coli Using Novel Media Supplements Through Integrated Statistical Optimization Designs by Vemula, Sandeep, Dedaniya, Akshay, Bandaru, Rahul, Mallu, Maheswara Reddy, Settaluri, Vijaya Saradhi, Ronda, Srinivasa Reddy

“…This work, for the first time reports the optimization of rhG-CSF in Escherichia coli using novel media supplements. The rhG-CSF production was optimized using…”
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