Search Results - "Decouty, Céline"

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma by Lopez-Rodriguez, Ana Belen, Decouty-Perez, Céline, Farré-Alins, Victor, Palomino-Antolín, Alejandra, Narros-Fernández, Paloma, Egea, Javier

“…Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which…”
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Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux by Farré-Alins, Víctor, Narros-Fernández, Paloma, Palomino-Antolín, Alejandra, Decouty-Pérez, Céline, Lopez-Rodriguez, Ana Belen, Parada, Esther, Muñoz-Montero, Alicia, Gómez-Rangel, Vanessa, López-Muñoz, Francisco, Ramos, Eva, González-Rodríguez, Águeda, Gandía, Luis, Romero, Alejandro, Egea, Javier

“…Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the…”
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Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4 by Palomino-Antolín, Alejandra, Decouty-Pérez, Céline, Farré-Alins, Víctor, Narros-Fernández, Paloma, Lopez-Rodriguez, Ana Belen, Álvarez-Rubal, María, Valencia, Inés, López-Muñoz, Francisco, Ramos, Eva, Cuadrado, Antonio, Casas, Ana I, Romero, Alejandro, Egea, Javier

“…The role of inflammation and immunity in the pathomechanism of neurodegenerative diseases has become increasingly relevant within the past few years. In this…”
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Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients by Farré-Alins, Víctor, Palomino-Antolín, Alejandra, Narros-Fernández, Paloma, Lopez-Rodriguez, Ana Belen, Decouty-Perez, Céline, Muñoz-Montero, Alicia, Zamorano-Fernández, Jorge, Mansilla-Fernández, Beatriz, Giner-García, Javier, García-Feijoo, Pablo, Sáez-Alegre, Miguel, Palpán-Flores, Alexis J., Roda-Frade, José María, Carabias, Cristina S., Rosa, Juliana M., Civantos-Martín, Belén, Yus-Teruel, Santiago, Gandía, Luis, Lagares, Alfonso, Hernández-García, Borja J., Egea, Javier

“…Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide without any validated biomarker or set of biomarkers to help…”
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Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia by Palomino‐Antolin, Alejandra, Narros‐Fernández, Paloma, Farré‐Alins, Víctor, Sevilla‐Montero, Javier, Decouty‐Pérez, Celine, Lopez‐Rodriguez, Ana Belen, Fernández, Nuria, Monge, Luis, Casas, Ana I., Calzada, María José, Egea, Javier

“…Background Inflammasomes are cytosolic multiprotein complexes which, upon assembly, activate the maturation and secretion of the inflammatory cytokines IL‐1β…”
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Synthesis and Pharmacological Evaluation of New N‑Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout by Narros-Fernández, Paloma, Chioua, Mourad, Petcu, Sonia A, Diez-Iriepa, Daniel, Cerrada-Gálvez, Laura, Decouty-Pérez, Céline, Palomino-Antolín, Alejandra, Ramos, Eva, Farré-Alins, Víctor, López-Rodríguez, Ana Belén, Romero, Alejandro, Marco-Contelles, José, Egea, Javier

“…NLRP3 is involved in the pathophysiology of several inflammatory diseases. Therefore, there is high current interest in the clinical development of new NLRP3…”
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TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury by Rosa, Juliana M., Farré‐Alins, Víctor, Ortega, María Cristina, Navarrete, Marta, Lopez‐Rodriguez, Ana Belen, Palomino‐Antolín, Alejandra, Fernández‐López, Elena, Vila‐del Sol, Virginia, Decouty, Céline, Narros‐Fernández, Paloma, Clemente, Diego, Egea, Javier

“…Background and Purpose Activation of astrocytes contributes to synaptic remodelling, tissue repair and neuronal survival following traumatic brain injury…”
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m -Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity by Rocchi, Damiano, González, Juan F, Martín-Cámara, Olmo, Perrone, Maria Grazia, Miciaccia, Morena, Scilimati, Antonio, Decouty-Pérez, Celine, Parada, Esther, Egea, Javier, Menéndez, J Carlos

“…Inhibition of cyclooxygenase-2 (COX-2) has been extensively studied as an approach to reduce proinflammatory markers in acute brain diseases, but the…”
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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome by Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio

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Nox4 is involved in acute kidney injury associated to intravascular hemolysis by García-Caballero, Cristina, Guerrero-Hue, Melania, Vallejo-Mudarra, Mercedes, Palomino Antolin, Alejandra, Decouty-Pérez, Celine, Sánchez-Mendoza, Luz Marina, Villalba, José Manuel, González-Reyes, José Antonio, Opazo-Rios, Lucas, Vázquez-Carballo, Cristina, Herencia, Carmen, Leiva-Cepas, Fernando, Cortegano, Isabel, Andrés, Belén de, Egido, Jesús, Egea, Javier, Moreno, Juan Antonio

“…Massive intravascular hemolysis occurs not unfrequently in many clinical conditions. Breakdown of erythrocytes promotes the accumulation of heme-derivates in…”
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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome by Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty-Pérez, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio

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Im/I-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity by Rocchi, Damiano, González, Juan F, Martín-Cámara, Olmo, Perrone, Maria Grazia, Miciaccia, Morena, Scilimati, Antonio, Decouty-Pérez, Celine, Parada, Esther, Egea, Javier, Menéndez, J. Carlos

“…Inhibition of cyclooxygenase-2 (COX-2) has been extensively studied as an approach to reduce proinflammatory markers in acute brain diseases, but the…”
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