Search Results - "Declèves, X."

Challenges in the Optimisation of Post-operative Pain Management with Opioids in Obese Patients: a Literature Review by Lloret-Linares, C., Lopes, A., Declèves, X., Serrie, A., Mouly, S., Bergmann, J.-F., Perrot, S.

“…An increasing number of obese patients are undergoing surgery, particularly bariatric and orthopaedic surgery. The physiological differences between obese and…”
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Effect of newly synthetized thioxantones on the activity of P-glycoprotein in RBE4 cells: A new approach to minimize the cytotoxicity of xenobiotics by Chaves, C., Silva, R., Palmeira, A., Sousa, E., Pinto, M., Declèves, X., Remião, F.

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Multidrug resistance-associated protein MRP1 expression in human gliomas: chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines overexpressing MRP1 by BENYAHIA, B, HUGUET, S, DECLEVES, X, MOKHTARI, K, CRINIERE, E, BERNAUDIN, J. F, SCHERRMANN, J. M, DELATTRE, J. Y

“…The 190 kDa multidrug resistance protein MRP1 is likely to be involved in the multidrug resistance phenotype of human gliomas. MRP1 expression was evaluated in…”
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Functional expression of p-glycoprotein and multidrug resistance-associated protein (mrp1) in primary cultures of rat astrocytes by Declèves, X., Regina, A., Laplanche, J.-L., Roux, F., Boval, B., Launay, J.-M., Scherrmann, J.-M.

“…Although it has been well established that the drug efflux pump P‐glycoprotein (P‐gp) protects the brain against the entry of cytotoxic drugs, its real in situ…”
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ABC transporters at the blood–brain barrier against neurotoxicity of xenobiotics by Declèves, X.

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Placental Transfer of Maraviroc in an Ex Vivo Human Cotyledon Perfusion Model and Influence of ABC Transporter Expression by VINOT, C, GAVARD, L, GIRAUD, C, TRELUYER, J. M, MANCEAU, S, COURBON, E, SCHERRMANN, J. M, DECLEVES, X, DURO, D, PEYTAVIN, G, MANDELBROT, L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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ABCG2/BCRP transport mechanism revealed through kinetically excited targeted molecular dynamics simulations by Dudas, B., Decleves, X., Cisternino, S., Perahia, D., Miteva, M.A.

“…[Display omitted] ABCG2/BCRP is an ABC transporter that plays an important role in tissue protection by exporting endogenous substrates and xenobiotics. ABCG2…”
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Dextromethorphan Analgesia in a Human Experimental Model of Hyperalgesia by Martin, E, Narjoz, C, Decleves, X, Labat, L, Lambert, C, Loriot, M.-A, Ducheix, G, Dualé, C, Pereira, B, Pickering, G

“…WHAT WE ALREADY KNOW ABOUT THIS TOPICNeuropathic pain, which presents abnormal pain manifestations including allodynia and hyperalgesia, is associated with…”
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ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: Influence of spontaneous syncytialization and induction by glucocorticoids by Manceau, S, Giraud, C, Declèves, X, Scherrmann, J.M, Artiguebieille, F, Goffinet, F, Chappuy, H, Vinot, C, Tréluyer, J.M

“…Abstract Objectives ABC transporters in the human placenta play a major role in protecting the fetus against potential toxic drugs. The glucocorticoid…”
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Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability by Chapy, Hélène, Smirnova, Maria, André, Pascal, Schlatter, Joël, Chiadmi, Fouad, Couraud, Pierre-Olivier, Scherrmann, Jean-Michel, Declèves, Xavier, Cisternino, Salvatore

“…Background: The rate of entry of cocaine into the brain is a critical factor that influences neuronal plasticity and the development of cocaine addiction…”
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Population pharmacokinetic modeling of sustained release lithium in the serum, erythrocytes and urine of patients with bipolar disorder by Couffignal, C., Bertrand, J., Sportiche, S., Jarroir, Marine, El Balkhi, S., Djebrani-Oussedik, N., Poupon, J., Declèves, X., Mentré, F., Bellivier, F.

“…Purpose Lithium (Li), the first-line treatment of bipolar disorder, was first developed as an immediate-release form with a routine therapeutic drug monitoring…”
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Report of severe accidental baclofen intoxication in a healthy 4-year-old boy and review of the literature by de Marcellus, C., le Bot, S., Decleves, X., Baud, F., Renolleau, S., Oualha, M.

“…The number of reports on baclofen intoxication has increased in recent years. Here we report the case of a 4-year-old boy in deep coma who was referred to the…”
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Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes by Manceau, S., Giraud, C., Declèves, X., Batteux, F., Chouzenoux, S., Tang, R., Dauchy, S., Scherrmann, J.M., Weill, B., Morini, J.P., Perrot, J.Y., Tréluyer, J.M.

“…The efficacy of drugs acting within lymphocytes depends on their intracellular concentrations, which could be modulated by membrane efflux transporters…”
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1073P Relationship between basal metabolism, nivolumab clearance and survival in metastatic non-small cell lung cancer patients of the ELY study by Puszkiel, A., Boudou Rouquette, P., Arrondeau, J., Wislez, M., Fabre-Guillevin, E., Bianconi, G., Declèves, X., Jouinot, A., De Percin, S., Alexandre, J., Goldwasser, F., Blanchet, B.

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Development of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strains by Bruyère, A., Declèves, X., Bouzom, F., Proust, L., Martinet, M., Walther, B., Parmentier, Y.

“…The objective of this study was to characterize cytochrome P450 (CYP) activities in both intestinal and hepatic microsomes from Wistar and Sprague-Dawley rats…”
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High Levels of P-Glycoprotein Activity in Human Lymphocytes in the First 6 Months of Life by Giraud, C, Declèves, X, Perrot, JY, Manceau, S, Pannier, E, Firtion, G, Morini, JP, Chappuy, H, Batteux, F, Chouzenoux, S, Scherrmann, JM, Blanche, S, Tréluyer, JM

“…P‐glycoprotein (P‐gp) is an efflux transporter that controls the intracellular concentrations of drugs. Human development may modulate P‐gp function. We…”
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Cannabidiol Increases Proliferation, Migration, Tubulogenesis, and Integrity of Human Brain Endothelial Cells through TRPV2 Activation by Luo, Huilong, Rossi, Elisa, Saubamea, Bruno, Chasseigneaux, Stéphanie, Cochois, Véronique, Choublier, Nina, Smirnova, Maria, Glacial, Fabienne, Perrière, Nicolas, Bourdoulous, Sandrine, Smadja, David M, Menet, Marie-Claude, Couraud, Pierre-Olivier, Cisternino, Salvatore, Declèves, Xavier

“…The effect of cannabidiol (CBD), a high-affinity agonist of the transient receptor potential vanilloid-2 (TRPV2) channel, has been poorly investigated in human…”
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9233 POSTER Pharmacokinetic Intra-individual Variability of Imatinib -Consequences for Therapeutic Drug Monitoring in Chronic Myeloid Leukaemia by Bardin, C, Decleves, X, Vekhoff, A, Labat, L, Chast, F

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P-glycoprotein is more efficient at limiting uptake than inducing efflux of colchicine and vinblastine in HL-60 cells by DECLEVES, X, CHAPPEY, O, BOVAL, B, NIEL, E, SCHERRMANN, J.-M

“…To investigate the role of the P-glycoprotein (P-gp) drug efflux pump in the intracellular disposition of colchicine and vinblastine. Uptake and efflux…”
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TSPO PET as a pharmacodynamic biomarker to image a rat model of diffuse intrinsic pontine human glioma and assess ketogenic diet efficacy by Chevaleyre, C., Caillé, F., Kereselidze, D., Tournier, N., Olaciregui, N.G., Carcaboso, A.M., Declèves, X., Cisternino, S., Auvity, S., Truillet, C.

“…Diffuse intrinsic pontine gliomas (DIPG) are highly infiltrative paediatric gliomas. It remains the first cause of death linked to cerebral tumor in children…”
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