Search Results - "Deckert, J"

45 years German Society of Biological Psychiatry (DGBP) by Riederer, P., Kircher, T., Juckel, G., Domschke, K., Schneider, A., Deckert, J., Falkai, P.

“…The foundation of a German Society of Biological Psychiatry (DGBP) was initiated at the Second World Congress of Biological Psychiatry of the WFSBP in…”
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Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation by Bodenmann, S, Hohoff, C, Freitag, C, Deckert, J, Rétey, J V, Bachmann, V, Landolt, H‐P

“…BACKGROUND AND PURPOSE Prolonged wakefulness impairs sustained vigilant attention, measured with the psychomotor vigilance task (PVT), and induces a…”
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MAOA gene hypomethylation in panic disorder—reversibility of an epigenetic risk pattern by psychotherapy by Ziegler, C, Richter, J, Mahr, M, Gajewska, A, Schiele, M A, Gehrmann, A, Schmidt, B, Lesch, K-P, Lang, T, Helbig-Lang, S, Pauli, P, Kircher, T, Reif, A, Rief, W, Vossbeck-Elsebusch, A N, Arolt, V, Wittchen, H-U, Hamm, A O, Deckert, J, Domschke, K

“…Epigenetic signatures such as methylation of the monoamine oxidase A ( MAOA ) gene have been found to be altered in panic disorder (PD). Hypothesizing temporal…”
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Prevalence and determinants of the precursor stages of heart failure: results from the population-based STAAB cohort study by Morbach, Caroline, Gelbrich, Götz, Tiffe, Theresa, Eichner, Felizitas A, Christa, Martin, Mattern, Renate, Breunig, Margret, Cejka, Vladimir, Wagner, Martin, Heuschmann, Peter U, Störk, Stefan

“…Prevention of heart failure relies on the early identification and control of risk factors. We aimed to identify the frequency and characteristics of…”
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Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review by Gutzeit, Julian, Weiß, M, Nürnberger, C, Lemhöfer, C, Appel, K S, Pracht, E, Reese, J-P, Lehmann, C, Polidori, M C, Hein, G, Deckert, J

“…Post-COVID syndrome (PCS) describes a persistent complex of symptoms following a COVID-19 episode, lasting at least 4 to 12 weeks, depending on the specific…”
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Increased fear learning, spatial learning as well as neophobia in Rgs2−/− mice by Raab, A., Popp, S., Lesch, K.‐P., Lohse, M. J., Fischer, M., Deckert, J., Hommers, L.

“…Anxiety disorders result from a complex interplay of genetic and environmental factors such as stress. On the level of cellular signaling, regulator of G…”
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Individual differences in human fear generalization—pattern identification and implications for anxiety disorders by Stegmann, Y., Schiele, M. A., Schümann, D., Lonsdorf, T. B., Zwanzger, P., Romanos, M., Reif, A., Domschke, K., Deckert, J., Gamer, M., Pauli, P.

“…Previous research indicates that anxiety disorders are characterized by an overgeneralization of conditioned fear as compared with healthy participants…”
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Effects of gender and age on serum concentrations of antidepressants under naturalistic conditions by Unterecker, S., Riederer, P., Proft, F., Maloney, J., Deckert, J., Pfuhlmann, B.

“…Therapeutic drug monitoring (TDM) data of antidepressant drugs are often evaluated using homogeneous samples of selected individuals without psychiatric or…”
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CRP genetic variants are associated with mortality and depressive symptoms in chronic heart failure patients by Kittel-Schneider, S., Kaspar, M., Berliner, D., Weber, H., Deckert, J., Ertl, G., Störk, S., Angermann, C., Reif, A.

“…•CRP genetic risk variants are associated with higher mortality risk in heart failure.•CRP genetic risk variants are associated with higher CRP levels in heart…”
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Attachment style and oxytocin receptor gene variation interact in influencing social anxiety by Notzon, S, Domschke, K, Holitschke, K, Ziegler, C, Arolt, V, Pauli, P, Reif, A, Deckert, J, Zwanzger, P

“…Social anxiety has been suggested to be promoted by an insecure attachment style. Oxytocin is discussed as a mediator of trust and social bonding as well as a…”
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Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing by Weber, H, Richter, J, Straube, B, Lueken, U, Domschke, K, Schartner, C, Klauke, B, Baumann, C, Pané-Farré, C, Jacob, C P, Scholz, C-J, Zwanzger, P, Lang, T, Fehm, L, Jansen, A, Konrad, C, Fydrich, T, Wittmann, A, Pfleiderer, B, Ströhle, A, Gerlach, A L, Alpers, G W, Arolt, V, Pauli, P, Wittchen, H-U, Kent, L, Hamm, A, Kircher, T, Deckert, J, Reif, A

“…Corticotropin-releasing hormone (CRH) is a major regulator of the hypothalamic–pituitary–adrenal axis. Binding to its receptor CRHR1 triggers the downstream…”
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Influence of two functional polymorphisms in NOS1 on baseline cortisol and working memory in healthy subjects by Roth, N.J., Zipperich, S., Kopf, J., Deckert, J., Reif, A.

“…The neuronal isoform of the nitric oxide synthase (NOS-I) encoded by NOS1 is the main source of nitric oxide (NO) in the brain. Reduced NO signaling in the…”
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BNST and amygdala activation to threat: Effects of temporal predictability and threat mode by Siminski, N., Böhme, S., Zeller, J.B.M., Becker, M.P.I., Bruchmann, M., Hofmann, D., Breuer, F., Mühlberger, A., Schiele, M.A., Weber, H., Schartner, C., Deckert, J., Pauli, P., Reif, A., Domschke, K., Straube, T., Herrmann, M.J.

“…•BNST is more involved during initial threat anticipation compared to the CM.•CM is more involved during threat confrontation compared to the BNST.•Temporal…”
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MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy by Reif, A, Richter, J, Straube, B, Höfler, M, Lueken, U, Gloster, A T, Weber, H, Domschke, K, Fehm, L, Ströhle, A, Jansen, A, Gerlach, A, Pyka, M, Reinhardt, I, Konrad, C, Wittmann, A, Pfleiderer, B, Alpers, G W, Pauli, P, Lang, T, Arolt, V, Wittchen, H-U, Hamm, A, Kircher, T, Deckert, J

“…Panic disorder with agoraphobia (PD/AG) is a prevalent mental disorder featuring a substantial complex genetic component. At present, only a few established…”
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GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder by Deckert, J, Weber, H, Villmann, C, Lonsdorf, T B, Richter, J, Andreatta, M, Arias-Vasquez, A, Hommers, L, Kent, L, Schartner, C, Cichon, S, Wolf, C, Schaefer, N, von Collenberg, C R, Wachter, B, Blum, R, Schümann, D, Scharfenort, R, Schumacher, J, Forstner, A J, Baumann, C, Schiele, M A, Notzon, S, Zwanzger, P, Janzing, J G E, Galesloot, T, Kiemeney, L A, Gajewska, A, Glotzbach-Schoon, E, Mühlberger, A, Alpers, G, Fydrich, T, Fehm, L, Gerlach, A L, Kircher, T, Lang, T, Ströhle, A, Arolt, V, Wittchen, H-U, Kalisch, R, Büchel, C, Hamm, A, Nöthen, M M, Romanos, M, Domschke, K, Pauli, P, Reif, A

“…The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still largely unknown and progress is hampered by small sample sizes. We…”
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Neuropeptide S receptor gene - converging evidence for a role in panic disorder by Domschke, K, Reif, A, Weber, H, Richter, J, Hohoff, C, Ohrmann, P, Pedersen, A, Bauer, J, Suslow, T, Kugel, H, Heindel, W, Baumann, C, Klauke, B, Jacob, C, Maier, W, Fritze, J, Bandelow, B, Krakowitzky, P, Rothermundt, M, Erhardt, A, Binder, E B, Holsboer, F, Gerlach, A L, Kircher, T, Lang, T, Alpers, G W, Ströhle, A, Fehm, L, Gloster, A T, Wittchen, H-U, Arolt, V, Pauli, P, Hamm, A, Deckert, J

“…Animal studies have suggested neuropeptide S (NPS) and its receptor (NPSR) to be involved in the pathogenesis of anxiety-related behavior. In this study, a…”
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The interaction of early life experiences with COMT val158met affects anxiety sensitivity by Baumann, C., Klauke, B., Weber, H., Domschke, K., Zwanzger, P., Pauli, P., Deckert, J., Reif, A.

“…The pathogenesis of anxiety disorders is considered to be multifactorial with a complex interaction of genetic factors and individual environmental factors…”
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Cognitive remediation for bipolar patients with objective cognitive impairment: a naturalistic study by Veeh, J., Kopf, J., Kittel-Schneider, S., Deckert, J., Reif, A.

“…Background Many bipolar patients (BP) are affected by cognitive impairments and reduced psychosocial function even after complete remission. In the present…”
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A neuropeptide S receptor variant associated with overinterpretation of fear reactions: a potential neurogenetic basis for catastrophizing by Raczka, K A, Gartmann, N, Mechias, M-L, Reif, A, Büchel, C, Deckert, J, Kalisch, R

“…Neuropeptide S (NPS) is a recently discovered G protein-coupled receptor ligand that modulates fear-like behaviors in rodents. A frequent A>T single-nucleotide…”
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The CD37-targeted antibody–drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model by Beckwith, K A, Frissora, F W, Stefanovski, M R, Towns, W H, Cheney, C, Mo, X, Deckert, J, Croce, C M, Flynn, J M, Andritsos, L A, Jones, J A, Maddocks, K J, Lozanski, G, Byrd, J C, Muthusamy, N

“…Therapeutic regimens for chronic lymphocytic leukemia (CLL) have increasingly utilized monoclonal antibodies since the chimeric anti-CD20 antibody rituximab…”
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