Search Results - "Dec, Alexander M."

Facilitation of corticostriatal transmission following pharmacological inhibition of striatal phosphodiesterase 10A: role of nitric oxide-soluble guanylyl cyclase-cGMP signaling pathways by Padovan-Neto, Fernando E, Sammut, Stephen, Chakroborty, Shreaya, Dec, Alexander M, Threlfell, Sarah, Campbell, Peter W, Mudrakola, Vishnu, Harms, John F, Schmidt, Christopher J, West, Anthony R

“…The striatum contains a rich variety of cyclic nucleotide phosphodiesterases (PDEs), which play a critical role in the regulation of cAMP and cGMP signaling…”
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Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington’s Disease by Chakroborty, Shreaya, Manfredsson, Fredric P., Dec, Alexander M., Campbell, Peter W., Stutzmann, Grace E., Beaumont, Vahri, West, Anthony R.

“…Huntington’s disease (HD) results from abnormal expansion in CAG trinucleotide repeats within the HD gene, a mutation which leads to degeneration of striatal…”
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Impact of neonatal NOS-1 inhibitor exposure on neurobehavioural measures and prefrontal-temporolimbic integration in the rat nucleus accumbens by Dec, Alexander M., Kohlhaas, Kathy L., Nelson, Christopher L., Hoque, Kristina E., Leilabadi, Solmaz N., Folk, Jessica, Wolf, Marina E., West, Anthony R.

“…Nitric oxide (NO) is a gaseous neurotransmitter that plays a significant role in the establishment and refinement of functional neural circuits. Genetic and…”
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