Search Results - "Debruyne, J C"

PET visualization of microglia in multiple sclerosis patients using [11C]PK11195 by Debruyne, J. C., Versijpt, J., Van Laere, K. J., De Vos, F., Keppens, J., Strijckmans, K., Achten, E., Slegers, G., Dierckx, R. A., Korf, J., De Reuck, J. L.

“…Activated microglia are involved in the immune response of multiple sclerosis (MS). The peripheral benzodiazepine receptor (PBR) is expressed on microglia and…”
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Microglial imaging with positron emission tomography and atrophy measurements with magnetic resonance imaging in multiple sclerosis: a correlative study by Versijpt, J, Debruyne, J C, Van Laere, K J, De Vos, F, Keppens, J, Strijckmans, K, Achten, E, Slegers, G, Dierckx, R A, Korf, J, De Reuck, J L

“…Objective: The objectives of the present study were to assess brain atrophy in multiple sclerosis (MS) patients during different disease stages and to…”
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Semiquantification of the peripheral-type benzodiazepine ligand [11C]PK11195 in normal human brain and application in multiple sclerosis patients by Debruyne, Jan C, Van Laere, Koen J, Versijpt, Jan, De Vos, Filip, Eng, Johan Keppens, Strijckmans, Karel, Santens, Patrick, Achten, Eric, Slegers, Guido, Korf, Jacob, Dierckx, Rudi A, De Reuck, Jacques L

“…[11C]PK11195 is a peripheral-benzodiazepine-receptor radioligand used for detection of microglial inflammation. Normal uptake by means of semiquantification…”
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