Search Results - "Debruyne, C."

Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression by Van San, Emily, Debruyne, Angela C., Veeckmans, Geraldine, Tyurina, Yulia Y., Tyurin, Vladimir A., Zheng, Hao, Choi, Sze Men, Augustyns, Koen, van Loo, Geert, Michalke, Bernhard, Venkataramani, Vivek, Toyokuni, Shinya, Bayir, Hülya, Vandenabeele, Peter, Hassannia, Behrouz, Vanden Berghe, Tom

“…Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous (CNS) demyelination resulting in axonal injury and neurological…”
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Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non–Small-Cell Lung Cancer by van Meerbeeck, Jan P., Kramer, Gijs W. P. M., Van Schil, Paul E. Y., Legrand, Catherine, Smit, Egbert F., Schramel, Franz, Tjan-Heijnen, Vivianne C., Biesma, Bonne, Debruyne, Channa, van Zandwijk, Nico, Splinter, Ted A. W., Giaccone, Giuseppe

“…Background Induction chemotherapy before surgical resection increases survival compared with surgical resection alone in patients with stage IIIA-N2…”
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Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975 by Efficace, F, Bottomley, A, Smit, EF, Lianes, P, Legrand, C, Debruyne, C, Schramel, F, Smit, HJ, Gaafar, R, Biesma, B, Manegold, C, Coens, C, Giaccone, G, Van Meerbeeck, J

“…Background: The aim of this prognostic factor analysis was to investigate if a patient's self-reported health-related quality of life (HRQOL) provided…”
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PET visualization of microglia in multiple sclerosis patients using [11C]PK11195 by Debruyne, J. C., Versijpt, J., Van Laere, K. J., De Vos, F., Keppens, J., Strijckmans, K., Achten, E., Slegers, G., Dierckx, R. A., Korf, J., De Reuck, J. L.

“…Activated microglia are involved in the immune response of multiple sclerosis (MS). The peripheral benzodiazepine receptor (PBR) is expressed on microglia and…”
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Gemcitabine and Cisplatin as Induction Regimen for Patients With Biopsy-Proven Stage IIIA N2 Non–Small-Cell Lung Cancer: A Phase II Study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group (EORTC 08955) by VAN ZANDWIJK, M, SMIT, E. F, GIACCONE, G, KRAMER, G. W. P, SCHRAMEL, F, GANS, S, FESTEN, J, TERMEER, A, SCHLOSSER, N. J. J, DEBRUYNE, C, CURRAN, D

“…Our objective was to better define the activity/feasibility of gemcitabine/cisplatin (GC) as induction chemotherapy in patients with stage IIIA N2…”
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Microglial imaging with positron emission tomography and atrophy measurements with magnetic resonance imaging in multiple sclerosis: a correlative study by Versijpt, J, Debruyne, J C, Van Laere, K J, De Vos, F, Keppens, J, Strijckmans, K, Achten, E, Slegers, G, Dierckx, R A, Korf, J, De Reuck, J L

“…Objective: The objectives of the present study were to assess brain atrophy in multiple sclerosis (MS) patients during different disease stages and to…”
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Balance between the cell viability and death in 3D by Debruyne, Angela C., Okkelman, Irina A., Dmitriev, Ruslan I.

“…Cell death is a phenomenon, frequently perceived as an absolute event for cell, tissue and the organ. However, the rising popularity and complexity of such 3D…”
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Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases: a phase II study of the EORTC Lung Cancer Group (08965) by Dziadziuszko, R, Ardizzoni, A, Postmus, P.E, Smit, E.F, Price, A, Debruyne, C, Legrand, C, Giaccone, G

“…This study was performed to evaluate the activity of single-agent temozolomide in two groups of chemotherapy-naı̈ve non-small cell lung cancer (NSCLC)…”
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Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients by Debruyne, Angela C., Okkelman, Irina A., Heymans, Nina, Pinheiro, Cláudio, Hendrix, An, Nobis, Max, Borisov, Sergey M., Dmitriev, Ruslan I.

“…Assessment of hypoxia, nutrients, metabolite gradients, and other hallmarks of the tumor microenvironment within 3D multicellular spheroid and organoid models…”
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Tunable Self-Referenced Molecular Thermometers via Manipulation of Dual Emission in Platinum(II) Pyridinedipyrrolide Complexes by Russegger, Andreas, Fischer, Susanne M., Debruyne, Angela C., Wiltsche, Helmar, Boese, A. Daniel, Dmitriev, Ruslan I., Borisov, Sergey M.

“…Optical temperature sensors based on self-referenced readout schemes such as the emission ratio and the decay time are crucial for a wide range of…”
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Bright and Photostable TADF‐Emitting Zirconium(IV) Pyridinedipyrrolide Complexes: Efficient Dyes for Decay Time‐Based Temperature Sensing and Imaging by Russegger, Andreas, Debruyne, Angela C., Berrio, Daniel Carvajal, Fuchs, Stefanie, Marzi, Julia, Schenke‐Layland, Katja, Dmitriev, Ruslan I., Borisov, Sergey M.

“…Luminescence thermometry represents a technique of choice for measurements in small objects and imaging of temperature distribution. However, most…”
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72PD LOBECTOMY IN COMBINATION WITH RADICAL LYMPHADENECTOMY IS THE MOST FREQUENT SURGICAL INTERVENTION PERFORMED IN PATIENTS RANDOMIZED IN MAGRIT TRIAL EVALUATING MAGE-A3 ANTIGEN-SPECIFIC CANCER IMMUNOTHERAPEUTIC (ASCI) AS ADJUVANT TREATMENT IN STAGE IB IIIA NSCLC by Zielinski, M, Zo, J, Vanakesa, T, Dahabreh, J, Hoffmann, H, Holzer, M, Mitsudomi, T, Tada, H, Asamura, H, Debruyne, C

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Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: An EORTC double-blind placebo-controlled phase III study by Tjan-Heijnen, V. C. G., Postmus, P. E., Ardizzoni, A., Manegold, Ch, Burghouts, J., van Meerbeeck, J., Gans, S., Mollers, M., Buchholz, E., Biesma, B., Legrand, C., Debruyne, C., Giaccone, G.

“…Summary Background: CDE (cyclophosphamide, doxorubicin, etoposide) is one of the standard chemotherapy regimens in the treatment of small-cell lung cancer…”
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European Organization for Research and Treatment of Cancer (EORTC) 08957 Phase II Study of Topotecan in Combination with Cisplatin as Second-Line Treatment of Refractory and Sensitive Small Cell Lung Cancer by ARDIZZONI, Andrea, MANEGOLD, Christian, NEUMAIER, Carlo, KING, Kathrine, GIACCONE, Giuseppe, DEBRUYNE, Channa, GAAFAR, Rabab, BUCHHOLZ, Erika, SMIT, Egbert F, LIANES, Pilar, TEN VELDE, Guul, BOSQUEE, Lionel, LEGRAND, Catherine

“…Purpose: The purpose of this study was to assess the activity and toxicity of a combined regimen of topotecan and cisplatin in “sensitive” (s) and “refractory”…”
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Production and Multi-Parameter Live Cell Fluorescence Lifetime Imaging Microscopy (FLIM) of Multicellular Spheroids by Debruyne, Angela C, Ferrari, Gabriele, Zhou, Hang, Van Loon, Nore, Heymans, Nina, Okkelman, Irina A, Dmitriev, Ruslan I

“…Multicellular tumor spheroids are a popular 3D tissue microaggregate model for reproducing tumor microenvironment, testing and optimizing drug therapies and…”
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The activity of raltitrexed (Tomudex®) in malignant pleural mesothelioma: an EORTC phase II study (08992) by Baas, P., Ardizzoni, A., Grossi, F., Nackaerts, K., Numico, G., Van Marck, E., van de Vijver, M., Monetti, F., Smid-Geirnaerdt, M.J.A., van Zandwijk, N., Debruyne, C., Legrand, C., Giaccone, G.

“…We investigated the activity and toxicity of raltitrexed (Tomudex®) as a single agent treatment in patients with Malignant Pleural Mesothelioma (MPM) in a…”
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Carboplatin and paclitaxol (Taxol) as an induction regimen for patients with biopsy-proven stage IIIA N2 non-small cell lung cancer: an EORTC phase II study (EORTC 08958) by O'Brien, M.E.R, Splinter, T, Smit, E.F, Biesma, B, Krzakowski, M, Tjan-Heijnen, V.C.G, Van Bochove, A, Stigt, J, Smid-Geirnaerdt, M.J.A, Debruyne, C, Legrand, C, Giaccone, G

“…The aim of this study was to document the activity and toxicity of paclitaxel (Taxol)/carboplatin when used as induction chemotherapy in patients with stage…”
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Power injection by distributed generation and the influence of harmonic load conditions by Desmet, J, Debruyne, C, Vanalme, J, Vandevelde, L

“…The number of installed distributed generation (DG) in residential areas rapidly increases, specifically in the form of photovoltaics (PV), causing some…”
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MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (ASCI) as adjuvant therapy in resected stage IB/II non-small cell lung cancer (NSCLC): from proof-of-concept to phase III trial (MAGRIT) by Eisen, T, Vansteenkiste, J, Zielinski, M, Linder, A, Dahabreh, J, Jassem, J, Passlick, B, Debruyne, C

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102PD MAGE-A3 ANTIGEN-SPECIFIC CANCER IMMUNOTHERAPEUTIC (ASCI) AS ADJUVANT THERAPY IN RESECTED STAGE IB/II NON-SMALL CELL LUNG CANCER (NSCLC): FROM PROOF-OF-CONCEPT TO PHASE III TRIAL (MAGRIT) by Passlick, B, Vansteenkiste, J, Zielinski, M, Linder, A, Dahabreh, J, Esteban, E, Malinowski, W, Jassem, J, Lopez-Brea, M, Debruyne, C

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