Search Results - "Debre, Patrice"

Molecularly Imprinted Polymer Nanoparticles as Potential Synthetic Antibodies for Immunoprotection against HIV by Xu, Jingjing, Merlier, Franck, Avalle, Bérangère, Vieillard, Vincent, Debré, Patrice, Haupt, Karsten, Tse Sum Bui, Bernadette

“…We describe the preparation and characterization of synthetic antibodies based on molecularly imprinted polymer nanoparticles (MIP-NPs) for the recognition and…”
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Cell-Mediated Immune Responses to COVID-19 Infection by Guihot, Amélie, Litvinova, Elena, Autran, Brigitte, Debré, Patrice, Vieillard, Vincent

“…An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan…”
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Challenges and Issues of Anti-SARS-CoV-2 Vaccines by Blumental, Sophie, Debré, Patrice

“…At the beginning of 2021, anti-SARS-CoV-2 vaccination campaigns had been launched in almost 60 countries with more than 500 million doses having been…”
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NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs by Béziat, Vivien, Descours, Benjamin, Parizot, Christophe, Debré, Patrice, Vieillard, Vincent

“…Terminal differentiation of NK cells is crucial in maintaining broad responsiveness to pathogens and discriminating normal cells from cells in distress…”
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Evidence of premature immune aging in patients thymectomized during early childhood by Sauce, Delphine, Larsen, Martin, Fastenackels, Solène, Duperrier, Anne, Keller, Michael, Grubeck-Loebenstein, Beatrix, Ferrand, Christophe, Debré, Patrice, Sidi, Daniel, Appay, Victor

“…While the thymus is known to be essential for the initial production of T cells during early life, its contribution to immune development remains a matter of…”
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NK Cytotoxicity against CD4+T Cells during HIV-1 Infection: A gp41 Peptide Induces the Expression of an NKp44 Ligand by Vieillard, Vincent, Strominger, Jack L., Debré, Patrice, Dausset, Jean

“…HIV infection leads to a state of chronic immune activation and progressive deterioration in immune function, manifested most recognizably by the progressive…”
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Epidemics: lessons from History by Debré, Patrice

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HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway by Fausther-Bovendo, Hugues, Vieillard, Vincent, Sagan, Sandrine, Bismuth, Georges, Debré, Patrice

“…CD4(+) T cell loss is central to HIV pathogenesis. In the initial weeks post-infection, the great majority of dying cells are uninfected CD4(+) T cells. We…”
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The francophone network on neglected tropical diseases by Jannin, Jean, Solano, Philippe, Quick, Isadora, Debre, Patrice

“…[...]it also envisions bridging with other existing European and African NTD networks. First activities Mapping exercise The first achievement of the network…”
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Specific Phenotypic and Functional Features of Natural Killer Cells From HIV-Infected Long-Term Nonprogressors and HIV Controllers by VIEILLARD, Vincent, FAUSTHER-BOVENDO, Hugues, SAMRI, Assia, DEBRE, Patrice

“…Recent evidence suggests that natural killer (NK) cells play a crucial role in the HIV pathogenesis. Long-term nonprogressor (LTNP) and HIV controllers are…”
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Life Course Education, Health, and Ageing Well: A Short Inter-Academic Report by Frangos, Emilia, Barriguete-Mélendez, Armando, Debré, Patrice, Gutiérrez Robledo, Luis Miguel, Parodi, André-Laurent, Michel, Jean-Pierre

“…After the first wave of the COVID-19 pandemic, during which the severity of the disease in certain countries was attributed to a lack of basic education of the…”
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Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients by Achour, Abla, Baychelier, Florence, Besson, Caroline, Arnoux, Armelle, Marty, Michel, Hannoun, Laurent, Samuel, Didier, Debré, Patrice, Vieillard, Vincent

“…Solid cancers are a major adverse outcome of orthotopic liver transplantation (OLT). Although the use of chronic immunosuppression is known to play a role in T…”
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B7-H6-mediated downregulation of NKp30 in natural killer cells contributes to HIV-2 immune escape by Lucar, Olivier, Sadjo Diallo, Mariama, Bayard, Charles, Samri, Assia, Tarantino, Nadine, Debré, Patrice, Thiébaut, Rodolphe, Brun-Vézinet, Françoise, Matheron, Sophie, Cheynier, Rémi, Vieillard, Vincent

“…OBJECTIVE:HIV-1 and HIV-2 differ notably in their epidemiology, with worldwide HIV-1 spread and HIV-2 mainly confined to West Africa. Natural killer (NK) cells…”
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HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2+ NK cells in Lassa virus infection by Wauquier, Nadia, Petitdemange, Caroline, Tarantino, Nadine, Maucourant, Christopher, Coomber, Moinya, Lungay, Victor, Bangura, James, Debré, Patrice, Vieillard, Vincent

“…Lassa virus (LASV) is the etiologic agent of an acute hemorrhagic fever endemic in West Africa. Natural killer (NK) cells control viral infections in part…”
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Accumulation of Intrahepatic TNF-a-Producing NKp44 NK Cells Correlates With Liver Fibrosis and Viral Load in Chronic HCV Infection by Nel, Isabelle, Lucar, Olivier, Petitdemange, Caroline, Béziat, Vivien, Lapalus, Martine, Bédossa, Pierre, Debré, Patrice, Asselah, Tarik, Marcellin, Patrick, Vieillard, Vincent

“…In the setting of chronic hepatitis C virus (HCV) infection, changes in natural killer (NK) cells have been shown to reflect activation in response to virus…”
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Idiopathic CD4 Lymphocytopenia: Clinical and Immunologic Characteristics and Follow-Up of 40 Patients by Régent, Alexis, Autran, Brigitte, Carcelain, Guislaine, Cheynier, Rémi, Terrier, Benjamin, Charmeteau-De Muylder, Bénédicte, Krivitzky, Alain, Oksenhendler, Eric, Costedoat-Chalumeau, Nathalie, Hubert, Pascale, Lortholary, Olivier, Dupin, Nicolas, Debré, Patrice, Guillevin, Loïc, Mouthon, Luc

“…Idiopathic CD4 T lymphocytopenia (ICL) is a rare and severe condition with limited available data. We conducted a French multicenter study to analyze the…”
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Natural Killer Lymphocytes Are Dysfunctional in Kidney Transplant Recipients on Diagnosis of Cancer by Peraldi, Marie-Noëlle, Berrou, Jeannig, Venot, Marion, Chardiny, Victor, Durrbach, Antoine, Vieillard, Vincent, Debré, Patrice, Charron, Dominique, Suberbielle, Caroline, Chevret, Sylvie, Glotz, Denis, Dulphy, Nicolas, Toubert, Antoine

“…BACKGROUNDThe incidence of cancer is increased after solid organ transplantation. Natural killer (NK) cells are key effectors of the tumor immune response…”
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HIV escape from natural killer cytotoxicity: nef inhibits NKp44L expression on CD4+ T cells by FAUSTHER-BOVENDO, Hugues, SOL-FOULON, Nathalie, CANDOTTI, Daniel, AGUT, Henri, SCHWARTZ, Olivier, DEBRE, Patrice, VIEILLARD, Vincent

“…HIV infection induces a progressive depletion of CD4 T cells. We showed that NKp44L, a cellular ligand for an activating natural killer (NK) receptor, is…”
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vaccine strategy against AIDS: An HIV gp41 peptide immunization prevents NKp44L expression and CD4⁺ T cell depletion in SHIV-infected macaques by Vieillard, Vincent, Le Grand, Roger, Dausset, Jean, Debré, Patrice

“…We previously showed that a gp41 peptide (3S) induces expression of a natural killer (NK) ligand (NKp44L) on CD4⁺ T cells during HIV-1 infection and that those…”
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NKp44L: A new tool for fighting cancer by Vieillard, Vincent, Baychelier, Florence, Debré, Patrice

“…We have recently identified that the ligand of natural cytotoxicity triggering receptor 2 (NCR2, best known as NKp44) is expressed on a large panel of…”
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