Search Results - "Debono, J"

American Society of Clinical Oncology Statement: Toward Individualized Care for Patients With Advanced Cancer by PEPPERCORN, Jeffrey M, SMITH, Thomas J, HELFT, Paul R, DEBONO, David J, BERRY, Scott R, WOLLINS, Dana S, HAYES, Daniel M, VON ROENN, Jamie H, SCHNIPPER, Lowell E

“…Patients with advanced incurable cancer face complex physical, psychological, social, and spiritual consequences of disease and its treatment. Care for these…”
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Antitumour activity of docetaxel following treatment with the CYP17A1 inhibitor abiraterone: clinical evidence for cross-resistance? by Mezynski, J., Pezaro, C., Bianchini, D., Zivi, A., Sandhu, S., Thompson, E., Hunt, J., Sheridan, E., Baikady, B., Sarvadikar, A., Maier, G., Reid, A.H.M., Mulick Cassidy, A., Olmos, D., Attard, G., de Bono, J.

“…Abiraterone and docetaxel are both approved treatments for men with metastatic castration-resistant prostate cancer (mCRPC). Abiraterone pre-docetaxel is…”
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1119 The management of breast cancer patients from first contact to surgery in Malta: Are there any delays in the system? by Magri, D, Mifsud, R, Debono, J

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Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’ by Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.

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Caring for patients with chronic pain: pearls and pitfalls by Debono, David J, Hoeksema, Laura J, Hobbs, Raymond D

“…Chronic, nonmalignant pain is a substantial public health problem in the United States. Research over the past 2 decades has defined chronic pain by using a…”
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Cross-Layer Design for Optimized Region of Interest of Ultrasound Video Data Over Mobile WiMAX by Debono, C. J., Micallef, B. W., Philip, N. Y., Alinejad, A., Istepanian, R. S. H., Amso, N. N.

“…The application of advanced error concealment techniques applied as a postprocess to conceal lost video information in error-prone channels, such as the…”
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Experimentally Determined Diagnostic Ions for Identification of Peptide Glycotopes by DeBono, Nicholas J., Moh, Edward S. X., Packer, Nicolle H.

“…The analysis of the structures of glycans present on glycoproteins is an essential component for determining glycoprotein function; however, detailed glycan…”
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LDPCA Code Construction for Slepian-Wolf Coding by Micallef, J. J., Farrugia, R. A., Debono, C. J.

“…Error correcting codes used for Distributed Source Coding (DSC) generally assume a random distribution of errors. However, in certain DSC applications,…”
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SSSMuG: Same Sample Sequential Multi-Glycomics by Moh, Edward S. X., Dalal, Sagar, DeBono, Nicholas J., Kautto, Liisa, Wongtrakul-Kish, Katherine, Packer, Nicolle H.

“…The mammalian glycome is structurally complex and diverse, composed of many glycan classes such as N- and O-linked glycans, glycosaminoglycans (GAGs),…”
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Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives by Muthiah, Divya, Henshaw, Georgia K, DeBono, Aaron J, Capuano, Ben, Scammells, Peter J, Callaghan, Richard

“…The antitussive agent noscapine has been shown to inhibit the proliferation of cancer cells by disruption of tubulin dynamic. However, the efficacy of several…”
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Decision analysis for avoiding postchemotherapy surgery in patients with disseminated nonseminomatous germ cell tumors by Debono, D J, Heilman, D K, Einhorn, L H, Donohue, J P

“…This retrospective study was undertaken to assess the outcome of patients with disseminated nonseminomatous germ cell tumor (NSGCT) managed under a…”
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Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network by Lee, Richard G., Rudler, Danielle L., Raven, Samuel A., Peng, Liuyu, Chopin, Anaëlle, Moh, Edward S. X., McCubbin, Tim, Siira, Stefan J., Fagan, Samuel V., DeBono, Nicholas J., Stentenbach, Maike, Browne, Jasmin, Rackham, Filip F., Li, Ji, Simpson, Kaylene J., Marcellin, Esteban, Packer, Nicolle H., Reid, Gavin E., Padman, Benjamin S., Rackham, Oliver, Filipovska, Aleksandra

“…The structures and functions of organelles in cells depend on each other but have not been systematically explored. We established stable knockout cell lines…”
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Substituted Pyridazin-3(2H)‑ones as Highly Potent and Biased Formyl Peptide Receptor Agonists by Deora, Girdhar Singh, Qin, Cheng Xue, Vecchio, Elizabeth A, Debono, Aaron J, Priebbenow, Daniel L, Brady, Ryan M, Beveridge, Julia, Teguh, Silvia C, Deo, Minh, May, Lauren T, Krippner, Guy, Ritchie, Rebecca H, Baell, Jonathan B

“…Herein we describe the development of a focused series of functionalized pyridazin-3­(2H)-one-based formyl peptide receptor (FPR) agonists that demonstrate…”
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8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase by Dennis, Matthew L., Lee, Michael D., Harjani, Jitendra R., Ahmed, Mohamed, DeBono, Aaron J., Pitcher, Noel P., Wang, Zhong‐Chang, Chhabra, Sandeep, Barlow, Nicholas, Rahmani, Raphaël, Cleary, Ben, Dolezal, Olan, Hattarki, Meghan, Aurelio, Luigi, Shonberg, Jeremy, Graham, Bim, Peat, Thomas S., Baell, Jonathan B., Swarbrick, James D.

“…Dihydropteroate synthase (DHPS) is an enzyme of the folate biosynthesis pathway, which catalyzes the formation of 7,8‐dihydropteroate (DHPt) from…”
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A Cross-Layer CQI Feedback Reduction Technique for MVD Transmission in Crowd Event Scenarios by Cordina, Mario, Debono, Carl J.

“…It is attractive to deploy free-viewpoint video (FVV) systems based on the multi-view video plus depth (MVD) representation in crowd event scenarios, as it…”
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Synthesis and Biological Evaluation of N-Substituted Noscapine Analogues by DeBono, Aaron J., Xie, Jin Han, Ventura, Sabatino, Pouton, Colin W., Capuano, Ben, Scammells, Peter J.

“…Noscapine is a phthalideisoquinoline alkaloid isolated from the opium poppy Papaver somniferum. It has long been used as an antitussive agent, but has more…”
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Quantifying sclerotic bone metastases with 2D ultra short TE MRI: a feasibility study by Messiou, C, Collins, D J, Morgan, V A, Robson, M D, deBono, J S, Bydder, G M, deSouza, N M

“…Ultra Short TE MRI allows signal to be detected from tissues with a very short T2.The aims of this study were to optimize a 2D UTE MRI sequence for imaging and…”
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Structural Basis for the Selective Binding of Inhibitors to 6‑Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli by Dennis, Matthew L, Pitcher, Noel P, Lee, Michael D, DeBono, Aaron J, Wang, Zhong-Chang, Harjani, Jitendra R, Rahmani, Raphaël, Cleary, Ben, Peat, Thomas S, Baell, Jonathan B, Swarbrick, James D

“…6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) is a member of the folate biosynthesis pathway found in prokaryotes and lower eukaryotes that…”
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The Synthesis and Biological Evaluation of Multifunctionalised Derivatives of Noscapine as Cytotoxic Agents by DeBono, Aaron J., Mistry, Sarah J., Xie, Jinhan, Muthiah, Divya, Phillips, Jackson, Ventura, Sabatino, Callaghan, Richard, Pouton, Colin W., Capuano, Ben, Scammells, Peter J.

“…Noscapine, a phthalideisoquinoline alkaloid derived from Papaver somniferum, is a well‐known antitussive drug that has a relatively safe in vitro toxicity…”
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190 (PB178): BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress by Varkaris, A., Wang, K., Kozlova, N., Nouri, M., Stavridi, A., Einstein, D., DeBono, J., Corey, E., Sharp, A., Balk, S.

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