Search Results - "Debold, C R"

Psychiatric phenomenology in Cushing's disease by Loosen, P T, Chambliss, B, DeBold, C R, Shelton, R, Orth, D N

“…We evaluated 20 patients with Cushing's disease (i.e., Cushing's syndrome due to ACTH-secreting pituitary microadenoma) and 20 patients with Major Depressive…”
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Plasma corticotropin and cortisol responses to ovine corticotropin-releasing hormone (CRH), arginine vasopressin (AVP), CRH plus AVP, and CRH plus metyrapone in patients with Cushing's disease by DICKSTEIN, G, DEBOLD, C. R, GAITAN, D, DECHERNEY, G. S, JACKSON, R. V, SHELDON, W. R, NICHOLSON, W. E, ORTH, D. N

“…The CRH test may sometimes be useful in the differential diagnosis of Cushing's syndrome, because most patients with pituitary ACTH-dependent Cushing's…”
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Effect of synthetic ovine corticotropin-releasing factor. Dose response of plasma adrenocorticotropin and cortisol by Orth, D N, Jackson, R V, DeCherney, G S, DeBold, C R, Alexander, A N, Island, D P, Rivier, J, Rivier, C, Spiess, J, Vale, W

“…Synthetic ovine corticotropin-releasing factor (CRF) was administered to normal male volunteer subjects as an intravenous bolus or 30-s infusion. Doses of CRF…”
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Immunoreactive proopiomelanocortin (POMC) peptides and POMC-like messenger ribonucleic acid are present in many rat nonpituitary tissues by DeBold, C R, Nicholson, W E, Orth, D N

“…Immunoreactive (IR) POMC peptides have been found in several rat nonpituitary tissues. We found IR-ACTH, IR-beta-endorphin (beta END), and IR-gamma MSH in…”
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Lymphocyte-derived adrenocorticotropin is insufficient to stimulate adrenal steroidogenesis in hypophysectomized rats by Olsen, N J, Nicholson, W E, DeBold, C R, Orth, D N

“…Cells of the immune system can produce and respond to peptide hormones associated with the endocrine system. However, the physiological significance of these…”
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Case report: coronary vasospasm--relation to the hyperthyroid state by Moliterno, D, DeBold, C R, Robertson, R M

“…While angina is not uncommonly seen in association with hyperthyroidism, only rare case reports have suggested that myocardial ischemia in this state may be…”
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Arginine vasopressin potentiates adrenocorticotropin release induced by ovine corticotropin-releasing factor by DEBOLD, C. R, SHELDON, W. R, DECHERNEY, G. S, JACKSON, R. V, ALEXANDER, A. N, VALE, W, RIVIER, J, ORTH, D. N

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Effect of altered thyroid hormone levels on hypothalamic-pituitary-adrenal function by Kamilaris, T C, DeBold, C R, Pavlou, S N, Island, D P, Hoursanidis, A, Orth, D N

“…To determine whether alterations in serum thyroid hormone levels affect hypothalamic-pituitary-adrenal function, we measured the plasma immunoreactive (IR)…”
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Diurnal variation in the response of plasma adrenocorticotropin and cortisol to intravenous ovine corticotropin-releasing hormone by DeCherney, G S, DeBold, C R, Jackson, R V, Sheldon, Jr, W R, Island, D P, Orth, D N

“…To determine whether the plasma immunoreactive ACTH (IR-ACTH) and IR-cortisol responses to ovine corticotropin-releasing hormone (oCRH) depend on the time of…”
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Single subcutaneous doses of a luteinizing hormone-releasing hormone antagonist suppress serum gonadotropin and testosterone levels in normal men by Pavlou, S N, Debold, C R, Island, D P, Wakefield, G, Rivier, J, Vale, W, Rabin, D

“…The ability of single doses of a LHRH antagonist [Ac-delta 3Pro1, 4F-D-Phe2, D-Trp3,6]LHRH (4F-antagonist) to suppress serum gonadotropin and testosterone…”
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Proopiomelanocortin gene expression in a pheochromocytoma using upstream transcription initiation sites by DeBold, C R, Mufson, E E, Menefee, J K, Orth, D N

“…The proopiomelanocortin (POMC) gene is expressed in many normal nonpituitary tissues, in addition to the pituitary. POMC-derived peptides have also been…”
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Effect of synthetic ovine corticotropin-releasing factor: prolonged duration of action and biphasic response of plasma adrenocorticotropin and cortisol by DeBold, C R, DeCherney, G S, Jackson, R V, Sheldon, W R, Alexander, A N, Island, D P, Rivier, J, Vale, W, Orth, D N

“…The duration of the response to synthetic ovine corticotropin-releasing factor (CRF) was studied in 13 healthy male volunteer subjects. Placebo or CRF (0.3, 3,…”
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Plasma distribution, disappearance half-time, metabolic clearance rate, and degradation of synthetic ovine corticotropin-releasing factor in man by Nicholson, W E, DeCherney, G S, Jackson, R V, DeBold, C R, Uderman, H, Alexander, A N, Rivier, J, Vale, W, Orth, D N

“…The plasma distribution, disappearance half-time, MCR, and degradation of corticotropin-releasing factor (CRF) were studied in normal men who received a pulse…”
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Effect of ovine corticotropin-releasing hormone administered during insulin-induced hypoglycemia on plasma adrenocorticotropin and cortisol by DeCherney, G S, DeBold, C R, Jackson, R V, Sheldon, Jr, W R, Kamilaris, T C, Island, D P, Orth, D N

“…The factors that mediate the hypothalamic-pituitary response to hypoglycemia in man are unknown. To investigate the role of CRH in the plasma ACTH response to…”
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Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer by Gaitan, D, DeBold, C R, Turney, M K, Zhou, P, Orth, D N, Kovacs, W J

“…ACTH secretion by tumors of nonpituitary origin is characteristically resistant to negative feedback regulation by glucocorticoids. One possible mechanism for…”
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Adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia: an unusual cause of Cushing's syndrome by Malchoff, C D, Rosa, J, DeBold, C R, Kozol, R A, Ramsby, G R, Page, D L, Malchoff, D M, Orth, D N

“…Inappropriate ACTH secretion with bilateral diffuse or macronodular adrenal hyperplasia is the most common cause of Cushing's syndrome. This report describes a…”
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Use of hypothalamic releasing factors to examine the effects of increased testosterone on pituitary response in a postmenopausal woman. A case report by Hill, G A, Herbert, C M, DeBold, C R, Wentz, A C

“…Hyperandrogenic states in women may alter hypothalamic pituitary response. The pituitary function of a 64-year-old postmenopausal woman with a…”
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Algorithm‐Based Qualitative and Semiquantitative Identification of Prevalent Vertebral Fracture: Agreement Between Different Readers, Imaging Modalities, and Diagnostic Approaches by Ferrar, Lynne, Jiang, Guirong, Schousboe, John T, DeBold, Charles R, Eastell, Richard

“…We compared SQ and ABQ diagnosis of VF imaged by radiography and X‐ray absorptiometry. Mild ABQ VF had stronger associations with osteoporosis than mild SQ VF…”
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Proopiomelanocortin gene is expressed in many normal human tissues and in tumors not associated with ectopic adrenocorticotropin syndrome by DeBold, C R, Menefee, J K, Nicholson, W E, Orth, D N

“…Immunoreactive (IR) POMC peptides have been detected in several human nonpituitary tissues and most pheochromocytomas and lung cancers, including those not…”
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Effects of short and long duration hypothyroidism and hyperthyroidism on the plasma adrenocorticotropin and corticosterone responses to ovine corticotropin-releasing hormone in rats by Kamilaris, T C, DeBold, C R, Johnson, E O, Mamalaki, E, Listwak, S J, Calogero, A E, Kalogeras, K T, Gold, P W, Orth, D N

“…We report here a study of the plasma ACTH and corticosterone responses to synthetic ovine CRH (oCRH) in hypothyroid and hyperthyroid rats studied 7, 15, and 60…”
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