Search Results - "Debnath, Sabyasachi"
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Abstract 5322: Discovery of CRD1601, a potent and selective HPK1 inhibitor with robust in vivo anti-cancer activity
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Background: Haematopoietic Progenitor Kinase (HPK-1, MAP4K1) is a member of the STE20 family of serine/threonine kinases, expressed predominantly in…”
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Journal Article -
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Abstract 3510: Small molecule ACSS2 inhibitors target acetate metabolizing tumor cells in hypoxic conditions
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…BACKGROUND Tumors such as glioblastoma proliferating under hypoxic, hypoglycemic and hypolipidemic conditions derive almost half of their nutritional…”
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Abstract 2122: CRD1600 is a potent HPK-I inhibitor with robust immune modulatory properties
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Background: Haematopoietic Progenitor Kinase (HPK-1, MAP4K1) is a member of the STE20 family of serine/threonine kinases, expressed predominantly in…”
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Journal Article