Search Results - "Debatisse, Justine"
-
1
Clinical Imaging of the Penumbra in Ischemic Stroke: From the Concept to the Era of Mechanical Thrombectomy
Published in Frontiers in cardiovascular medicine (09-03-2022)“…The ischemic penumbra is defined as the severely hypoperfused, functionally impaired, at-risk but not yet infarcted tissue that will be progressively recruited…”
Get full text
Journal Article -
2
Relationships between cerebral tau and glucose metabolism in cognitively normal older adults
Published in Alzheimer's & dementia (01-06-2023)“…Background Alzheimer’s disease (AD) is characterised by the accumulation of amyloid‐β and tau in the brain and subsequent neurodegeneration. The relationship…”
Get full text
Journal Article -
3
Is cortical grey matter diffusivity an early biomarker for neuronal damage?
Published in Alzheimer's & dementia (01-12-2022)“…Background There is growing evidence that pathological changes in Alzheimer’s disease (AD) begin several years before the symptom onset. Neuroimaging…”
Get full text
Journal Article -
4
Colocalization of cortical diffusivity changes and microglial activation in dementia
Published in Alzheimer's & dementia (01-12-2022)“…Background There is growing evidence that microglial activation plays a crucial role in the early pathological changes reported in Alzheimer’s disease (AD)…”
Get full text
Journal Article -
5
Longitudinal evolution of neuropathological substrates of Alzheimer’s disease in obese patients
Published in Alzheimer's & dementia (01-12-2022)“…Background Obesity is a metabolic condition with increasing prevalence all over the world. Patients with a body mass index (BMI) higher than 30 are considered…”
Get full text
Journal Article -
6
Cortical diffusivity associates with early neuronal damage
Published in Alzheimer's & dementia (01-12-2022)“…Background Diffusion weighted imaging can provide a marker a microstructural damage which cannot be detected by conventional structural MRI. Changes in…”
Get full text
Journal Article -
7
SB-258585 reduces food motivation while blocking 5-HT 6 receptors in the non-human primate striatum
Published in Progress in neuro-psychopharmacology & biological psychiatry (13-02-2024)“…The interest in new 5-HT₆ agents stems from their ability to modulate cognition processing, food motivation and anxiety-like behaviors. While these findings…”
Get full text
Journal Article -
8
SB-258585 reduces food motivation while blocking 5-HT6 receptors in the non-human primate striatum
Published in Progress in neuro-psychopharmacology & biological psychiatry (20-04-2024)“…The interest in new 5-HT₆ agents stems from their ability to modulate cognition processing, food motivation and anxiety-like behaviors. While these findings…”
Get full text
Journal Article -
9
Spatio-Temporal Characterization of Brain Inflammation in a Non-human Primate Stroke Model Mimicking Endovascular Thrombectomy
Published in Neurotherapeutics (01-04-2023)“…Reperfusion therapies in acute ischemic stroke have demonstrated their efficacy in promoting clinical recovery. However, ischemia/reperfusion injury and…”
Get full text
Journal Article -
10
A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs
Published in Journal of cerebral blood flow and metabolism (01-04-2021)“…Stroke is a devastating disease. Endovascular mechanical thrombectomy is dramatically changing the management of acute ischemic stroke, raising new challenges…”
Get full text
Journal Article -
11
The PREMISE database of 20 Macaca fascicularis PET/MRI brain images available for research
Published in Lab animal (01-01-2024)“…Non-human primate studies are unique in translational research, especially in neurosciences where neuroimaging approaches are the preferred methods used for…”
Get full text
Journal Article -
12
PET-MRI nanoparticles imaging of blood–brain barrier damage and modulation after stroke reperfusion
Published in Brain communications (01-01-2020)“…Abstract In an acute ischaemic stroke, understanding the dynamics of blood–brain barrier injury is of particular importance for the prevention of symptomatic…”
Get full text
Journal Article -
13
Cortical inflammation and brain signs of high-risk atherosclerosis in a non-human primate model
Published in Brain communications (01-01-2021)“…Abstract Atherosclerosis is a chronic systemic inflammatory disease, inducing cardiovascular and cerebrovascular acute events. A role of neuroinflammation is…”
Get full text
Journal Article