Search Results - "Debarun Das"

Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips by Prantil-Baun, Rachelle, Novak, Richard, Das, Debarun, Somayaji, Mahadevabharath R, Przekwas, Andrzej, Ingber, Donald E

“…Physiologically based pharmacokinetic (PBPK) modeling and simulation approaches are beginning to be integrated into drug development and approval processes…”
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Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips by Herland, Anna, Maoz, Ben M., Das, Debarun, Somayaji, Mahadevabharath R., Prantil-Baun, Rachelle, Novak, Richard, Cronce, Michael, Huffstater, Tessa, Jeanty, Sauveur S. F., Ingram, Miles, Chalkiadaki, Angeliki, Benson Chou, David, Marquez, Susan, Delahanty, Aaron, Jalili-Firoozinezhad, Sasan, Milton, Yuka, Sontheimer-Phelps, Alexandra, Swenor, Ben, Levy, Oren, Parker, Kevin K., Przekwas, Andrzej, Ingber, Donald E.

“…Analyses of drug pharmacokinetics (PKs) and pharmacodynamics (PDs) performed in animals are often not predictive of drug PKs and PDs in humans, and in vitro PK…”
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Advances in Porous Biomaterials for Dental and Orthopaedic Applications by Mour, Meenakshi, Das, Debarun, Winkler, Thomas, Hoenig, Elisa, Mielke, Gabriela, Morlock, Michael M., Schilling, Arndt F.

“…The connective hard tissues bone and teeth are highly porous on a micrometer scale, but show high values of compression strength at a relatively low weight…”
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Motion analysis of sun salutation using magnetometer and accelerometer by Omkar, Sn, Mour, Meenakshi, Das, Debarun

“…Sun salutation is a part of yoga. It consists of a sequence of postures done with synchronized breathing. The practice of few cycles of sun salutation is known…”
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A New Level A Type IVIVC for the Rational Design of Clinical Trials Toward Regulatory Approval of Generic Polymeric Long-Acting Injectables by Somayaji, Mahadevabharath R., Das, Debarun, Przekwas, Andrzej

“…Chronic neuropsychiatric disorders and diabetes mellitus affect millions of patients and require long-term supervision and expensive medical care. Although…”
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Computational approaches for modeling and analysis of human-on-chip systems for drug testing and characterization by Somayaji, Mahadevabharath R., Das, Debarun, Przekwas, Andrzej

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An integrated biophysical model for predicting the clinical pharmacokinetics of transdermally delivered compounds by Somayaji, Mahadevabharath R., Das, Debarun, Garimella, Harsha Teja, German, Carrie L., Przekwas, Andrzej J., Simon, Laurent

“…•A holistic skin model linked to a systems pharmacology model is presented.•The skin model predicts the permeation of tool compounds.•The effects of chemical…”
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Drug testing and characterization using human-on-chip (HoC) systems: some thoughts on the application of in vitro–in vivo correlation by Somayaji, Mahadevabharath R., Das, Debarun, Przekwas, Andrzej J.

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Efficient Monitoring of Dynamic Spectrum Access for Robust and Reliable Detection of Unauthorized Access by Das, Debarun, Znati, Taieb, Weiss, Martin B.H.

“…Success of dynamic spectrum access depends on automated enforcement of spectrum access policies. To this end, we undertake a crowdsourced approach to spectrum…”
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Enhanced capture of magnetic microbeads using combination of reduced magnetic field strength and sequentially switched electroosmotic flow--a numerical study by Das, Debarun, Al-Rjoub, Marwan F, Banerjee, Rupak K

“…Magnetophoretic immunoassay is a widely used technique in lab-on-chip systems for detection and isolation of target cells, pathogens, and biomolecules. In this…”
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Quantitative prediction of human drug pharmacokinetic responses using multiple vascularized organ chips coupled by fluid transfer by Herland, Anna, Maoz, Ben M., Das, Debarun, Somayaji, Mahadevabharath R., Prantil-Baun, Rachelle, Novak, Richard, Cronce, Michael, Huffstater, Tessa, Jeanty, Sauveur S. F., Ingram, Miles, Chalkiadaki, Angeliki, Chou, David Benson, Clauson, Susan, Delahanty, Aaron, Jalili-Firoozinezhad, Sasan, Milton, Yuka, Sontheimer-Phelps, Alexandra, Swenor, Ben, Levy, Oren, Parker, Kevin K., Przekwas, Andrzej, Ingber, Donald E.

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A mathematical model of effects on specific joints during practice of the Sun Salutation – A sequence of yoga postures by Omkar, S.N, Mour, Meenakshi, Das, Debarun

“…Summary The ‘Sun Salutation’ consists of a sequence of ten yoga postures, each posture counteracting the preceding one producing a balance between flexion and…”
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A robotic platform for fluidically-linked human body-on-chips experimentation by Novak, Richard, Ingram, Miles, Clauson, Susan, Das, Debarun, Delahanty, Aaron, Herland, Anna, Maoz, Ben M., Jeanty, Sauveur S. F., Somayaji, Mahadevabharath R., Burt, Morgan, Calamari, Elizabeth, Chalkiadaki, Angeliki, Cho, Alexander, Choe, Youngjae, Chou, David Benson, Cronce, Michael, Dauth, Stephanie, Divic, Toni, Fernandez-Alcon, Jose, Ferrante, Thomas, Ferrier, John, FitzGerald, Edward A., Fleming, Rachel, Jalili-Firoozinezhad, Sasan, Grevesse, Thomas, Goss, Josue A., Hamkins-Indik, Tiama, Henry, Olivier, Hinojosa, Chris, Huffstater, Tessa, Jang, Kyung-Jin, Kujala, Ville, Leng, Lian, Mannix, Robert, Milton, Yuka, Nawroth, Janna, Nestor, Bret A., Ng, Carlos F., O'Connor, Blakely, Park, Tae-Eun, Sanchez, Henry, Sliz, Josiah, Sontheimer-Phelps, Alexandra, Swenor, Ben, Thompson, Guy, Touloumes, George J., Tranchemontagne, Zachary, Wen, Norman, Yadid, Moran, Bahinski, Anthony, Hamilton, Geraldine A., Levner, Daniel, Levy, Oren, Przekwas, Andrzej, Prantil-Baun, Rachelle, Parker, Kevin K., Ingber, Donald E.

“…Here we describe of an ‘Interrogator’ instrument that uses liquid-handling robotics, a custom software package, and an integrated mobile microscope to enable…”
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Bioresorption and degradation of biomaterials by Das, Debarun, Zhang, Ziyang, Winkler, Thomas, Mour, Meenakshi, Gunter, Christina, Morlock, Michael, Machens, Hans-Gunther, Schilling, Arndt F

“…The human body is a composite structure, completely constructed of biodegradable materials. This allows the cells of the body to remove and replace old or…”
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Spectrum Misuse Detection in Cooperative Wireless Networks by Das, Debarun, Rose, J.Stepanie, Znati, Taieb, Bustamante, Pedro, Weiss, Martin, Gomez, Marcela M.

“…Cooperative wireless networks, enabled by Cognitive Radios, facilitate mobile users to dynamically share access to spectrum. However, spectrum bands can be…”
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Matchmaking of Volunteers and Channels for Dynamic Spectrum Access Enforcement by Das, Debarun, Znati, Taieb, Weiss, Martin B.H., Gomez, Marcela M., Bustamante, Pedro, Rose, J. Stephanie

“…The success of dynamic spectrum sharing in wireless networks depends on reliable automated enforcement of spectrum access policies. In this paper, a…”
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