Search Results - "Debaene, F."
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Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies
Published in Journal of mass spectrometry. (01-02-2015)“…Antibodies represent a family of clinically relevant compounds with growing commercial potential. From a market perspective, their large size and structural…”
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Supramolecular Luminescent Lanthanide Dimers for Fluoride Sequestering and Sensing
Published in Angewandte Chemie (07-07-2014)“…Lanthanide complexes (Ln=Eu, Tb, and Yb) that are based on a C2‐symmetric cyclen scaffold were prepared and characterized. The addition of fluoride anions to…”
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Functional and Structural Characterization of 2‑Amino-4-phenylthiazole Inhibitors of the HIV‑1 Nucleocapsid Protein with Antiviral Activity
Published in ACS chemical biology (19-09-2014)“…The nucleocapsid protein (NC) is a highly conserved protein in diverse HIV-1 subtypes that plays a central role in virus replication, mainly by interacting…”
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Self-assembly of PNA-encoded peptides into microarrays
Published in Methods in molecular biology (Clifton, N.J.) (2009)“…Several technologies have been described to immobilize libraries of small molecules or peptides in a microarray format. Herein, we describe protocols for an…”
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A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions
Published in Retrovirology (12-11-2012)“…Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that block HIV…”
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Use of virtual screening for discovering anti-retroviral compounds interacting with the HIV-1 nucleocapsid protein
Published in Virus research (2012)Get full text
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7
Synthesis of a PNA-encoded cysteine protease inhibitor library
Published in Tetrahedron (20-09-2004)“…Peptide nucleic acids (PNAs) have been used to encode a combinatorial library whereby each compound is labeled with a PNA tag which reflects its synthetic…”
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Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis
Published in Organic letters (13-11-2003)“…A practical and efficient method for PNA synthesis using an azide group to mask the N-terminus is reported. The deprotection was carried out in 5 min, while…”
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Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays
Published in Chemistry & biology (01-10-2004)“…Enzymatic activity in the fecal droppings from the house dust mite has been postulated to contribute to the elicited allergic response. Screening dust mite…”
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